Dr Mark Edwards

Dr Mark Edwards Tel: 020 3448 4295
Email: mark.edwards@uclh.nhs.uk

Location:
National Hospital for Neurology and Neurosurgery

Specialities:
Movement disorders, Neurology and neurosurgery

Professional background

Dr Mark Edwards is a Senior Lecturer at the Sobell Department of Motor Neuroscience and Movement Disorders at the UCL Institute of Neurology and Honorary Consultant Neurologist at the National Hospital for Neurology and Neurosurgery. He graduated in medicine from the Royal London and St Bartholomew’s School of Medicine. He has a BSc in Psychology from the University of London. He did his PhD at the Institute of Neurology with Professor John Rothwell and Professor Kailash Bhatia.

His clinical and research interests are in movement disorders (Parkinson’s disease, atypical Parkinsonism, tremor, dystonia, myoclonus, tics and chorea). He runs specialist outpatient services for movement disorders and has a particular interest in the diagnosis and treatment of dystonia, including focal hand dystonia affecting musicians. He also has a special interest in functional movement disorders and other functional neurological disorders and has a specific clinical service for such patients.

Research interests

  • Pathophysiology and treatment development for Dystonia
  • Tremor, focusing on using electrophysiological techniques to understand mechanism
  • Functional Movement Disorders

Publications

  1. Plazzi G, Pizza F, Palaia V, Franceschini C, Poli F, Moghadam KK, Cortelli P, Nobili L, Bruni O, Dauvilliers Y, Lin L, Edwards MJ, Mignot E, Bhatia KP. Complex movement disorders at disease onset in childhood narcolepsy with cataplexy.Brain. 2011
  2. Stone J, Edwards MJ. How psychogenic are psychogenic movement disorders. Movement Disorders 2011 (in press).
  3. Edwards MJ, Rothwell J. Losing focus: How paying attention can be bad for movement. Movement Disorders 2011 (in press).
  4. Kojovic M, Edwards MJ, Parees I, Rothwell JC, Bhatia KP. Secondary cervical dystonia caused by cerebellar cystic lesion - A case study with transcranial magnetic stimulation. Clin Neurophysiol. 2011 (in press)
  5. Schwingenschuh P, Katschnig P, Saifee TA, Rothwell JC, Bhatia KP, Edwards MJ. Towards a “laboratory supported” level of diagnostic certainty in psychogenic tremor. Movement Disorders 2011 (in press).
  6. Stamelou M, Edwards MJ, Espay A, Fung VS, Hallett M, Lang AE, Bhatia KP. Caveat Spectator: Movement Disorderson YouTube. New England Journal of Medicine 2011
  7. Edwards MJ, Moretto G, Schwingenschuh P, Katschnig P, Bhatia KP, Haggard P. Abnormal sense of intention preceding voluntary movement in patients with psychogenic tremor. Neuropsychologia 2011
  8. Parees I, Saifee TA, Kassavetis P, Kojovic M, Rubio-Agusti I, Rothwell JC, Bhatia KP, Edwards MJ. Believing is Perceiving: Mismatch between self-report and actigraphy in psychogenic tremor. Brain 2011 (in press)
  9. Stamelou M, Edwards MJ, Hallett M, Bhatia KP. The non-motor syndrome of primary dystonia. Brain 2011 (in press)
  10. Van Poppelen D, Saifee TA, Schwingenschuh P, Katschnig P, Tijssen M, Bhatia KP, Edwards MJ. Attention to Self in Psychogenic Tremor. Movement Disorders 2011 (in press)
  11. Edwards MJ, Lang AE Bhatia KP. Stereotypies: a critical appraisal and a suggestion of a clinically useful definition. Movement Disorders 2011 (in press)
  12. Sadnicka A, Hoffland BS, Bhatia KP, van de Warrenberg BP, Edwards MJ. The Cerebellum in Dystonia – help or hindrance? Clinical Neurophysiology 2011 (in press)
  13. Edwards MJ, Alonso-Canovas A, Schrag A, Bloem B, Thompson PD, Bhatia KP. Limb amputations in fixed dystonia: a form of body integrity identity disorder? Movement Disorders 2011 (in press).
     
