Head and neck sarcomas are a group of tumours that require particularly careful management for the best results. Both soft tissue and bone tumours can arise, of a wide range of types, frequently needing complex combination treatments. This requires close working of sarcoma oncologists with head and neck surgeons. The sarcoma oncologists sub-specialising in head and neck sarcomas regularly attend the weekly head and neck MDT Meeting to discuss the large number of head and neck sarcomas treated.

Surgeons

KalavrezosNicholas.jpgI am a Head and Neck Reconstructive Surgeon and the Lead Clinician in the Head and Neck Centre at University College London Hospital with a background in Oral and Maxillo-Facial surgery.  I am also the Lead Head and Neck Sarcoma Surgeon for the London Sarcoma Service. My clinical practice includes major surgery for the head and neck with a special interest in bone sarcomas.

My research interests include applications of “tissue engineering”. I am a founding member of the “Centre for Reconstructive Surgery” at University College London. I hold a Senior Lecturer post at the same Institution. I have joint research projects in the Nanotechnology Lab of UCL on “tissue engineered bio-scaffolding” aiming to replace defects of the head and neck with tissue–engineered based micro-vascular flap reconstruction.

I give lectures regularly nationally and internationally and hold the position of the Secretary General of the European Association for Cranio-Maxillofacial Surgery (EACMFS).

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VazFrancis.jpgI have a busy Head and Neck practice where I see both benign and malignant pathology.

I run a diagnostic neck lump clinic and also see a large amount of voice pathology within this clinic.

I undertake parotid, submandibular and thyroid gland surgery as this compliments my Head and Neck practice well.

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Oncologists

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I completed my clinical training at St Bartholomew’s and University College London Hospitals. I completed a PhD at the Institute of Cancer Research and the Royal Marsden Hospital which looked at the genes that predispose patients to prostate cancer.

I now specialise in the treatment of soft tissue and bone sarcomas using chemotherapy and radiotherapy. I have a strong interest in clinical research and am currently in the process of developing a number of new local and national research projects in sarcoma. I teach and lecture regularly in the management of sarcomas.

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Franel Le Grange resize2.jpgI trained as a Clinical Oncologist in South Africa and was awarded a CESR in Clinical Oncology by the Royal College of Radiologist. I have worked with the London Sarcoma Service at University College Hospital since 2009 and now specialise exclusively in the treatment of sarcomas.

I developed an interest in sarcoma during my training and now specialise in the management of bone and soft tissue sarcomas as well as fibromatosis. I have a special interest in developing the use of advanced radiotherapy techniques for the treatment of sarcomas and to that end I am involved in research funded by the Bone Cancer Research Trust and Cancer Research UK. I have an interest in education and I am involved in teaching both medical students and specialty trainees.

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I was educated and started my training in Internal Medicine in Greece. I also conducted my PhD at University of Ioannina in angiogenesis and proteolysis in cancer of unknown primary site. I completed my specialist training in Oncology at the Royal Marsden Hospital in London during a 3 years fellowship. I followed an academical career in Aristotle University of Thessaloniki in Greece and I led the Medical Oncology Department during my last year of my stay there. In 2015 I was appointed as a Consultant Medical Oncologist at UCLH and I am exclusively treating patients with bone and soft tissue sarcomas with systemic treatment within the London Sarcoma Service.

I have a strong interest in clinical trials across multiple tumor types and more recently in sarcoma, acting as principal and co-investigator for a number of national and international trials. Since my early days in my career, I was involved in the conduction of early clinical trials both in UK and Greece with novel agents and I have experience in pharmacokinetics and pharmacodynamic models. 

I have published more than 100 publications in per reviewed journals in clinical and translational research and I regularly teach and lecture in the management of sarcomas. I also hold an honorary clinical senior lectureship contract with UCL and I contribute to the teaching of the medical students. I am member of several scientific organizations including British sarcoma Group, EORTC Soft Tissue and Bone Sarcoma Group, ESMO, ASCO, HeSMO etc.

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Histopathologists

I am a FA resize.jpgConsultant Histopathologist with a special interest in bone and soft tissue tumour: diagnostic aspects and molecular genetics. I have worked in a large tertiary hospital in Sao Paulo, Brazil as a consultant for 12 years before taking the current post at the Royal National Orthopaedic Hospital (RNOH) in 2010. I completed my Ph.D. in 2007 with focus in molecular genetics of sarcomas, and since them my research interest includes molecular aspects in the diagnosis and treatment of sarcomas. I am the clinical lead for Molecular Pathology at the histopathology department at RNOH and Honorary Senior Lecturer at University College London, Cancer Institute.

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Adrienne.jpgI am the clinical lead for the diagnostic pathology service for the London Sarcoma Service undertaking the NHS service work at the Royal National Orthopaedic Hospital NHS Trust. My research is based in the NHS Histopathology Department in Stanmore, and in the Paul O'Gorman Cancer Institute, Huntley Street, UCL.

Making a correct diagnosis is pivotal in deciding the best treatment for a patient. Cancer is caused by genetic alterations in cells and we can use these genetic changes to diagnose tumours accurately. Over the last 10 years, my research has focused on improving the way that we provide diagnoses for patients. In collaboration with my NHS colleagues we have translated this research into clinical practice and are using our findings every day in clinical practice.

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IRP_2_417a GF resize.jpgI am a full-time Consultant Histopathologist with exclusive interest in the biology and pathology of bone and soft tissue tumours.

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Radiologists

profile ID.pngI am a consultant radiologist (imaging doctor), specialising in imaging of the head and neck. My job involves interpreting MRI and CT scans of patients with sarcoma to determine how extensive the disease is to help the surgeons, oncologists and other professionals in the unit decide on the type of treatment to administer. I regularly perform ultrasound scans on patients with sarcoma, which helps to map disease. I also use ultrasound as a guide to performing biopsies that may be required in patients with sarcomas of the head and neck.

My training in radiology began at St. George's Hospital in London and I completed my radiology training at UCLH and the Royal National ENT and Eastman Dental Hospitals, also in London, after which I was appointed as a consultant.

I am heavily involved in training and education of junior radiologists and other doctors and I am the departmental clinical lead for MRI, facilitating the delivery of a safe and high quality MRI service for all patients across the hospital.