Histiocytic Disorders : University College London Hospitals NHS Foundation Trust

Histiocytic disorders are a range of rare non-cancerous conditions. They are also called histiocytic neoplasms. They affect a type of immune cell called histiocytes. Histiocytes live in your body’s tissues and help protect you from infections while keeping your tissues healthy.

Some histiocytes can change and become cancerous. When this happens, too many abnormal histiocytes build up in your organs.

Histiocytic neoplasms may affect one area or several parts of the body. Common places they affect include the bones, lymph nodes, liver, spleen and skin.

At UCLH, we have a specialist clinic dedicated to caring for people affected by histiocytic disorders. We also work closely with the national histiocytosis advisory panel.

Dr Gohil and Dr McNamara, who both run the adult histiocytic disorder clinic at UCLH, are key members of the panel. Dr Sneha Tandon runs a specialist clinic at UCLH for teenagers and young adults who have histiocytic disorders.

Langerhans Cell Histiocytosis
Erdheim Chester Disease
Rosai Dorfman Disease
Langerhans Cell Sarcoma
Histiocytic Sarcoma
ALK+ Histiocytosis

You will also get support from a clinical nurse specialist. They’ll guide you through your diagnosis, treatment and follow-up care. You’ll get their contact details once you’re diagnosed. You can contact them between your hospital appointments if you have any questions or concerns.

The UCLH Macmillan Support and Information Service offers help and advice for people affected by cancer. They provide practical advice, emotional support and information. Visit their web page to find out more.