  14. Mir P, Trender-Gerhard I, Edwards MJ, Schneider S, Bhatia KP, Jahanshahi M. Motivation and movement: the impact of monetary incentive on performance speed. Experimental Brain Research 2011 (in press)
     
  15. Kassavetis P, Hoffland B, Saifee TA, Bhatia KP, van de Warrenburg BP, Rothwell JC, Edwards MJ. Cerebellar brain inhibition is decreased in active and surround muscles at the onset of voluntary movement. Experimental Brain Research 2011 (in press)
     
  16. Edwards MJ, Cordivari C, Bhatia KP. Dramatic immediate response to botulinum toxin injections in patients with fixed dystonia. Movement Disorders 2011 (in press)
     
  17. Talelli P, Hoffland BS, Schneider SA, Edwards MJ, Bhatia KP, van de Warrenburg BP, Rothwell JC. A distinctive pattern of cortical excitability in patients with the syndrome of dystonia and cerebellar ataxia. Clin Neurophysiol. 2011;122(9):1816-9.
     
  18. Kojovic M, Caronni A, Bologna M, Rothwell JC, Bhatia KP, Edwards MJ. Botulinum toxin injections reduce cortical plasticity in patients with primary dystonia. Movement Disorders 2011 (in press)
     
  19. Hoffland B, Snik D, Bhatia KP, Schwingenschuh P, Crutch S, van de Warrenberg BP, Edwards MJ. Patients with cervical dystonia have discrete deficits in praxis. JNNP 2011 (in press)
     
  20. Damasio J, Edwards MJ, Alonso-Canovas A, Schwingenschuh P, Kagi G, Bhatia KP. The clinical phenomenon of primary tic disorder associated with dystonia: a large clinical series and review of the literature. Movement Disorders 2011 (in press)
     
  21. Alonso-canovas, A., Katschnig, P., Tucci, A., Carecchio, M., Wood, N. W., Edwards, MJ., Martínez Castrillo, J. C., Burke, D., Heales, S., Bhatia, K. P. Atypical parkinsonism with apraxia and supranuclear gaze abnormalities in type 1 Gaucher disease. Expanding the spectrum: case report and literature review Movement Disorders 2010; 25(10), 1506-1509
     
  22. Schwingenschuh P, Edwards MJ, Katschnig P, Rothwell JC, Bhatia KP. The blink reflex recovery cycle differs between essential and presumed psychogenic blepharospasm. Neurology 2010
     
  23. Snik D, Sofie Hoffland B, Aguirregomozcorta M, Schwingenschuh P, Bhatia KP, van de Warrenberg BP, Edwards MJ. Validation of a dystonia screening Questionnaire: testing in a cohort of mixed neurological disorders. Parkinsonism Relat Disord 2010;16(9):620-622.
     
  24. Kaschnig P, Edwards MJ, Schwingenschuh P, Aguirregomozcorta M, Kagi G, Rothwell JC, Bhatia KP. Mental rotation of bodyparts and sensory temporal discrimination in fixed dystonia. Mov Disord 2010, 25:1061-7
     
  25. Schwingenschuh P, Ruge D, Edwards MJ, Terranova C, Katschnig P, Carrillo F, Silvera-Moriyama L, Schneider S, Kagi G, Palomar FJ, Talelli P, Dickson J, Lees AJ, Quinn NP, Mir P, Rothwell JC, Bhatia KP. Distinguishing SWEDDs patients with asymmetric tremor from Parkinson’s disease: A clinical and electrophysiological study. Mov Disord 2010;25:560-9.
     
  26. Houlden H, Schneider SA, Paudel R, Melchers A, Schwingenschuh P, Edwards M, Hardy J, Bhatia KP. THAP1 mutations (DYT6) are an additional cause of early-onset dystonia. Neurology 2010;74:846-850.
     
  27. Esposito M, Edwards MJ, Bhatia KP, Brown P, Cordivari C. Idiopathic spinal myoclonus: a clinical and neurophysiological disorder of uncertain origin. Mov Disord. 2009;24(16):2344-9.
     
  28. Trender-Gerhard I, Sweeney MG, Schwingenschuh P, Mir P, Edwards MJ, Gerhard A, Polke JM, Hanna MG, Davis MB, Wood NW, Bhatia KP. Autosomal-dominantGTPCH1-deficient DRD: clinical characteristics and long-term outcome of 34 patients. J Neurol Neurosurg Psychiatry. 2009; 80(8):839-45.
     
  29. Foltynie T, Cheeran B, Williams-Gray CH, Edwards MJ, Schneider S, Weinberger DR, Rothwell J, Barker RA, Bhatia KP. BDNF val66met Influences Time To Onset Of Levodopa-Induced Dyskinesia In Parkinson's Disease. J Neurol Neurosurg Psychiatry. 2009;80(2):141-4