Dr Mary Falzon

Dr Mary FalzonTel: 020 7679 6025
Email: mary.falzon@uclh.nhs.uk

Location:
University College Hospital

Specialities:
Cellular Pathology – Cytopathology , Histopathology, Cellular pathology, Pathology

Professional background

I trained at The Middlesex Hospital Medical School, London and qualified in 1981. My pathology training started at The Middlesex Hospital, initially as an assistant Lecturer in pathology and then as Lecturer to the joint Middlesex and UCLH histopathology departments.

In 1990 I was appointed Consultant at Ealing Hospital in both Histopathology and Cytopathology. There I took the Lead for Cytopathology and Breast histopathology and established a very successful one stop breast clinic.

In 2000 I was appointed Consultant at UCLH, with responsibility in both Histopathology and Cytology. I was appointed the Clinical Head of service in 2004.

I became the Medical lead for London Quality Assurance Reference Centre in 2005 and scheme organiser for the gynaecological cytology EQA for London’s 23 laboratories. I chair various committees, meetings, and Quality Assurance visits to Trusts.

I became a member on the Local Negotiating Committee in 2006.

In 2007 I led the formation of the joint Royal Free and UCLH cervical cytology screening unit based at UCLH serving women in Camden and Islington.

In 2008 I led the successful joint venture with the independent sector for UCLH to provide laboratory and clinical leadership for histology and diagnostic cytology for Ealing hospital.

In 2009 I was appointed Divisional Director for Pathology.

Research interests

I am the Lead for breast and pulmonary pathology and sit on both tumour Boards for the North London Cancer Network. I am the HER2 Lead for the NLC network and responsible for the Her2 immunocytochemistry and FISH reporting service to many hospitals in the UK and abroad.

At UCLH we were one of the first centres to provide an intraoperative service for assessment of sentinel nodes using touch imprint cytology. The joint unit with Barts and The London will provide a first class breast service to our patients.

With the acquisition of the Heart Hospital by UCLH we have a large lung pathology practice dealing with both cancer and interstitial lung disease serving UCLH ad other hospitals.

My NHS duties include responsibility for various MDMs, supervising trainee pathologists and performing post-mortem examinations.

I have commitments to undergraduate teaching, mentor medical students and interview prospective medical students. I also lecture to postgraduates on sentinel lymph nodes and Her 2 testing.

I have had a long interest in EQA and I am one of the founding members of the North Thames Histopathogy EQA committee. I take part in the general histopathology and breast specialist and lung EQA scheme.

Publications

Publications: 

Tung KT, Woolf A, Falzon M. Prostatic involvement in Wegener’s Granulomatosis. Postgrad Med J (1987);63:53 54.

Vaira D, Holton J, Cairns S, Falzon M, Salmon PR. 4 Hour Rapid Urease Test (RUT) for the Detection of Campylobacter Pylori (CP): is it reliable enough to start therapy?  J Clin Pathol, 1988; 41:355 56.

Costa DC, Glynne Jones R, Falzon M, Lui D, Ryder JP, Ell P J. 99Tcm Pentavalent DMSA Imaging Detects Metastases of Poorly Differentiated Carcinoma of the Thyroid.  Clin Nuc Med, (1989); 14:218 221.

Vaira D, Holton J, Falzon M, Polydorou A, Cairns SR, Dowset JF, Salmon PR. Decreased Antibody Titres to Campylobacter Pylori (CP) After Treatment of Gastritis.  BMJ, (1988); 6thAug:297.

Vaira D, Holton J, Cairns SR, Falzon M, Polydorou A, Dowsett JF, Salmon PR. Urease Tests for Campylobacter Pylori (CP): care in Interpretation.  J Clin Pathol,(1988); 41:812 813.

Vaira D, Holton J, Falzon M, Cairns SR, Dowsett J, Polydorou A, Salmon PK. Investigation of Campylobacter pylori Associated Gastritis by Histology, Culture, Urease Tests, Brushings and Antibody Level. Italian Journal of Pathology, (1988); 20:299 304.

Falzon M, Isaacson PG. Histological Classification of the Non Hodgkin’s Lymphomas.  Blood Reviews, (1990); 4:111 115.

Vaira D, Holton J, Osborne J, Falzon M, D’Anna L, Romanos A, McNeil I. Endoscopy in Dyspeptic Patients: Is Gastric Mucosal Biopsy Useful?  American Journal of Gastroenterology.(1990); 85; 6:701-704.

Sagar SM, Karp SJ, Falzon M. Malignant Lymphomatous Polyposis: Diagnosis and Response to Chemotherapy. Clinical Oncology.(1990); 2:230-234.

Falzon M, Isaacson PG. The natural history of Benign Lympho epithelial lesion of the salivary gland in which there is a monoclonal population of B cells. A report of two cases.  Am J Surg Path. (1991); 15(1):59-65.

Wotherspoon AC, Ortiz-Hidalgo C, Falzon M, Isaacson PG. Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma. Lancet. (1991); 338: 1175-76.

