Dr Emma Drasar

Clinical management of sickle cell liver disease in children and young adults.Kyrana E, Rees D, Lacaille F, Fitzpatrick E, Davenport M, Heaton N, Height S, Samyn M, Mavilio F, Brousse V, Suddle A, Chakravorty S, Verma A, Gupte G, Velangi M, Inusa B, Drasar E, Hadzic N, Grammatikopoulos T, Hind J, Deheragoda M, Sellars M, Dhawan A. Arch Dis Child. 2020 Nov 11 PMID: 33177052

Real-time national survey of COVID-19 in hemoglobinopathy and rare inherited anemia patients.Telfer P, De la Fuente J, Sohal M, Brown R, Eleftheriou P, Roy N, Piel FB, Chakravorty S, Gardner K, Velangi M, Drasar E, Shah F, Porter JB, Trompeter S, Atoyebi W, Szydlo R, Anie KA, Ryan K, Sharif J, Wright J, Astwood E, Nicolle CS, Webster A, Roberts DJ, Lugthart S, Kaya B, Awogbade M, Rees DC, Hollingsworth R, Inusa B, Howard J, Layton DM. Haematologica. 2020 Sep 10;PMID: 33054122 Free PMC article.

Protecting vulnerable patients with inherited anaemias from unnecessary death during the COVID-19 pandemic. Roy NBA, Telfer P, Eleftheriou P, de la Fuente J, Drasar E, Shah F, Roberts D, Atoyebi W, Trompeter S, Layton DM, Lugthart S, Stuart-Smith S, Chakravorty S, Wright J, Porter J, Inusa B, Howard J; National Haemoglobinopathy Panel. Br J Haematol. 2020 May PMID: 32330288

Serial prophylactic exchange blood transfusion in pregnant women with sickle cell disease (TAPS-2): study protocol for a randomised controlled feasibility trial. Oakley LL, Awogbade M, Brien S, Briley A, Chorozoglou M, Drasar E, James J, Rhodes E, Robinson V, Seed P, Sharif J, Singh C, Telfer P, Thompson H, Watt-Coote I, Howard J, Oteng-Ntim E. Trials. 2020 Apr 20;PMID: 32312326

A Phase 3 Trial of Luspatercept in Patients with Transfusion-Dependent β-Thalassemia.Cappellini MD, Viprakasit V, Taher AT, Georgiev P, Kuo KHM, Coates T, Voskaridou E, Liew HK, Pazgal-Kobrowski I, Forni GL, Perrotta S, Khelif A, Lal A, Kattamis A, Vlachaki E, Origa R, Aydinok Y, Bejaoui M, Ho PJ, Chew LP, Bee PC, Lim SM, Lu MY, Tantiworawit A, Ganeva P, Gercheva L, Shah F, Neufeld EJ, Thompson A, Laadem A, Shetty JK, Zou J, Zhang J, Miteva D, Zinger T, Linde PG, Sherman ML, Hermine O, Porter J, Piga A; BELIEVE Investigators. N Engl J Med. 2020 PMID: 32212518

Interim assessment of liver damage in patients with sickle cell disease using new non-invasive techniques.Drašar E,  Fitzpatrick E, Gardner K, Awogbade M, Dhawan A, Bomford A, Suddle A,  Thein SL  Br J Haematol 2017  PMID: 27984631

Survival in adults with sickle cell disease in a high-income setting.Gardner K, Douiri A, Drasar E, Allman M, Mwirigi A, Awogbade M, Thein SL. Blood. 2016 PMID: 27439910

Tissue Iron Distribution Assessed by MRI in Patients with Iron Loading Anemias.Gutiérrez L, House MJ, Vasavda N, Drašar E, Gonzalez-Gascon Y Marin I, Kulasekararaj AG, St Pierre TG, Thein SL.  PLoS One. 2015 PMID: 26406992

Pulmonary Haemodynamics in Sickle Cell Disease Are Driven Predominantly     by a High-Output State Rather Than Elevated Pulmonary Vascular Resistance: A Prospective 3-Dimensional Echocardiography/Doppler Study.

