Prof Raymond MacAllister

Prof Raymond MacAllisterTel: 020 3447 7139
Fax: 020 3447 9652
Email: r.macallister@ucl.ac.uk

Location:
University College Hospital

Specialities:
General Medicine

Professional background

BA 1984 Gonville and Caius College, Cambridge University  MBBS 1987 Charing Cross and Westminster Medical School, University of London  MRCP 1990  MD 1995 University of London       
 
1996-presemt Professor of Clinical Pharmacology and Honorary Consultant Physician, University College London

Research interests

  • General internal medicine
  • Acute medicine
  • Cardiovascular disease 
  • Medicines policy

Publications

1. Kharbanda R, Peters M, Walton B, Kattenhorn M, Mullen M, Klein N, Vallance P, Deanfield J, MacAllister RJ. Ischemic preconditioning prevents endothelial injury and systemic neutrophil activation during ischemia-reperfusion in humans in vivo. Circulation, 2001 103, 1624-1630   
 
2. Kharbanda RK, Mortensen UM, White PA, Kritianson SB, Schmidt MR, Hoschtitzky JA, Vogel M, Sorensen K, Redington AN and MacAllister RJ. Transient limb ischemia induces remote ischemic preconditioning in vivo. Circulation 2002 106, 2881-2883     
 
3. Broadhead MW, Kharbanda RK, Peters MJ, MacAllister RJ. KATP channel activation induces ischemic preconditioning of the endothelium in humans in vivo. Circulation 2004 110:2077-2082   
 
4. Loukogeorgakis PL, Panagiotidou A, Broadhead MW, Donald A, Deanfield JE, MacAllister RJ. Remote ischemic preconditioning provides early and late protection from endothelial ischemia reperfusion injury in humans; role of the autonomic nervous system. J Am Coll Cardiol 2005 46, 450-456   
 
5. Effects of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes. Systematic review and meta-analysis. Casas JP, Chua.W, Loukogeorgakis S, Vallance P, Smeeth L. Hingorani AD, MacAllister RJ.  Lancet 2005 366, 2026-2023     
 
6. Loukogeorgakis SP, Panagiotidou AT, Yellon DM, Deanfield JE, MacAllister RJ.Postconditioning protects against endothelial ischemia-reperfusion injury in the human forearm.  Circulation 2006; 113:1015-1019.   
 
7. Hausenloy D, Mwamure P, Harris J, Barnard M, Grundy E, Ashley E, Di Salvo C, Vichare S, Kolvekar S, Hayward M, Keogh B, MacAllister R, Yellon D. Remote ischaemic preconditioning protects the heart at time of CABG surgery. Lancet 2007; 370:575-579   
 
8. Mayahi L, Heales S, Owen D, Casas JP, Harris J, MacAllister RJ, Hingorani AD.  (6R)-5,6,7,8-tetrahydro-L-biopterin and its stereoisomer prevent ischemia-reperfusion injury in human forearm. Arterioscler Thromb Vasc Biol. 2007;27:1334-1339.    
 
9. Loukogeorgakis SP, Donald A, Yellon D, Deanfield JE, MacAllister RJ. Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a KATP channel-dependent mechanism. Circulation 2007; 116: 1386-1395   
 
10. Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin N, MacAllister R, Hobbs AJ, Ahluwalia A. Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension 2008; 51: 784-90   
 
11. Loukogeorgakis SP, van den Berg MJ, Sofat R, Nitsch D, Charakida M, Haiyee B, de Groot E, MacAllister RJ, Kuijpers TW, Deanfield JE. Role of NADPH oxidase in endothelial ischemia/reperfusion injury in humans. Circulation. 2010; 121: 2310-6.    
 
12. Kapil V, Milsom AB, Okorie M, Maleki-Toyserkani S, Akram F, Rehman F, Arghandawi S, Pearl V, Benjamin N, Loukogeorgakis S, Macallister R, Hobbs AJ, Webb AJ, Ahluwalia A. Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO. Hypertension. 2010; 56: 274-81.    
 
13. Loukogeorgakis SP, Rees L, Dalton NR, MacAllister RJ, Deanfield JE. Remote ischemic preconditioning protects against ischemia reperfusion injury in pediatric renal transplantation. In press  J Am Soc Nephrol