Hampson SJ, Fowlis GF, Chapple CR, Falzon M and Worth PH. Extra-Renal adult Wilm’s Tumour: Presentation, Diagnosis and Management. Br J Urol. (1992)

Gelister JSK, Falzon M, Crawford R, Chapple CR and Hendry WF. Urinary Tract Metastasis from Renal Carcinoma. Br J Urol. (1992); 69:250-252.

Hampson SJ, Falzon M and Cowie AG. Intestinal Metaplasia of the Bladder: Implications for Management. Br J Urol. (1992); 69:323-324.

Varia D, Holton J, Ainley C, Falzon M, Osborne J, Romanos A, Chandrakumaran K, McNeil I. Double Blind Trial of Colloidal Bismuth Subcitrate vs Placebo in Helicobacter Pylori positive patients with non ulcer dyspepsia. Ital-J Gastro-enterol, 1992. Sept. 24 (7):400-4.

Smith DJ, Hamdy FC, Falzon M, Evans JWH and Chapple CR. Paget’s Disease of  the Glans

 Penis: An Unusual Urological Malignancy.   European Urology (1994); 25:316-319

Leung HY, Cooper S, Razak AH, Falzon M, Abel P. Ureteric filling defect. Postgrad Med J 1996;72:

W Svensson, P Forouhi, J Lynn and Falzon M .Differences of vascular pattern demonstrated by colour Doppler ultrasound allows differentiation of fibroadenomas from cancers. The European Journal of Ultrasound 1999

Satoh F. Beak SA. Small CJ. Falzon M. Ghatei MA. Bloom SR. Smith DM. Characterization of human and rat glucagon-like peptide-1 receptors in the neurointermediate lobe: lack of coupling to either stimulation or inhibition of adenylyl cyclase. Endocrinology. 141(4):1301-9, 2000 Apr.

S Iqbal, M Falzon, R T Mathie, R C N Williamson and A K Kakkar. Thrombomodulin Expression of Primary Breast Cancer Tissue is a Predictor of Axillary Lymph Node Metastasis. . Thrombosis and Haemostasis 1999; 833-834

Vaidya JS, Hall-Craggs MA, Baum M, Tobias JS, Falzon M, D’Souza DP, Morgan S

Percutaneous Minimally Invasive Stereotactic Primary Radiotherapy. Lancet Oncology3(4) 252-3,         2002

AC Lee, DW Chicken, CDO Pickard, GM Briggs, G Kocjan, M Falzon, I Bigio, PJ Ell, JR      Sainsbury, MRS Keshtgar and SG Bown. Comparative study of Elastic Scattering Spectroscopy and touch print cytology in assessing Sentinel Lymph Node status in Breast Cancer. British Journal of Surgery 90:112-112, 2003

al-Adnani M, Etessami N, Freeman A, Falzon M. Why abolish C3? Cytopathology 2003,14 ,302-4

D Ravichandra, G Kocjan, M Falzon,  RY Ball , DNL Ralphs . Imprint cytology of the sentinel lymph node in the assessment of axillary node status in breast carcinoma. European Journal of Oncology (2004) 30, 238-242

Kristie S Johnson, Dennis W Chicken, David CO Pickard, Andrew C Lee, Gavin Briggs, Mary Falzon, Irving J Bigio, Mohammed R Keshtgar and Stephen G Bown. Elastic Scattering for intraoperative determination of sentinel lymph  Node Status in the Breast. Journal of Biomedical Optics (96 ) 2004 Nov-Dec;9(6):1122-8 

DW Chicken, G Kocjan, M, M Falzon, AC Lee,M.Douek, JR Sainsbury  and MRS  Keshtgar.  Intra-      Operative touch imprint cytology for the diagnosis of  Sentinel Lymph Node metastases in Breast Cancer-  British Journal of Surgery 2006;93: 572-576-----Original Article

Lai CS, Boshoff C, Falzon M, Lee SM. Complete Response to Erlotinib Treatment in Brain Metastases from Recurrent Non Small Cell Lung Cancer . Thorax. 2006 Jan;61(1):91

Jeremy George P, Banerjee,AK, Read CA, O’ Sullivan C,  Falzon M, Pezzella F, Nicholson AG, Shaw P, Laurent G,  Rabbitts PH.. Surveillance for detection of early lung cancer in patients with bronchial dysplasia. Accepted  Thorax.2007 Jan, 62(1) 43-50 Original Paper

Goodman, Anna, Falzon Mary, Gelder Colin and George, Jeremy. Central airway obstruction by a peripheral hamartoma. Lung Cancer 2007, Apr 27

Joanna C Porter, Mary Falzon and Adam Hall. Polarised Localisation of Epithelial CXCL11 in Chronic Obstructive Pulmonary Disease and Mechanisms of T Cell Egression. The Jounal of Immunology 2008, 180: 1866-1877

M Loddo, SR Kingsbury, M Rashid, I Proctor, C Holt, J Young, S EL-Sheikh, M  Falzon, K.L Eward, T Prevos, R Sainsbury, K Stoeber and GH Williams. Cell-Cycle-phase progression analysis identifies unique phenotypes of major prognostic and predictive significance in breast cancer. Accepted by Br J Cancer 2009 Mar 24;100(6):959-70

GMC/GDC number: 2700728