Mushemi-Blake S, Melikian N, Drasar E, Bhan A, Lunt A, Desai SR, Greenough A, Monaghan MJ, Thein SL, Shah AM PLoS One 2015 PMID: 26270484

The clinical significance of K-Cl cotransport activity in red cells of patients with HbSC disease. Rees DC, Thein SL, Osei A, Drasar E, Tewari S, Hannemann A, Gibson JS. Hematologica. 2015 PMID: 25749827

Spectral domain optical coherence tomography in patients with sickle cell disease.Mathew R, Bafiq R, Ramu J, Pearce E, Richardson M, Drasar E, Thein SL, Sivaprasad S.Br J Ophthalmol. 2015 PMID: 25595176

Global Genetic Architecture of an Erythroid Quantitative Trait Locus, HMIP-2.Menzel S, Rooks H, Zelenika D, Mtatiro SN, Gnanakulasekaran A, Drasar E, Cox S, Liu L, Masood M, Silver N, Garner C, Vasavda N, Howard J, Makani J, Adekile A, Pace B, Spector T, Farrall M, Lathrop M, Thein SL.  Ann Hum Genet. 2014 PMID: 25069958

Leukocyte Telomere Length in Patients with Sickle Cell DiseaseDrasar E, Jiang J, Gardner K, Howard J, Vulliamy T, Vasavda N, Thein SL Br J Haematol. 2014 PMID: 24666270

The Effect of Duffy Antigen Receptor for Chemokines (DARC) on Severity in Sickle Cell Disease Drasar E, Menzel S, Fulford T, and Thein SL Hematologica 2013 PMID: 23753024

Genetic determinants of haemolysis in sickle cell anaemia.Milton JN, Rooks H, Drasar E, McCabe EL, Baldwin CT, Melista E, Gordeuk    VR, Nouraie M, Kato GR, Minniti C, Taylor J, Campbell A, Luchtman-Jones L, Rana S, Castro O, Zhang Y, Thein SL, Sebastiani P, Gladwin MT; Walk- PHAAST Investigators, Steinberg MH. Br J Haematol. 2013 PMID: 23406172

Renal iron load in sickle cell disease is influenced by severity of haemolysis.Vasavda N, Gutiérrez L, House MJ, Drašar E, St Pierre TG, Thein SL.Br J Haematol. 2012 PMID: 22409346

Serum ferritin and total units transfused for assessing iron overload in adults with sickle cell disease.Drasar E, Vasavda N, Igbineweka N, Awogbade M, Allman M, Thein SL.Br J Haematol. 2012 PMID: 22332939

Effects of co-existing α-thalassaemia in sickle cell disease on hydroxycarbamide therapy and circulating nucleic acids.

Vasavda N, Woodley C, Allman M, Drašar E, Awogbade M, Howard J, Thein SL.Br J Haematol. 2012 PMID: 22082280

Association between haemolysis and microalbuminuria in adults with sickle cell anaemia.Day, T*, Drasar E*, Sharpe, C and Thein SL.  Hematologica. 2012 PMID: 21993677 * Joint first authors

Changing pattern of hospital admissions of children with sickle cell disease over the last 50 years. Day TG, Thein SL, Drasar E, Dick MC, Height SE, O'Driscoll S, Rees DC.J Pediatr Hematol Oncol. 2012 PMID: 21941140

Blood transfusion among adults with sickle cell disease – a single institution experience over ten years Drasar E, Igbineweka N, Vasavda N, Free M, et al. Br J Haematol 2011.  PMID: 21275951

Genetics of fetal hemoglobin in Tanzanian and British patients with sickle cell anemia. Makani J, Menzel S, Nkya S, Cox SE, Drasar E, Soka D, et al. Blood 2010. PMID: 21068433