Dr Pascal Meier

Dr Pascal MeierTel: 020 3456 6029
Email: pascal.meier@uclh.nhs.uk

Heart Hospital

General and Interventional cardiology

Professional background

Pascal Meier is a consultant cardiologist at the Heart Hospital and UCLH, He is leading the Yale - UCL Device Development Programme (http://yale-ucl.org/index.aspx). He trained at the University Hospital Bern, Switzerland, and has completed an MD at the University of Bern.  He completed his clinical and research training at the University of Michigan Medical Center in the United States. He is experienced in all aspects of adult cardiology and has a main focus on percutaneous coronary interventions (including rotational atherectomy, intravascular physiological measurements (FFR) and intravascular imaging).

Research interests

His research interests include the evaluation of new technologies in interventional Cardiology.

Further research interests are sudden cardiac death and the coronary collateral circulation (growth of new vessels in the heart).

He is an associate editor of the Cardiology journal "heart". He is a member of the British Cardiovascular Intervention Society BCIS.


For a complete and updated list, please see: http://www.drpascalmeier.com

Selected publications:

Pascal Meier, Harry Hemingway, Alexandra J Lansky, Guido Knapp, Bertram Pitt, Christian Seiler. The Impact of the Coronary Collateral Circulation on Mortality: A Meta-Analysis. Eur Heart J (in press) [IF 10.1]

Mario Togni*, Steffen Gloekler*, Pascal Meier*, Stefano F. de Marchi, Tobias Traupe, Hélène Steck, Tobias Rutz, Christian Seiler. Instantaneous Coronary Collateral Function During Supine Bicycle Exercise – A Randomized Controlled Crossover Trial. Eur Heart J, 2010; 10;5(6):e11040)  [IF 10.1] 

Steffen Gloekler*, Pascal Meier*, Stefano F. de Marchi, Tobias Traupe, Stefano Rimoldi, Kerstin Wustmann, Hélène Steck, Stéphane Cook, Rolf Vogel, Mario Togni, Christian Seiler. Myocardial Salvage Through Coronary Collateral Growth by External Counterpulsation: A Controlled Randomized Trial. Heart, 2010; 96:202-207  [IF 4.7]

Timir S Baman, Pascal Meier, Joshua Romero, Lindsey Gakenheimer, James N Kirkpatrick, Patricia Sovitch, Hakan Oral, Kim A Eagle. Safety of Pacemaker Reutilization: A Meta-Analysis with Implications for Underserved Nations. Circulation: Arrhythmia and Electrophysiology, 2011 [IF 4.8]

Stefano F. de Marchi, Steffen Gloekler, Pascal Meier, Tobias Traupe,  Hélène Steck, Stéphane Cook, Rolf Vogel, Christian Seiler. Determinants of Preformed Collateral Vessels in the Human Heart without Coronary Artery Disease. Cardiology 2011;118(3):198-206 [IF 2.0]

Andreas Indermuehle, Rolf Vogel, Pascal Meier, Rainer Zbinden, Christian Seiler. Myocardial Blood Volume and Coronary Resistance During and After Coronary Angioplasty. Am J Physiol, Jan 7, 2011 [IF 3.9] 

Rainer Zbinden, Ursula Wenger, Pascal Meier, Steffen Gloekler, Stephan Windecker, Bernhard Meier, Christian Seiler. Silent Ischemia Normalized for Coronary Collateral Function in Patients with and without Diabetes. Int J Cardiol, Jan 5, 2011.

Tobias Rutz, Steffen Gloekler, Stefano F de Marchi, Tobias Traupe, Pascal Meier, Parham Eshtehardi, Ste´phane Cook, Rolf Vogel, Paul Mohacsi, Christian Seiler. Coronary Collateral Function in the Transplanted Heart: Propensity Score Matching with Coronary Artery Disease. Heart, 2011; Apr;97(7):557-63 

Patric Froesch, Michele Martinelli, Pascal Meier, Stéphane Cook, Stephan Windecker, Roger Hullin, Paul Mohacsi, Bernhard Meier. Clinical Use of Temporary Percutaneous Left Ventricular Assist Devices. Cath Cardiovasc Interv, 2011 Aug 1;78(2):304-13.

Yvonne Strahm, Annina Flueckiger, Michael Billinger, Pascal Meier, Daniel Mettler, Susan Weisser, Thomas Schaffner, Otto M. Hess. Endothelial-cell-binding aptamere for coating of intracoronary stents . J Invasive Cardiol, 2010; Oct;22(10):481-7 

Steffen Gloekler, Tobias Traupe, Pascal Meier, Helene Steck, Stefano de Marchi, Christian Seiler. Diagnostic coronary balloon occlusion in normal arteries: an angiographic and clinical follow-up study. Am J Cardiol, 2010; 15;105(12):1716-22. 

