Professional background

Dr Davagnanam was fellowship trained on the Pan-London Neuroradiology fellowship between 2006-2008. He has been a consultant neuroradiologist at the National Hospital for Neurology & Neurosurgery and Moorfields Eye Hospital since 2008.

His clinical expertise involves providing opinions in diagnostic imaging and performing specialist diagnostic procedures for neurological, neuro-vascular, spinal neuro-ophthalmological and orbital conditions. He has a particular interest in stroke, CSF disorders, headache, disease of the spine and ophthalmic disorders.

He has written chapters on his areas of specialist interest in five medical reference textbooks and contributed to Royal College guidelines. He is a council member of the Clinical Neurosciences Section of the Royal Society of Medicine, as well as a member of the British Society of Neuroradiologists, Royal College of Radiologists, International Society for Magnetic Resonance Imaging in Medicine and UK Neuro-Ophthalmology Specialist Interest Group.

He has published over 70 articles in scientific peer-reviewed journals, including original articles in high impact clinical neurosciences journals, and has been invited nationally and internationally to lecture on specialised areas of neuroimaging.

He is a committee member, lecturer and examiner on the Advanced Neuroimaging MSc Programme at the Institute of Neurology, University College London.

Research interests

As an honorary senior lecturer with the UCL Institute of Neurology, he currently leads on research projects with an emphasis on the development and application of quantitative advanced and novel imaging techniques to develop disease specific biomarkers.


