Dr Stefano Fedele

Dr Stefano FedeleTel: 020 3456 1113
Fax: 020 3456 1005
Email: Eastman.practice@uclh.nhs.uk

Location:
Eastman Dental Hospital

Specialities:
Oral medicine

Professional background

Stefano Fedele completed his degree (DMD, 1993-1998), post-graduate integrated academic/clinical training in Oral Medicine and PhD (1999-2005) at the University Federico II of Naples, Italy.

He moved to University College London/University College London Hospital in 2006 as Clinical Lecturer, and then promoted to Senior Clinical Lecturer (2009) and Honorary Consultant in Oral Medicine in 2012. He’s currently Programme Director of the MSc in Oral Medicine at University College London, Eastman Dental Institute and Head of the Department of Clinical Research at UCL EDI.

He is chair of the Eastman Clinical Investigation Centre, a Clinical Research Facility dedicated to clinical trials and translational research for orofacial disorders. He sits on a number of national and regional advisory boards for clinical research in cancer and oral health including the National Cancer Research institute Clinical Study Group for Head & Neck cancer [NCRI CSG H&N], NCRI Screening, Prevention and Early Diagnosis [SPED] Advisory Group, the NIHR LCRN North Thames (Lead for Oral Health research), the UCLH Research Hub (Lead for Oral Health research).

Dr. Fedele’s clinical expertise includes the following orofacial disorders:

  • Chronic inflammatory disease of the oral mucosa (lichen planus, pemphigus, pemphigoid)
  • Oro-facial granulomatosis (OFG)
  • Oral Cancer and Precancer
  • Jaw bone disease
  • Hyposalivation (dry mouth, xerostomia) and non-neoplastic diseases of the salivary glands

Research interests

Dr. Fedele’s research activity is predominantly focused on clinical and translational research in Oral Medicine. He has published over 90 papers on both general medical and specialist journals including The Lancet, Journal of Clinical Oncology, America Journal of Medicine, Journal of Dental Research, Journal of Oral Pathology & Medicine, and Journal of Rheumatology. Dr Fedele has been awarded as Principal Investigator (or contributed to as Co-Investigator) research grants from several EU and UK funding bodies including FP6, FP7, NIHR Research for Patient Benefit, NIHR Invention for Innovation, Arthritis Research UK for a total of more than £3.000.000. He has been leading multicentre clinical trials in the field of:

  • Novel diagnostics for oral cancer and precancer
  • Novel therapeutics for dry mouth radiotherapy and Sjogren’s syndrome
  • Genetic variants associated with  bisphosphonate-associated osteonecrosis of the jaws
  • Long-term behaviour of bisphosphonate-associated osteonecrosis of the jaws

 

Peer review

Dr Fedele is peer reviewer of more than 20 general medical and specialist Journals. He also regularly reviews grant application for NIHR, Cancer Research UK, and is member of the College of Experts of NIHR HTA.

Publications

Dr Fedele has published over 70 research papers including, review articles, editorials, and original researches on both general medical and specialist journals such as the Lancet, Journal of Clinical Oncology, America Journal of Medicine, Journal of Dental Research, Journal of Oral Pathology & Medicine, and Journal of Rheumatology.

GMC/GDC number: 101700