Dr Farooq Rahman

Dr Farooq RahmanTel: 020 3447 9311
Fax: 020 3447 9217
Email: farooq.rahman@uclh.nhs.uk

Location:
University College Hospital

Specialities:
Colorectal service, Endoscopy Unit, Intestinal Failure Service, Gastrointestinal services

Professional background

Farooq Rahman is a Consultant Gastroenterologist at University College Hospital and Honorary Senior Lecturer at University College London. He studied medicine at The Royal Free Hospital School of Medicine in London and completed his specialist training on the North East London rotation. He obtained his PhD from UCL studying the immunopathogenesis of inflammatory bowel disease.

He is a luminal Gastroenterologist with subspecialty interests in inflammatory bowel disease, clinical nutrition & intestinal failure and radiation enteropathy. He also maintains a busy clinical practice and has extensive experience in general gastroenterology and colonoscopy. He maintains a strong commitment to undergraduate/postgraduate teaching and training and training and remains actively involved in clinical and translational research.

Research interests

  • Inflammatory bowel disease: immunopathogenesis
  • Intestinal failure
  • Clinical nutrition
  • Radiation enteropathy

Publications

  • MA Samaan, D de Jong, S Sahami, S Morgan, K Fragkos, S Subramaniam, K Kok, J Makanyanga, I Barnova, H Saravanapavan, I Parisi, S Di Caro, R Vega, FZ Rahman, et al. Incidence and severity of pre-pouch ileitis: A distinct disease entity or a manifestation of refractory pouchitis. Inflamm Bowel Dis. 2016; 22(3): 662-8
  • Y Chen, M Ogundare, CM Williams, Y Wang, GW Sewell, PJ Smith, FZ Rahman, et al. Shotgun cholanomics of ileal fluid. Biochimie. 2013; 95(3): 461-3
  • GW Sewell, YA Hannun, X Han, G Koster, J Bielawski, V Goss, PJ Smith, FZ Rahman, et al. Lipidomic profiling in Crohn’s disease: abnormalities in phosphatidylinositols, with preservation of ceramide, phosphatidylcholine and phosphatidylserine composition. Int J Biochem Cell Biol. 2012; 44(11): 1839-46
  • FZ Rahman, GW Sewell, et al. Defective TNF release from Crohn’s disease macrophages in response to Toll-like receptor activation: relationship to phenotype and genome wide association susceptibility loci. Inflamm Bowel Dis. 2012; 18(11): 2120-7
  • B Hayee, A Antonopoulos, EJ Murphy, FZ Rahman, et al. G6PC3 mutations are associated with a major defect of glycosylation: a novel mechanism for neutrophil dysfunction. Glycobiology. 2011; 21(7): 914-924
  • DJB Marks, PJ Smith, FZ Rahman, et al. Cryptogenic colitis due to occult cytomegalovirus infection. Frontline Gastroenterol. 2011; 2: 57-62
  • S Ghosh, FZ Rahman, et al. Survival following treatment of aorto-esophageal fistula with dual esophageal and aortic intervention. Case Reports in Gastroenterol. 2011; 5(1): 40-44
  • B Hayee, FZ Rahman, et al. The neutrophil respiratory burst and bacterial digestion in Crohn's disease. Dig Dis Sci. 2011; 56(5): 1482-1488
  • FZ Rahman, et al. Henoch Schönlein Purpura complicating adalimumab therapy for Crohn’s disease. World J Gastrointest Pharmacol Ther. 2010; 1(5): 119-122
  • DJB Marks, CR Seymour, GW Sewell, FZ Rahman, et al. Do adaptive or complement immunodeficiencies predispose to inflammatory bowel disease? A critical review. Inflamm Bowel Dis. 2010; 16(11): 1984-1992
  • B Hayee, FZ Rahman, et al. Perspective article: Crohn’s Disease as an Immunodeficiency. Expert Review of Clinical Immunology 2010; 6(4): 585-596
  • FZ Rahman, AM Smith, et al. Delayed resolution of acute inflammation in ulcerative colitis is associated with elevated cytokine release downstream of TLR4. PLoS One 2010; 5(3): e9891
  • DJB Marks, FZ Rahman, GW Sewell, AW Segal. Crohn’s disease: an immune deficiency state. Crit Rev Allergy Immunol. 2010; 38(1): 20-31
  • CD Palmer, FZ Rahman, et al. Multiple PMA-induced macrophage PKC signalling abnormalities in Crohn’s disease. PLoS One 2009; 4(11): e7787
  • FZ Rahman, et al. Impaired macrophage function following bacterial stimulation in chronic granulomatous disease. Immunology 2009; 128(2): 253-259
  • FZ Rahman, AM Smith, et al. Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn’s disease. J Exp Med. 2009; 206(9): 1883-1897
  • R Rajkariar, J. Newson, EK Jackson, P Sawmynaden, A Smith, FZ Rahman, MM Yaqoob, DW Gilroy. Non-resolving inflammation in gp91phox-/- mice, a model for human Chronic Granulomatous Disease, is associated with lower adenosine and cAMP levels. J Immunol. 2009; 182(5): 3262-3269
  • DJB Marks, K Miyagi, FZ Rahman, et al. Inflammatory bowel disease in CGD reproduces the clinicopathological features of Crohn’s disease. Am J Gastroenterol. 2009; 104(1): 117-124
  • FZ Rahman, DJB Marks, et al. Phagocyte dysfunction and Inflammatory bowel disease. Inflamm Bowel Dis. 2008; 14(10): 1443-1452
  • DJ Marks, FZ Rahman, et al. An exuberant inflammatory response to E.coli: implications for the pathogenesis of ulcerative colitis and pyoderma gangrenosum. Gut 2006; 55(11): 1662-1663
  • DJ Marks, M Harbord, R MacAllister, FZ Rahman, et al. Defective acute inflammation in Crohn's disease: a clinical investigation. Lancet 2006; 367(9511): 668-678

GMC/GDC number: 4415819