Pascal Meier, Paul Baker, David Jost, Ian Jacobs, Bettina Henzi, Guido Knapp, Comilla Sasson. Chest Compressions Before Defibrillation for Out-of-Hospital Cardiac Arrest: A Meta-Analysis of Randomized Controlled Clinical Trials. BMC Medicine, 2010;  8:52 [Impact Factor IF 5.7]

Pascal Meier, Emanouil Brilakis, Roberto Corti, Guido Knapp, Hitinder Gurm. Drug eluting versus bare metal stents for saphenous vein graft interventions– a meta-analysis. PLoS ONE, 2010; 10;5(6):e11040. [IF 4.4]

Pascal Meier, Hitinder S Gurm. Is simpler really better? Single bolus sodium bicarbonate to prevent contrast-induced nephropathy. Am J Cardiol, 2010; 104 (7): 921-25 (Scientific letter) [IF 3.6]

Pascal Meier, Guido Knapp, Umesh Tamhane, Seemant Chaturvedi, Hitinder Gurm. Carotid endarterectomy versus carotid stenting for carotid stenosis and long-term results. A meta-analysis of randomized controlled clinical trials. British Medical Journal, 2010 Feb 12 2010;340:c467 [IF 13.7] 

Pascal Meier, Steffen Gloekler, Stefano de Marchi, Rainer Zbinden, Etienne Delacrétaz, Christian Seiler. An Indicator of Sudden Cardiac Death During Brief Coronary Occlusion: ECG QT Time and the Role of Collaterals. Eur Heart J 2010, 31(10): 1197-1204 [IF 10.1]

Pascal Meier, Steffen Gloekler, Stefano de Marchi, Andreas Indermühle, Tobias Rutz, Tobias Traupe, Rolf Vogel, Christian Seiler. Myocardial Salvage Through Coronary Collateral Growth by Granulocyte-Colony Stimulating Factor in Chronic Coronary Artery Disease: A Controlled Randomized Trial. Circulation, 2009;120:1355-1363 [IF 14.4]

Pascal Meier, Dennis T. Ko, Akira Tamura, Umesh Tamhane, Hitinder S. Gurm. Sodium bicarbonate for the prevention of contrast-induced nephropathy: A meta-analysis. BMC Medicine, 2009, 7:23 [IF 5.7]

Pascal Meier, Janine Antonov, Rainer Zbinden, Alexandre Kuhn, Stephan Zbinden, Steffen Gloekler, Mauro Delorenzi, Rolf Jaggi, Christian Seiler. Non-Invasive Gene-Expression-Based Detection of Well Developed Collateral Function in Individuals With and Without Coronary Artery Disease. Heart 2009; 95: 900-908. [IF 4.7] 

Andreas Indermuehle, Rolf Vogel, Tobias Rutz, Pascal Meier, Christian Seiler. Myocardial Contrast Echocardiography for the Distinction of Hypertrophic Cardiomyopathy from Athlete’s Heart at Rest and Hypertensive Heart Disease. Swiss Med Wkly, 2009;139(47-48):691-8.

Micheal Reed, Pascal Meier, Umesh Tamhane, Kathy B Welch, Mauro Moscucci, Hitinder S. Gurm. The relative renal safety of iodixanol compared with low-osmolar contrast media: a meta-analysis of randomized controlled trials. JACC Cardiovasc Interv, 2009; 2(7): 645-54. 

Umesh Tamhane, Pascal Meier, Stanley Chetcuti, Kang-Yin Chen, Seung-Woon Rha, Michael-P. Grossman, Hitinder Gurm. Efficacy of Cilostazol in reducing restenosis in patients undergoing contemporary sent based PCI: a meta-analysis of randomized controlled trials, EuroIntervention, 2009; 5(3): 384-93 

Hitinder Gurm, Umesh Tamhane, Pascal Meier, Stanley Chetcuti, Michael Grossman, Eric Bates. GpIIbIIIa antagonists for primary PCI- a meta-analysis. Circulation: Cardiovascular Interventions, 2009; 2: 230-236 

Annina Flueckiger, Daniel Mettler, Yvonne Strahm, Urs Studer, Michael Billinger, Thomas Schaffner, Pascal Meier, Otto M. Hess. Intimal Proliferation and Restenosis in Paclitaxel-Eluting Stents with Aminoparylene as Carrier Substance in Swine. J Invasive Cardiol, 2009; 21(3):128-32.

Rolf Vogel, Andreas Indermühle, Meier Pascal, Christian Seiler. Quantitative stress echocardiography in coronary artery disease using contrast-based myocardial blood flow measurements: prospective comparison with coronary angiography. Heart, 2009; 95(5): 377-84. 

