Dr Nicola Ambrose

Dr Nicola AmbroseTel: 020 3447 9215
Fax: 020 3447 9278
Email: uclh.rheumatology@nhs.net

Location:
University College Hospital

Specialities:
Adolescent and young adult rheumatology, Rheumatology

Professional background

Dr Nicola Ambrose joined the UCLH team is a consultant rheumatologist in 2014. Her clinical interests include adolescent and adult rheumatology, vascular biology, connective tissue disorders and chronic pain.

She was awarded a Clinical Research Fellowship from the Royal College of Physicians Ireland and subsequently a Junior Fellowship from Arthritis Research UK, to undertake a PhD at Imperial College London. Her PhD was awarded for research into abnormal inflammation in Behçet’s Syndrome. She then moved to UCLH in 2013 to undertake a clinical fellowship in adolescent rheumatology(Richard Steeven’s Scholarship recipient), before joining the department permanently as a consultant. She holds an honorary contract at UCL and Imperial College London.

She is regularly involved in teaching medical students, junior doctors and allied health professionals.

Research interests

  • Adolescent Rheumatology
  • Vascular Biology and Connective Tissue Disorders

Publications

1: Ambrose N, Khan E, Ravindran R, Lightstone L, Abraham S, Botto M, Johns M, Haskard D. The exaggerated inflammatory response in behçet's syndrome: Identification of dysfunctional post-transcriptional regulation of the IFNγ/CXCL10 (IP-10) pathway. Clin Exp Immunol. 2015 May 18. doi: 10.1111/cei.12655. [Epub ahead of print] PubMed PMID: 25982097.

 2: Thornton CC, Ambrose N, Ioannou Y. Ofatumumab: a novel treatment for severe systemic lupus erythematosus. Rheumatology (Oxford). 2015 Mar;54(3):559-60. doi: 10.1093/rheumatology/keu475. Epub 2014 Dec 24. PubMed PMID: 25539826.

3: Mehta P, Ambrose N, Haskard DO. Work-related disability in Behçet's syndrome: a British case series. Clin Exp Rheumatol. 2014 Jul-Aug;32(4 Suppl 84):S173-4. Epub 2014 Jul 8. PubMed PMID: 25005835.

4: Ambrose N, Pierce IT, Gatehouse PD, Haskard DO, Firmin DN. Magnetic resonance imaging of vein wall thickness in patients with Behçet's syndrome. Clin Exp Rheumatol. 2014 Jul-Aug;32(4 Suppl 84):S99-102. Epub 2014 Sep 30. PubMed PMID: 25268665.

5: Ambrose NL, Haskard DO. Differential diagnosis and management of Behçet syndrome. Nat Rev Rheumatol. 2013 Feb;9(2):79-89. doi: 10.1038/nrrheum.2012.156. Epub 2012 Sep 25. Review. PubMed PMID: 23007742.

6: Boyle JJ, Johns M, Lo J, Chiodini A, Ambrose N, Evans PC, Mason JC, Haskard DO. Heme induces heme oxygenase 1 via Nrf2: role in the homeostatic macrophage response to intraplaque hemorrhage. Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2685-91. doi: 10.1161/ATVBAHA.111.225813. PubMed PMID: 21868703.

7: Ambrose NL, Kearns G, Mohammad A. Male lupus: a diagnosis often delayed--a case series and review of the literature. Ir J Med Sci. 2011 Mar;180(1):279-82. doi: 10.1007/s11845-009-0438-x. Epub 2009 Oct 28. Review. PubMed PMID: 19862568.

8: Ambrose NL, Keogan F, O'Callaghan JP, O'Connell PG. Obesity and disability in the symptomatic Irish knee osteoarthritis population. Ir J Med Sci. 2010 Jun;179(2):265-8. doi: 10.1007/s11845-009-0459-5. Epub 2010 Jan 7. PubMed PMID: 20054661.

9: Mohammad AF, Ambrose N, Hamnvik OP, Kearns G. Meticillin-sensitive Staphylococcus aureus costochondritis in a healthy man. Nat Rev Rheumatol. 2009 Dec;5(12):708-10. doi: 10.1038/nrrheum.2009.216. PubMed PMID: 19946297.

10: Ambrose NL, Cunnane G. Importance of full evaluation in patients who complain of neck pain. Ir J Med Sci. 2009 Jun;178(2):209-10. doi: 10.1007/s11845-008-0256-6. Epub 2009 Jan 8. PubMed PMID: 19129980.

11: Ambrose NL, Tobin AM, Howard D. Etanercept treatment in Sweet's syndrome with inflammatory arthritis. J Rheumatol. 2009 Jun;36(6):1348-9. doi: 10.3899/jrheum.080698. PubMed PMID: 19509095.

12: Ambrose NL, O'Connell P, Kearns G. Limiting cardiovascular risk in Irish rheumatoid arthritis patients. Ir J Med Sci. 2009 Mar;178(1):53-5. doi: 10.1007/s11845-008-0252-x. Epub 2008 Nov 13. PubMed PMID: 19005635.

13: Cusack C, Danby C, Fallon JC, Ho WL, Murray B, Brady J, O'Kelly P, Ambrose N, Kearns G, Murphy GM. Photoprotective behaviour and sunscreen use: impact on vitamin D levels in cutaneous lupus erythematosus. Photodermatol Photoimmunol Photomed. 2008 Oct;24(5):260-7. doi: 10.1111/j.1600-0781.2008.00373.x. PubMed PMID: 18811868.

14: Mohammad A, Ambrose N, Tuohy M, Conway R, Costello R, Kearns G. Relapsing polychondritis: reversible airway obstruction or asthma. Clin Exp Rheumatol. 2008 Sep-Oct;26(5):938-40. PubMed PMID: 19032834.

15: Ambrose N, Smith D, Cunnane G. The importance of diagnosing neck pain. Clin Rheumatol. 2008 Aug;27(8):1061-2. doi: 10.1007/s10067-008-0863-7. Epub 2008 Mar 21. PubMed PMID: 18357501.

16: Ambrose NL, O'Connell PG. Anti-TNF alpha therapy does not always protect rheumatoid arthritis patients against developing pericarditis. Clin Exp Rheumatol. 2007 Jul-Aug;25(4):660. PubMed PMID: 17888231.

GMC/GDC number: 7057343