Prof Olga Ciccarelli

Dr Olga CiccarelliTel: 020 3448 3419
Fax: 0207 813 6505

National Hospital for Neurology and Neurosurgery


Professional background

Prof Olga Ciccarelli is Professor of Neurology at University College London’s (UCL) Institute of Neurology with a particular interest in Multiple Sclerosis. Olga studied at the University of Rome, completing her training in Neurology in 1999.
After coming to the UK, she obtained a PhD in Neurological Studies at the Institute of Neurology in 2005. She was then awarded the prestigious Wellcome Trust Advanced Clinical Fellowship. She became Professor of Neurology in 2014. 
Prof Ciccarelli is the Head of the NMR Research Unit, Queen Square MS Centre, and leads in research studies in MS using magnetic resonance imaging (MRI). She also teaches postgraduate students and attracts funding for research. She is an Associate Editor of Neurology, which is the official journal of the American Academy of Neurology.

Research interests

  • Multiple Sclerosis
  • Brain and spinal cord imaging
  • Clinical trials
  • Autoimmune diseases with brain involvement


Abdel-Aziz K, Schneider T, Solanky BS, Yiannakas MC, Altmann DR, Wheeler-Kingshott CA, Peters AL, Day BL, Thompson AJ, Ciccarelli O. Evidence for early neurodegeneration in the cervical cord of patients with primary progressive multiple sclerosis. Brain. 2015
Tur C, Ramagopalan S, Altmann DR, Bodini B, Cercignani M, Khaleeli Z, Miller DH, Thompson AJ, Ciccarelli O. HLA-DRB1*15 influences the development of brain tissue damage in early PPMS. Neurology. 2014 Nov 4;83(19):1712-8.  
Ciccarelli O, Barkhof F, Bodini B, De Stefano N, Golay X, Nicolay K, Pelletier D, Pouwels PJ, Smith SA, Wheeler-Kingshott CA, Stankoff B, Yousry T, Miller DH. Pathogenesis of multiple sclerosis: insights from molecular and metabolic imaging. Lancet Neurol. 2014 Aug;13(8):807-22.  

Ciccarelli O, Thomas DL, De Vita E, Wheeler-Kingshott CA, Kachramanoglou C, Kapoor R, Leary S, Matthews L, Palace J, Chard D, Miller DH, Toosy AT, Thompson AJ.Low myo-inositol indicating astrocytic damage in a case series of neuromyelitis optica. Ann Neurol. 2013 Aug;74(2):301-5.

Ciccareilli O, Catani M, Johansen-Berg, H. Calrk C, Thompson A. (2008). Diffusion-based tractography in neurological disorders: concepts, applications and future developments.  Lancet Nerurol, 7 (8), 715-27.

Ciccarelli O, Wheeler-Kingshott CA. McLean MA< Cercignani M, WimpeyK, Miller DH, Thompson AJ (2007) Spinal cord spectroscopy and diffusion-based tractography to assess acute disability in MS.  Brain 130(8), 2220-2231.

Ciccarelli O, Behrens TE, Altmann DR, Orrell RW, Howard RS, Johansen-BergH, Miller DH, Matthews PM, Thompson AJ (2006) Probabilistic diffusion tractography; a potential tool to assess the rate of disease progression amyotrphic lateral sclerosis. Brain 129(7), 1859-18-71.

Behrens TEJ, Johansen-BergH, Woolrich MW, Smith SM, Wheeler-KingshottCAM, Boulby PA, Barker GJ, Sillery EL, SheehanK, Ciccarelli O, Thompson AJ, BradyJM, Matthews PM (2003).  Non invasive mapping of connections between human thalamus and cortex using difussion imaging.  Nature Neuroscience 6 (7) 750-757.

Brex PA, Ciccarelli O, O'Riordan JI, Sailer M, Thompson AJ, Miller DH< (2002).  A longtiduinal suty of abnormalities on MRI and disability from MS. New England Journal of Medicine 346(3), 158-164.

GMC/GDC number: 4686365