Neurogenetics Laboratory  

The Neurogenetics Unit is situated within the Department of Molecular Neuroscience at the Institute of Neurology. Included in the unit is the Neurogenetics Laboratory of the National Hospital for Neurology and Neurosurgery/University College London Hospital. The Neurogenetics Laboratory is a UKAS accredited medical laboratory No.8040 the scope of our current accreditation is specified on the UKAS website. Users are advised to check this record independently for assurance of the accreditation status of tests requested as some may be newly developed and as yet not accredited. The Neurogenetics Laboratory provides a regional, national and international diagnostic service for inherited neurological disorders.

Our user manual provides contact details for the laboratory, sample requirement specifications, a list of the full current test repertoire, methodology, reporting times and costs.

Our user manual also contains information for users written in collaboration with consultants from NHNN on genetic tests in Parkinsons disease and parkinsonism, Inherited ataxias, Huntingtons disease and choreiform disorders, Dystonias, neuropathies, muscle and ion channel diseases, episodic neurological disorders, dementia and hereditary spastic paraplegia.


Important notice to service users, February 2016:

Due to staff shortages and higher than expected demand, there are backlogs and reporting delays for some tests in the Neurogenetics Laboratory.

The next generation sequencing panel tests (including the brain ion channelopathies, CMT1, CMT2, dHMN, HSN, dementia, muscle ion channelopathies and Parkinson's disease panels) currently have turnaround times of 9-12 months, and the whole mitochondrial genome sequencing service currently has a 6-9 month turnaround time. Referrals marked as clinically urgent are prioritised.

We are working to address these issues as soon as possible.

Please contact the laboratory if you require any further information.


Service performance

The Neurogenetics laboratory provides a local; national and international genetic diagnostic service for inherited neurological disease. Blood and tissue samples are referred to the laboratory on a daily basis. The laboratory now hosts a DNA bank that holds over  65,000 samples, receives over 4000 samples and carries out over 6000 DNA extractions on an annual basis. 

Neurogenetics Laboratory

Prof Sarah Tabrizi Neurogenetics Laboratory
Miss Rachel Taylor Neurogenetics Laboratory , Neurogenetics
Prof Paola Giunti Neurogenetics Laboratory , Neurogenetics
Prof Michael Hanna Neuromuscular disease, Neurogenetics Laboratory , Neurology and neurosurgery
Prof Nicholas Wood Neurogenetics Laboratory , Neurogenetics

 Contact details

General enquiries
Email: ucl-tr.NHNNgenetics@nhs.net / neurogeneticslab@uclh.nhs.uk

Other information

Please note that the contact details given above should not be used for patient enquires. Patients requiring further information regarding the progress of their genetic test or referral should contact their GP or referring clinician.

GP Enquires
Please contact the referring clinician.

Patient Enquires
The laboratory does not provide results direct to patients or GP’s.  For further information please contact your referring clinician.

For urgent clinical advice contact the on-call neurology or neurosurgery SpR. Telephone: 0845 155 5000 or 020 3456 7890

Service manager - Henry Houlden
Email: Henry.Houlden@uclh.nhs.uk

 User manual