The Centre for Neuromuscular Diseases draws together the expertise of a large team of specialist clinical neurologists, neurophysiologists, neuropathologists, neurophysiotherapists and specialist nurses in the clinical management of neuromuscular muscle wasting diseases such as motor neuron disease, myasthenia gravis, muscular dystrophy and peripheral neuropathy. In addition there is an active clinical and preclinical research programme into these disorders. As such, it is one of the leading centres for research into neuromuscular diseases in the UK.
We see around 3,500 patients each year in the muscle, peripheral nerve, motor neurone disease and myasthenia clinics. The muscle and peripheral nerve services have both experienced a rapid expansion in recent years, driven by demand for treatment. We are also actively involved in research into the genetic and acquired neuromuscular diseases, are involved in clinical trials of new treatments and offer specialist clinics for genetic neuromuscular diseases.
We have recently been awarded a grant to set up the MRC Centre for Neuromuscular Diseases at UCL and the National Hospital, in conjunction with the University of Newcastle and Great Ormond Street Hospital. The Centre, the first of its kind in the UK, promotes translational research in neuromuscular disease - a bench to bedside approach that is intended to facilitate the rapid transfer of research knowledge to the clinical environment.
- muscle channelopathies
- brain channelopathies
- mitochondrial disease
- dystrophies e.g LGMD, FSHD, myotonic, distal muscle dystrophy, Duchenne's muscular dystrophy, Becker's muscular dystrophy
- Inflammatory muscle diseases e.g polymyositis, dermatomyositis, IBM inflammatory and non inflammatory
- NMJ diseases e.g myasthenia gravis, neuromyotonia, cramp fasciculation syndrome, fibromyalgia
- droped head syndrome
- Peripheral neuropathy