Mr Manish Chand

Dr Manish ChandTel: 020 3447 5879
Fax: 020 3447 9218

University College London Hospital

Colorectal service, Gastrointestinal services, Endoscopy Unit, General surgery

Professional background

Manish Chand trained as an undergraduate at The Royal Free Hospital and Kings College London obtaining MBBS (Hons) and BSc in Neurosciences (1st Class with Distinction) in 2002. Following a basic surgical rotation through Kings College Hospital, he undertook his higher surgical training in the Wessex region including being Registrar at the prestigious North Hampshire Hospital in Basingstoke. He has been trained in advanced laparoscopic techniques and has an interest in robotic surgery for colorectal cancer. He became a Fellow of The Royal College of Surgeons in 2015.

As part of his sub-specialist development in colorectal surgery he has completed a PhD at Imperial College London. Working with the renowned MERCURY Study Group at The Royal Marsden Hospital, his thesis examined the effect of neoadjuvant chemoradiotherapy on clinical, radiological and molecular aspects of rectal cancer. He remains an active researcher and a recognised academic in rectal cancer with specific interest in imaging and molecular biomarkers. As an academic surgeon, he continues to undertake clinical research and has published more than 75 peer-reviewed articles and book chapters.

In addition to his clinical interests, Mr Chand also holds an MBA degree and has a keen interest in organisational culture and management having completed his dissertation on this subject.

Research interests

  • Rectal cancer; Minimally-invasive surgery and robotics; Molecular and imaging biomarkers; Advanced Endoscopy; Virtual Reality in Surgery; Rectal Cancer
  • Currently one of the Lead Investigators on the NRCN national trial in locally advanced rectal cancer – MARVEL; and joint-PI on the COMET study.
  • Principal Investigator on Laparoscopic versus Robotic colon surgery study
  • Past Chair and Founder of Wessex Research Collaborative.


Which technique to choose in the high-tech era of rectal cancer surgery M Chand, BJ Moran, S Wexner Colorectal Disease 2016; epub ahead of print

Time for a more personlised approach to pre-operative chemoradiation in rectal cancer M Chand, RC Cohen, AC Windsor Chemoradiotherapy: Concurrent Uses, Efficacy and Impact on Prognosis 2016 – in press

Robotic total mesorectaol excision – precision surgery with even more precise tools M Chand, RJ Heald, A Parvaiz Journal of Royal Society of Medicine, 201, 109: 78-79

FDG-PET-CT can assess the response of locally advanced rectal cancer to neoadjuvant chemoradiotherapy: evidence from meta-analysis and systematic review B Rymer, N Curtis, MRS Siddiqui, RI Swift, P Tekkis, M Chand Clinical Nuclear Medicine 2016; 41:371-5

Systematic review of prognostic importance of EMVI in rectal cancer M Chand, MRS Siddiqui, RI Swift, G Brown World Journal of Gastroenterology 2015 (in press)

Obese patients have similar short-term outcomes to the non-obese in laparoscopic colorectal surgery M Chand, H De’Ath, C Mehta, J Bromilow, T Qureshi World Journal of Gastrointestinal Surgery 2015; 7: 261-6

Evidence of radiologic and histopathologic prognostic importance of detecting EMVI in rectal cancer: recommendations for radiology and histopathology reporting M Chand, T Palmer, L Blomqvist, I Naagtegaal, NP West, G Brown Colorectal Disease 2015; 17:468-73

The prognostic significance of post-chemoradiotherapy high-resolution MRI and histopathology detected extramural venous invasion in rectal cancer M Chand, J Evans, RI Swift, P Tekkis, NP West, GWH Stamp, RJ Heald, G Brown Annals of Surgery 2015; 261: 473-9

Total mesorectal excision optimized by pelvic MRI M Chand, Brown G, Tekkis P, Heald RJ Colorectal Dis 2014; 16: 847-53.

A systematic review of emergent laparoscopic colorectal surgery for benign and malignant disease M Chand, M Siddiqui, A Gupta, S Rasheed, P Tekkis, A Parvaiz, AH Mirnezami, T Qureshi World Journal of Gastroenterology 2014 Dec 7;20(45):16956-63

The Clinical Relevance of EMVI in Rectal Cancer M Chand, I Swift, P Tekkis, NP West, RJ Heald, G Brown Colorectal Cancer 2015; 3: 481-90.

Important imaging considerations in the pre-operative assessment of rectal cancer M Chand, G Brown Seminars in Colon and Rectal Surgery 2014; 25: 6-12.

A systematic review and meta-analysis evaluating the role of laparoscopic surgical resection of transverse colon tumours M Chand, M Siddiqui, S Rasheed, P Tekkis, G Brown, A Parvaiz, T Qureshi Surgical Endoscopy 2014; 28(12):3263-72

Evolution in surgical training – What can we learn from professional coaches and elite athletes? M Chand, T Qureshi Journal of Royal Society of Medicine 2014; 107: 290-2.

EMVI-positive stage II rectal cancer has similar clinical outcomes as stage III disease following pre-operative chemoradiotherapy M Chand, A Bhangu, A Wotherspoon, GWH Stamp, RI Swift, P Tekkis, G Brown Annals of Oncology 2014; 25(4):858-63

Adjuvant chemotherapy improves overall survival after TME surgery in mucinous carcinoma of the rectum M Chand, A Bhangu, S Rasheed, RI Swift, GWH Stamp, P Tekkis, G Brown European Journal of Surgical Oncology 2014; 40:240-5.

Extramural venous invasion (EMVI) is a potential imaging predictive biomarker of neoadjuvant treatment in rectal cancer M Chand, I Swift, P Tekkis, I Chau, G Brown British J Cancer 2014; 110: 19-25.

Mucinous carcinoma of the rectum: a distinct clinicopathological entity M Chand, S. Yu, RI. Swift, PP Tekkis, G. Brown Techniques in Coloproctology 2014; 18(4):335-44

Lymph node status does not predict local recurrence in the TME-era M Chand, B Moran, R Glynne-Jones, RJ Heald, G Brown Diseases Colon and Rectum 2014; 57(1):127-9

The importance of not overstaging mesorectal lymph nodes seen on MRI M Chand, RJ Heald, G Brown Colorectal Disease 2013; 15: 1201-1204

Laparoscopic Rectal Cancer Surgery – Clinical Review M Chand, J Bhoday, G Brown, BJ Moran, AC Parvaiz Journal of Royal Society in Medicine 2012; 105:429-35.

Is splenic flexure mobilization necessary in laparoscopic anterior resection? M Chand, D Miksovic, AC Parvaiz Diseases of Colon and Rectum 2012; 55(11):1195-1197.

Bariatric Surgery for the General Surgeon – How to manage post-operative complications K Hamdan, SS Somers, M Chand British Journal of Surgery 2011; 98(10): 1345-55.

Laparoscopic Rectal Cancer Surgery - Editorial M Chand, RJ Heald British Journal of Surgery 2011; 98(2): 166-7

GMC/GDC number: 6056401