Daniel Stalder, Trinh Cung, Steffen Gloekler, Pascal Meier, Evelyn Schlappritzi, André Haeberli, Santica Marcovina, Christian Seiler, Manfred Heller. Apolipoprotein(a) Size and Lipoprotein(a) Concentrations in Patients with Good and Poor Coronary Collateral Flow – an Interrelation Discovered by Proteomic Screening of Pooled Plasma Samples. J Proteomics Bioinform, 2008; 389-400. 

Daniela Frey, Michael Billinger, Meier Pascal, Olgica Beslac, Raphael Grossenbacher, Otto M. Hess. Endothelialization of sirolimus-eluting stents with slow and extended drug release in the porcine overstretch model. J Invasive Cardiol, 2008; 20(12): 631-4.

Yara Banz, Robert Rieben, Claudia Zobrist, Pascal Meier, Sidney Shaw, Jonas Lanz, Thierry Carrel, Pascal Berdat. Addition of dextran sulfate to blood cardioplegia attenuates reperfusion injury in a porcine model of cardiopulmonary bypass. Eur J Cardiothoracic Surgery, 2008; 34 (3): 653-660 

Pascal Meier, Rainer Zbinden, Mario Togni, Peter Wenaweser, Stephan Windecker, Bernhard Meier, Christian Seiler. Coronary collateral function long after drug-eluting stent implantation. J Am Coll Cardiol, 2007; 49 (1): 15-20 [IF 12.5]

Pascal Meier, Steffen Gloekler, Rainer Zbinden, Sarah Beckh, Stephan Zbinden, Kerstin Wustmann, Michael Billinger, Rolf Vogel, Stéphane Cook, Peter Wenaweser, Mario Togni; Stephan Windecker; Bernhard Meier; Christian Seiler. The Beneficial Effect of Recruitable Collaterals: a 10-Year Follow-up Study in Patients with Stable Coronary Artery Disease Undergoing Quantitative Collateral Measurements. Circulation, 2007; 116(9): 975-83 [IF 14.4]

Rainer Zbinden *, Stephan Zbinden *, Pascal Meier *, Damian Hutter , Michael Billinger , Andreas Wahl , Jean-Paul Schmid , Stephan Windecker , Bernhard Meier , Christian Seiler. Coronary collateral flow in response to endurance exercise training. Eur J Cardiovasc Prev Rehabil, 2007;14 (2): 250-7 [IF 2.6]

Yara Banz, Otto M Hess, Simon C Robson, Eva Csizmadia, Daniel Mettler, Pascal Meier, Andre Haeberli, Sidney Shaw, Richard A Smith, Robert Rieben. Attenuation of myocardial reperfusion injury in pigs by Mirococept, a membrane-targeted complement inhibitor derived from human CR1. Cardiovascular Research, 2007; 76(3): 482-93 

Dieter Wallmann, David Tueller, Kerstin Wustmann, Pascal Meier, Joerg Isenegger, Marcel Arnold, Heinrich P Mattle, and Etienne Delacrétaz. Frequent atrial premature beats predict paroxysmal atrial fibrillation in stroke patients: An opportunity for a new diagnostic strategy. Stroke, 2007;38: 2292 

Andreas Indermühle , Rolf Vogel , Pascal Meier, Simone Wirth , Regula Stoop , Markus G Mohaupt , Christian Seiler  The relative myocardial blood volume differentiates between hypertensive heart disease and athlete’s heart in humans. Eur Heart J, 2006; 27 (13): 1571 

Stefano F. De Marchi, Pascal Meier, Philipp Oswald, Christian Seiler. Variable ECG Signs of Ischemia During Controlled Occlusion of the Left and Right Coronary Artery in Humans. Am J Physiol Heart Circ Physiol, 2006; 291: H351 – H356 

Stephan Zbinden, Rainer Zbinden, Pascal Meier, Stephan Windecker, Christian Seiler. Safety and efficacy of subcutaneous-only granulocyte-macrophage colony-stimulating factor for collateral growth promotion in patients with coronary artery disease. J Am Coll Cardiol, 2005;46 (9): 1636-42.

Yara Banz, Otto M Hess, Simon C Robson, Daniel Mettler , Pascal Meier, André Haeberli, Eva Csizmadia, Elena Y Korchagina, Nicolai V Bovin, Robert Rieben. Locally targeted cytoprotection with dextran sulfate attenuates experimental porcine myocardial ischaemia/reperfusion injury. Eur Heart J, 2005;26: 2334-43. 

Rolf Vogel, Andreas Indermühle, Jessica Reinhardt, Pascal Meier, Patrick T Siegrist, Mehdi Namdar, Philipp A Kaufmann, Christian Seiler.  The quantification of absolute myocardial perfusion in humans by contrast echocardiography: algorithm and validation. J Am Coll Cardiol, 2005;45 (5): 754-62.