Prof Monty Mythen

Prof Michael MythenTel: 020 3447 3343 / 020 3447 3359
Fax: 020 7679 4087

University College Hospital

Critical care, Anaesthesia and Perioperative Medicine, Theatres

Professional background

Prof Michael (Monty) Mythen completed his UK anaesthesia fellowship (FRCA) in 1990, and then went on to gain an MD in 1995 and was appointed assistant professor at Duke University Medical Centre, North Carolina, USA before returning to the UK. He has a wide range of research interests including; peri-operative fluid management and trans-oesophageal Doppler, haemostasis in the critically ill, endotoxin and endotoxin immunity and the determinants of post-operative morbidity and mortality. He is a prolific author and has extensive editorial involvement with a number of anaesthetic and critical care journals. He recently took part in the 'Caudwell Xtreme Everest' project  and as project leader spent three months as the laboratory manager at The Smiths Medical High altitude laboratory, Namche, Nepal (3,500m) - see (See also Grocott M et al.  Arterial blood gases and oxygen content in climbers on Mount Everest. N Engl J Med 2009 Jan 8;360(2):140-9. )  
His present appointments are: 
Smiths Medical Professor of Anaesthesia and Critical Care, UCL and Honorary Consultant Anaesthesia and Critical Care UCL Hospitals NHS Trust 
Director, Centre for Anaesthesia, UCL
Director, Joint UCLH/UCL Biomedical Research Unit. 
Executive Board Member, UCLH/UCL NIHR Comprehensive Biomedical Research Centre
Co-Director, Surgical Outcomes Research Centre, UCLH

Research interests

  • Anaesthesia/critical care
  • Enhanced recovery from surgery
  • Surgical Outcomes Research Centre, UCLH


Five highly cited publications: (of >100 articles on Google Scholar; h-index 28)  
1. M. G. Mythen and A. R. Webb. Intraoperative Gut Mucosal Hypoperfusion Is Associated with Increased Postoperative Complications and Cost. Intensive Care Medicine 20 (2):99-104, 1994. (Cited  203 times). 
2. M. G. Mythen and A. R. Webb. Perioperative Plasma-Volume Expansion Reduces the Incidence of Gut Mucosal Hypoperfusion During Cardiac-Surgery. Archives of Surgery 130 (4):423-429, 1995. (Cited 333 times).     
3. E. BennettGuerrero, L. Ayuso, C. HamiltonDavies, W. D. White, G. R. Barclay, P. K. Smith, S. A. King, L. H. Muhlbaier, M. F. Newman, and M. G. Mythen. Relationship of preoperative antiendotoxin core antibodies and adverse outcomes following cardiac surgery. JAMA 277 (8):646-650, 1997. (Cited 92 times). 
4. T. J. Gan, E. Bennett-Guerrero, B. Phillips-Bute, H. Wakeling, D. M. Moskowitz, Y. Olufolabi, S. N. Konstadt, C. Bradford, P. S. A. Glass, S. J. Machin, and M. G. Mythen. Hextend (R), a physiologically balanced plasma expander for large volume use in major surgery: A randomized phase III clinical trial. Anesthesia and Analgesia 88 (5):992-998, 1999. (Cited 133 times). 
5. N. J. Wilkes, R. Woolf, M. Mutch, S. V. Mallett, T. Peachey, R. Stephens, and M. G. Mythen. The effects of balanced versus saline-based hetastarch and crystalloid solutions on acid-base and electrolyte status and gastric mucosal perfusion in elderly surgical patients. Anesthesia and Analgesia 93 (4):811-816, 2001.(Cited 130 times).

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