Two more UCLH patients to receive pioneering treatment for CJD 

13/12/2018 00:00 
Two more patients of University College London Hospitals NHS Foundation Trust (UCLH) are to be given a pioneering treatment for Creutzfeldt-Jakob disease (CJD).
 

In October 2018, we began treating a patient with sporadic CJD with a drug which had not been used in humans before after a judge confirmed that it was lawful and in the patient’s best interests to receive the unlicensed treatment.

UCLH will now be giving the antibody treatment to a second and third patient.

Professor John Collinge, director of the MRC Prion Unit at UCL, who led the development of the antibody, said: “It is still very early days for this treatment but we are very pleased to be able to offer it to more patients.”

UCLH’s chief executive Professor Marcel Levi: “We will continue to proceed with caution in tightly controlled conditions. Our team of experts will monitor these patients very closely for any signs of response to the treatment.”

This first patient has been receiving treatment for two months and has not experienced any side effects to date. It is too early to determine if, or to what extent, the drug is working at this stage.

UCLH has begun providing the treatment to a second patient. As this patient had the capacity to consent, a legal application was not required.

The Court of Protection today ruled that it was lawful and in the best interests of a third patient to receive the antibody. The patient’s family fully supported UCLH’s application to the court.

For further information please see our media release regarding our first application to the Court of Protection and our Q&A.

 

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