Dr Neil Stone

Email: neil.stone@nhs.net

Location:
University College Hospital, Hospital for Tropical Diseases

Specialities:
Tropical and infectious diseases, Microbiology

Professional background

Qualified in Medicine from Guy's, King's College and St. Thomas' Medical School in 2004
Specialist Training in Infectious Diseases and Microbiology in London
Clinical experience in Zambia, Tanzania, Uganda, Malawi and Nigeria
Completed a PhD on Cryptococcal Meningitis at St. George's, University of London
Honorary Assistant Professor at the London School of Hygiene and Tropical Medicine
Special interest in invasive fungal disease and new diagnostics and treatments for fungal disease

Research interests

Diagnosis and treatment of Invasive Fungal Disease
Cryptococcal Meningitis
Antifungal drug resistance
Fungal Infections in the Immmunosuppressed

Publications

  • MAZZELLA, A.; STONE, N. R. H.; POOL, E. R. M.; GARCÍA MINGO, A. et al. HIV-associated disseminated histoplasmosis successfully treated with isavuconazole consolidation therapy. Med Mycol Case Rep, 27, p. 42-43, Mar 2020
  • HOPE, W.; STONE, N. R. H.; JOHNSON, A.; MCENTEE, L. et al. Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of Cryptococcal Meningitis Because of Emergence of Resistance. mBio, 10, n. 6, 12 2019
  • STONE, N. R.; RHODES, J.; FISHER, M. C.; MFINANGA, S. et al. Dynamic ploidy changes drive fluconazole resistance in human cryptococcal meningitis. J Clin Invest, Jan 2019.
  • MOLLOY, S. F.; BRADLEY, J.; KARUNAHARAN, N.; MPUTU, M. et al. Effect of oral fluconazole 1200 mg/day on QT interval in African adults with HIV-associated cryptococcal meningitis. AIDS, 32, n. 15, p. 2259-2261, Sep 2018
  • MOLLOY, S. F.; KANYAMA, C.; HEYDERMAN, R. S.; LOYSE, A. et al. Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa. N Engl J Med, 378, n. 11, p. 1004-1017, 03 2018.
  • STONE, N. R.; BICANIC, T.; SALIM, R.; HOPE, W. Liposomal Amphotericin B (AmBisome(®)): A Review of the Pharmacokinetics, Pharmacodynamics, Clinical Experience and Future Directions. Drugs, 76, n. 4, p. 485-500, Mar 2016.
  • WERTHEIMER, N. B.; STONE, N.; BERMAN, J. Ploidy dynamics and evolvability in fungi. Phil. Trans. R. Soc. B, 371, n. 1709, p. 20150461, 2016.
  • MAY, R. C.; STONE, N. R.; WIESNER, D. L.; BICANIC, T. et al. Cryptococcus: from environmental saprophyte to global pathogen. Nat Rev Microbiol, Dec 2015.
  • DOUGLAS-VAIL, M.; BECHAMP, T.; GOHAL, S.; SOEGTROP, R. et al. Reversible deafness and blindness in a patient with cryptococcal meningitis in Tanzania. Infectious Disease Reports, 7, n. 4, 2015.
  • STONE, N. R.; MARTIN, T.; BISWAS, J.; BARRETT, J. et al. Bacteroides-Associated Pylephlebitis in a Patient with Strongyloidiasis. Am J Trop Med Hyg, Dec 2014.
  • BUSTINDUY, A. L.; LUZINDA, K.; MPOYA, S.; GOTHARD, P. et al. Endomyocardial Fibrosis (EMF) in a Ugandan Child with Advanced Hepatosplenic Schistosomiasis: Coincidence or Connection? Am J Trop Med Hyg, Jul 2014.
  • GORTON, R. L.; RAMNARAIN, P.; BARKER, K.; STONE, N. et al. Comparative analysis of Gram's stain, PNA-FISH and Sepsityper with MALDI-TOF MS for the identification of yeast direct from positive blood cultures. Mycoses, 57, n. 10, p. 592-601, Oct 2014.
  • STONE, N. R.; GORTON, R. L.; BARKER, K.; RAMNARAIN, P. et al. Evaluation of PNA-FISH yeast traffic light for rapid identification of yeast directly from positive blood cultures and assessment of clinical impact. J Clin Microbiol, 51, n. 4, p. 1301-1302, Apr 2013.
  • STONE, N. R.; WOODFORD, N.; LIVERMORE, D. M.; HOWARD, J. et al. Breakthrough bacteraemia due to tigecycline-resistant Escherichia coli with New Delhi metallo-β-lactamase (NDM)-1 successfully treated with colistin in a patient with calciphylaxis. J Antimicrob Chemother, 66, n. 11, p. 2677-2678, Nov 2011.
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GMC/GDC number: 6104344