Dr Mahdad Noursadeghi

Dr Mahdad NoursadeghiTel: 020 3108 2128
Email: mahdad.noursadeghi@uclh.nhs.uk

Location:
University College Hospital

Specialities:
Acute Medical Unit (AMU), Infectious and tropical diseases

Professional background

Current appointments
  • Senior Lecturer in Infection & Immunity, UCL
  • Honorary consultant in Infectious Diseases and General Medicine, UCLH
Previous Appointments
  • 2005-2010: Wellcome Trust Clinician Scientist, Infection & Immunity at UCL
  • 2001 2005: Specialist Registrar in Infectious Diseases & General Medicine, London Deanery
  • 1998 2001: MRC Clinical Research Fellow

Research interests

  • Laboratory research on the mechanisms of human diseases caused by microbial organisms
  • Gene expression profiling in human infectious diseases

Publications

Roe J, Thomas N, Gil E, Best K, Tsaliki T, Morris Jones S, Stafford S, Simpson N, Witt K, Chain B, Miller RF, Martineau A, Noursadeghi M. Blood transcriptomic diagnosis of pulmonary and extrapulmonary tuberculosis. JCI Insight 2016;1(16):e87238. (doi:10.1172/jci.insight.87238). Haas C, Roe J, Pollara G, Mehta M, Noursadeghi M. Diagnostic 'omics' for active tuberculosis. BMC Medicine. 2016 (doi: 10.1186/s12916-016-0583-9).

Byng-Maddick R, Noursadeghi M. Does tuberculosis threaten our ageing populations? BMC Infectious Diseases. 2016 (doi: 10.1186/s12879-016-1451-0).

Marks M, Pollara G, Miller D, Bhatt S, Reynolds C, Gant V, Noursadeghi M. elCID: An electronic Clinical Infection Database to support integrated clinical services and research in infectious diseases. J Infection 2015 (doi: 10.1016/j.jinf.2015.04.007).

Towers G and Noursadeghi M. Interactions between HIV-1 and the Cell-Autonomous Innate Immune System. 2014. Cell Host & Microbe 2014 (doi: 10.1016/j.chom.2014.06.009

Bell L, Pollara G, Pascoe M, Tomlinson GS, Lehloenya RJ, Roe J, Meldau R, Miller RF, Ramsay A, Chain BM, Dheda K, Noursadeghi M. In vivo molecular dissection of the effects of HIV-1 in active tuberculosis. PLoS Pathogens. 2016 (doi: 10.1371/journal.ppat.1005469).

Tomlinson G, Thomas N, Chain BM, Best K, Simpson N, Hardavella G, Brown J, Bhowmik A, Navani N, Janes SM, Miller RF, Noursadeghi M. Transcriptional profiling of endobronchial ultrasound guided lymph node samples aids diagnosis of mediastinal lymphadenopathy. Chest. 2015 (doi: 10.1378/chest.15-0647).

Rasaiyaah J, Tan CP, Fletcher AJ, Price AJ, Blondeau C, Hilditch L, Jacques DA, Selwood DL, James LC, Noursadeghi M*, Towers GJ*. HIV-1 evades innate immune recognition through specific co-factor recruitment. Nature. 2013. (doi: 10.1038/nature12675).

Marks M, Pollock E, Armstrong M, Morris-Jones S, Kidd M, Gothard P, Noursadeghi M, Doherty JF. Needles and the damage done: Reasons for admission and financial costs associated with injecting drug use in a central London teaching hospital. J Infection. 2012. (doi:pii: S0163-4453(12)00290-3. 10.1016/j.jinf.2012.10.004).

Tomlinson GS, Cashmore TJ, Elkington PTG, Yates J, Lehloenya RJ, Tsang J, Brown M, Miller RF, Dheda K, Katz DR, Chain BM, Noursadeghi M. Transcriptional profiling of innate and adaptive human immune responses to mycobacteria in the tuberculin skin test. Eur J Immunol. 2011, (doi:10.1002/eji.201141841).

GMC/GDC number: 4208606