Prof Steve Pereira

Dr Steve PereiraTel: 020 3447 9229
Fax: 020 3447 9218

University College Hospital

Hepato Pancreato Bilary Cancers HPB, Endoscopy Unit, Pancreatobiliary service, Gastrointestinal services

Professional background

Steve Pereira studied science and medicine at University of New South Wales, Sydney, with postgraduate training in gastroenterology and hepatology mainly at Guy’s and King’s College hospitals, London and advanced endoscopy training in Paris, Amsterdam and Indianapolis. He has been a consultant at University College Hospital since 2000, and is also a Reader in Hepatology and Gastroenterology at University College London and an honorary consultant at the Royal Free Hospital.

His clinical and research interests centre on the causes, early diagnosis and treatment of liver and pancreatic cancer, as well as benign biliary and pancreatic diseases. These conditions represent a significant number of patients referred for specialist opinion to UCLH, and the activity of the research group is linked closely with the clinical hepatopancreaticobiliary service at UCLH and the Royal Free. He is currently Chairman of the British Society of Gastroenterology Pancreatic Section,  previous Chairman of the North-East Thames Gastroenterology Training Committee and past President of the Pancreatic Society of GB&I. He also serves on the European Society of Gastrointestinal Endoscopy Education Committee and the British Society of Gastroenterology Council.

Research interests

  • Serum biomarkers of pancreaticobiliary malignancy
  • Optical diagnostics and treatment monitoring
  • Cystic tumours of the pancreas
  • Photodynamic therapy
  • Primary sclerosing cholangitis
  • Immunology of hepatocellular and pancreatic cancer
  • Serum and bile proteomics in pancreaticobiliary malignancy
  • Inhibitors of DNA replication in pancreatic cancer
  • Symptom identification in pancreatic malignancy
  • Sphincter of Oddi dysfunction
  • Complications of chronic pancreatitis


  • Huang HC, Rizvi I, Liu J, Anbil S, Kalra A, Lee H, Baglo Y, Paz N, Hayden D, Pereira SP, Pogue BW, Fitzgerald J, Hasan T. Photodynamic priming mitigates chemotherapeutic selection pressures and improves drug delivery. Cancer Res 2018; 78: 558-71.
  • Venkatachalapathy SV, Bekkali N, Pereira SP, Johnson GJ, Paranandi B, Oppong KW, Nayar MK, Leeds J, Penman I, Carroll NR, Godfrey EM, James M, Aithal G, McKay CJ, Devlin J, Wong T, Makin A, Ryan BM, Huggett MT. Multicentre experience from the UK and Ireland of the use of lumen apposing metal stents (LAMS) for trans-drainage of pancreatic fluid collections. Endosc Internat Open 2018; 6: E259-65.
  • Keane MG, Kumar M, Cieplik N, Thorburn D, Johnson GJ, Webster GJ, Chapman M, Lindley KJ, Pereira SP. Paediatric advanced endoscopy: a 21-year experience from a tertiary hepatobiliary centre and systematic literature review. BMC Paed 2018; 18: 42. doi: 10.1186/s12887-017-0959-9.
  • Ghaneh P, Hanson R, Titman A, Lancaster G, Plumpton C, Lloyd-Williams H, Yeo ST, Edwards RT, Johnson C, Abu Hilal M, Higginson AP, Armstrong T, Smith A, Scarsbrook A, McKay C, Carter R, Sutcliffe RP, Bramhall S, Kocher HM, Cunningham D, Pereira SP, Davidson B, Chang D, Khan S, Zealley I, Sarker D, Al Sarireh B, Charnley R, Lobo D, Nicolson M, Halloran C, Raraty M, Sutton R, Vinjamuri S, Evans J, Campbell F, Deeks J, Sanghera B, Wong WL, Neoptolemos JP. PET-PANC: multicentre prospective diagnostic accuracy and health economic analysis study of the impact of combined modality 18fluorine-2-fluoro-2-deoxy-d-glucose positron emission tomography with computed tomography scanning in the diagnosis and management of pancreatic cancer. Health Technol Assess 2018; 22 :1-114. doi: 10.3310/hta22070.
  • Uribarri-Gonzalez L, Keane G, Lariño-Noia J, Pereira SP, Iglesias-Garcia J, Enrique Dominguez-Muñoz J. Agreement among magnetic resonance imaging / magnetic resonance cholangiopancreatography (MRI-MRCP) and endoscopic ultrasound (EUS) in the evaluation of morphological features of branch duct intraductal papillary mucinous neoplasm (BD-IPMN). Pancreatology 2018; 18: 170-75.
  • Keane MG, Shamali A, Nilsson LN, Antila A, Bocos JM, Van Zanten MM, Gil CV, Maisonneuve P, Vaalavuo Y, Hoskins T, Robinson S, Ceyha G, Hilal MA, Pereira SP, Laukkarinen J, Del Chiaro M. Risk of malignancy in resected pancreatic mucinous cystic neoplasms. Br J Surg 2018; 105: 493-46.
  • Hirschfield GM, Dyson JK, Alexander GJM, Chapman MH, Collier J, Hübscher S, Patanwala I, Pereira SP, Thain C, Thorburn D, Tiniakos D, Walmsley M, Webster G, Jones DEJ. The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines. Gut2018 Mar 28 [Epub ahead of print].
  • Cuenco J, Wehnert W, Kazarian A, Whitwell HJ, Blyuss O, Menon U, Dawnay A, Manns MP, Pereira SP, Timms JF. Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholangitis. Oncotarget 2018; 9: 17430-17442.
  • Aabakken L, Karlsen TH, Albert T, Arvanitakis M, Chazouilleres O, Dumonceau JM, Färkkilä M, Fickert P, Hirschfield G, Laghi A, Marzioni M, Michael F, Pereira SP, Pohl J, Poley JW, Ponsioen CI, Schramm C, Swahn F, Tringali A, Hassan C. Role of endoscopy in primary sclerosing cholangitis:  ESGE/EASL clinical guidelines. J Hepatol 2017; 66: 1265-81.
  • Keane MG, Keane MG, Huggett MT, Chapman MH, Johnson GJ, Webster GJ, Thorburn D, Mackay J, Pereira SP. Diagnosis of pancreaticobiliary malignancy by detection of minichromosome maintenance protein 5 in biliary brush cytology. Br J Ca 2017; 116: 349-55.

GMC/GDC number: 3515969