Dr Jessica Manson

Dr Jessica MansonTel: 020 34467 9035
Fax: 020 3447 9278
Email: uclh.rheumatology@nhs.net

University College Hospital


Professional background

Dr Jessica Manson is a consultant rheumatologist. Her clinical interests include acute rheumatology, inflammatory arthritis and chronic pain.

She was awarded Clinical Research Fellowship from Arthritis Research UK, and subsequently a PhD from UCL for her research into kidney disease in systemic lupus erythematosus.

She has an honorary senior lectureship at UCL, where she is currently principal investigator for two studies investigating the causes and treatment of rheumatoid arthritis.

She is regularly involved in teaching medical students, junior doctors and allied health professionals.

Research interests

Rheumatoid arthritis - with on-going grant funding in three main areas:

  • Patients with active disease but normal serum inflammatory markers
  • The develpoment of anti-drug antibodies
  • The role of the microbiome


Mouyis M, Fitz-Clarence H, Manson J, Ciurtin C. Teriparatide: an unexpected adjunct for the treatment of a long-standing infected elbow prosthesis prevented arm amputation. Clinical Rheumatology 2015; 34 (4) 799-800

Ciurtin C, Shirodaria A, Manson J, MacMillan R. Polyarteritis nodosa associated with necrosis of the tongue: a rare presentation in an adult patient British Journal of Oral and Maxillofacial Surgery 2015: 53 (9) p883–885

Raithatha N, Mehrtens S, Mouyis M, Manson J. Rash and fever after sulphasalazine. BMJ 2014; 349

Manson JJ, Mills K, Jury E, Mason L, D’Cruz D, Ni L, Saleem M, Mathieson P, Isenberg D, Rahman A. Pathogenic autoantibodies from patients with lupus nephritis cause reduced tyrosine phosphorylation of podocyte proteins, including tubulin. Lupus Science and Medicine. 2014: 1.

Parker S, Gil E, Ward K, Reyal Y, Wilson S, Hewitt P , Manson JJ. Passive transfer of hepatitis B antibodies from intravenous immunoglobulin. BMC Infectious Diseases. 2014: 14:99

Mahil S, McGregor A, Manson JJ. Exercise induced pyomyositis. BMJ. 2012; 345.

Manson JJ, Ma A, Rogers P, Mason LJ, Berden JH, Van der Vlag J, D’Cruz D, Isenberg DA, Rahman A. Relationship between anti-dsDNA, anti-nucleosome and anti-alpha-actinin antibodies and markers of renal disease in a longitudinal study of patients with new onset lupus nephritis. Arthritis Res Ther. 2009; 11(5)R154.

Lambrianides A, Giles I, Ioannou Y, Mason L, Manson J, Latchman DS, Isenberg DA and Rahman A. Arginine mutation alters binding of a human monoclonal antibody to antigens linked to systemic lupus erythematosus and the antiphospholipid antibody syndrome. Arthritis Rheum 2007; 56(7):2392-401.

Ng KP, Manson JJ, Rahman A, Isenberg DA. Association of anti-nucleosome antibodies with disease flare in serologically active clinically quiescent patients with systemic lupus erythematosus. Arthritis Rheum 2006; 55(6): 900-4.

Cambridge G, Leandro MJ, Teodorescu M, Manson J, Rahman A, Isenberg DA, Edwards JC. B Cell Depletion Therapy in Systemic Lupus Erythematosus: Effect on autoantibody and anti-microbial antibody Profiles. Arthritis Rheum 2006; 54(11): 3612-22.

Mason LJ, Lambrianides A, Haley JD, Manson JJ, Latchman DS, Isenberg DA, Rahman A. Stable expression of a recombinant human anti-nucleosome antibody to investigate relationships between antibody sequence, binding properties and pathogenicity. Arthritis Res Ther 2005; 7(5): R971-83.

Manson JJ, Mauri C, Ehrenstein M. Natural serum IgM maintains immunological homeostasis and prevents autoimmunity. Springer Semin Immunopathol 2005; 4: 425-432.

GMC/GDC number: 4536460 

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