  • Chelban V, Patel N, Vandrovcova J, Zanetti MN, Lynch DS, Ryten M, Botía JA, Bello O, Tribollet E, Efthymiou S, Davagnanam I; SYNAPSE Study Group, Bashiri FA, Wood NW, Rothman JE, Alkuraya FS, Houlden H. Mutations in NKX6-2 Cause Progressive Spastic Ataxia and Hypomyelination. Am J Hum Genet. 2017 Jun 1;100(6):969-977. Davendralingam N, Kanagaratnam M, Davagnanam I. 'A crisis in caring': a place for compassionate care in today's medicine. J R Soc Med. 2017 Jun;110(6):225-226.
  • Lynch DS, Rodrigues Brandão de Paiva A, Zhang WJ, Bugiardini E, Freua F, Tavares Lucato L, Macedo-Souza LI, Lakshmanan R, Kinsella JA, Merwick A, Rossor AM, Bajaj N, Herron B, McMonagle P, Morrison PJ, Hughes D, Pittman A, Laurà M, Reilly MM, Warren JD, Mummery CJ, Schott JM, Adams M, Fox NC, Murphy E, Davagnanam I, Kok F, Chataway J, Houlden H. Clinical and genetic characterization of leukoencephalopathies in adults. Brain. 2017 Mar 2.
  • Lakshmanan R, Adams ME, Lynch DS, Kinsella JA, Phadke R, Schott JM, Murphy E, Rohrer JD, Chataway J, Houlden H, Fox NC, Davagnanam I. Redefining the phenotype of ALSP and AARS2 mutation-related leukodystrophy. Neurol Genet. 2017 Feb 15;3(2):e135.
  • Godi C, De Vita E, Tombetti E, Davagnanam I, Haddow L, Jäger HR. High b-value diffusion-weighted imaging in progressive multifocal leukoencephalopathy in HIV patients. Eur Radiol. 2017 Sep;27(9):3593-3599.
  • Lynch DS, Zhang WJ, Lakshmanan R, Kinsella JA, Uzun GA, Karbay M, Tüfekçioglu Z, Hanagasi H, Burke G, Foulds N, Hammans SR, Bhattacharjee A, Wilson H, Adams M, Walker M, Nicoll JA, Chataway J, Fox N, Davagnanam I, Phadke R, Houlden H. Analysis of Mutations in AARS2 in a Series of CSF1R-Negative Patients With Adult-Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia. JAMA Neurol. 2016 Dec 1;73(12):1433-1439.
  • Barritt A, Miller S, Davagnanam I, Matharu M. Rapid diagnosis vital in thunderclap headache. Practitioner. 2016 Apr;260(1792):23-8, 3.
  • Hull S, Arno G, Ku CA, Ge Z, Waseem N, Chandra A, Webster AR, Robson AG, Michaelides M, Weleber RG, Davagnanam I, Chen R, Holder GE, Pennesi ME, Moore AT. Molecular and Clinical Findings in Patients With Knobloch Syndrome. JAMA Ophthalmol. 2016 Jul 1;134(7):753-62.
  • Nikoubashman O, Di Rocco F, Davagnanam I, Mankad K, Zerah M, Wiesmann M. Prospective Hemorrhage Rates of Cerebral Cavernous Malformations in Children and Adolescents Based on MRI Appearance. AJNR Am J Neuroradiol. 2015 Nov;36(11):2177-83.
  • Tan LT, Davagnanam I, Isa H, Rose GE, Verity DH, Pusey CD, Lightman S. Clinical and Imaging Features of Lacrimal Gland Involvement in Granulomatosis with Polyangiitis. Ophthalmology. 2015 Oct;122(10):2125-9.
  • Pitceathly RD, Morrow JM, Sinclair CD, Woodward C, Sweeney MG, Rahman S, Plant GT, Ali N, Bremner F, Davagnanam I, Yousry TA, Hanna MG, Thornton JS. Extra-ocular muscle MRI in genetically-defined mitochondrial disease. Eur Radiol. 2016 Jan;26(1):130-7.
  • Adams A, Roche O, Mazumder A, Davagnanam I, Mankad K. Imaging of degenerative lumbar intervertebral discs; linking anatomy, pathology and imaging. Postgrad Med J. 2014 Sep;90(1067):511-9.
  • Chandra A, Arno G, Williamson K, Sergouniotis PI, Preising MN, Charteris DG, Thompson DA, Holder GE, Borman AD, Davagnanam I, Webster AR, Lorenz B, FitzPatrick DR, Moore AT. Expansion of ocular phenotypic features associated with mutations in ADAMTS18. JAMA Ophthalmol. 2014 Aug;132(8):996-1001.
  • Tan LT, Davagnanam I, Isa H, Taylor SR, Rose GE, Verity DH, Pusey CD, Lightman S. Clinical and imaging features predictive of orbital granulomatosis with polyangiitis and the risk of systemic involvement. Ophthalmology. 2014 Jun;121(6):1304-9.
  • Ahmed RM, Murphy E, Davagnanam I, Parton M, Schott JM, Mummery CJ, Rohrer JD, Lachmann RH, Houlden H, Fox NC, Chataway J. A practical approach to diagnosing adult onset leukodystrophies. J Neurol Neurosurg Psychiatry. 2014 Jul;85(7):770-81.
  • Gemmete JJ, Davagnanam I, Toma AK, Brew S, Ganesan V. Arterial ischemic stroke in children. Neuroimaging Clin N Am. 2013 Nov;23(4):781-98.
  • Gemmete JJ, Toma AK, Davagnanam I, Robertson F, Brew S. Pediatric cerebral aneurysms. Neuroimaging Clin N Am. 2013 Nov;23(4):771-9.
  • Toma AK, Davagnanam I, Ganesan V, Brew S. Cerebral arteriovenous shunts in children. Neuroimaging Clin N Am. 2013 Nov;23(4):757-70.
  • Davagnanam I, Toma AK, Brew S. Spinal arteriovenous shunts in children. Neuroimaging Clin N Am. 2013 Nov;23(4):749-56.
  • Luo YH, Davagnanam I, dacCuz L. MRI brain scans in two patients with the argus II retinal prosthesis. Ophthalmology. 2013 Aug;120(8):1711-1711.
  • Ederle J, Davagnanam I, van der Worp HB, Venables GS, Lyrer PA, Featherstone RL, Brown MM, Jäger HR; ICSS investigators. Effect of white-matter lesions on the risk of periprocedural stroke after carotid artery stenting versus endarterectomy in the International Carotid Stenting Study (ICSS): a prespecified analysis of data from a randomised trial. Lancet Neurol. 2013 Sep;12(9):866-872.
  • Storoni M, Davagnanam I, Radon M, Siddiqui A, Plant GT. Distinguishing optic neuritis in neuromyelitis optica spectrum disease from multiple sclerosis: a novel magnetic resonance imaging scoring system. J Neuroophthalmol. 2013 Jun;33(2):123-7.
  • Doherty KM, Davagnanam I, Molloy S, Silveira-Moriyama L, Lees AJ. Pisa syndrome in Parkinson's disease: a mobile or fixed deformity? J Neurol Neurosurg Psychiatry. 2013 Dec;84(12):1400-3.
  • Wilson MH, Davagnanam I, Holland G, Dattani RS, Tamm A, Hirani SP, Kolfschoten N, Strycharczuk L, Green C, Thornton JS, Wright A, Edsell M, Kitchen ND, Sharp DJ, Ham TE, Murray A, Holloway CJ, Clarke K, Grocott MP, Montgomery H, Imray C; Birmingham Medical Research Expeditionary Society and Caudwell Xtreme Everest Research Group. Cerebral venous system and anatomical predisposition to high-altitude headache. Ann Neurol. 2013 Mar;73(3):381-9.
  • Davagnanam I, Fraser CL, Miszkiel K, Daniel CS, Plant GT. Adult Horner's syndrome: a combined clinical, pharmacological, and imaging algorithm. Eye (Lond). 2013 Mar;27(3):291-8.
  • Stevens JC, Murphy SM, Davagnanam I, Phadke R, Anderson G, Nethisinghe S, Bremner F, Giunti P, Reilly MM. The ARSACS phenotype can include supranuclear gaze palsy and skin lipofuscin deposits. J Neurol Neurosurg Psychiatry. 2013 Jan;84(1):114-6.
  • Allouni AK, Davis W, Mankad K, Rankine J, Davagnanam I. Modern spinal instrumentation. Part 2: multimodality imaging approach for assessment of complications. Clin Radiol. 2013 Jan;68(1):75-81.
  • Davis W, Allouni AK, Mankad K, Prezzi D, Elias T, Rankine J, Davagnanam I. Modern spinal instrumentation. Part 1: normal spinal implants. Clin Radiol. 2013 Jan;68(1):64-74.
  • Fraser CL, Davagnanam I, Radon M, Plant GT. The time course and phenotype of Uhthoff phenomenon following optic neuritis. Mult Scler. 2012 Jul;18(7):1042-4.
  • Wilson MH, Edsell ME, Davagnanam I, Hirani SP, Martin DS, Levett DZ, Thornton JS, Golay X, Strycharczuk L, Newman SP, Montgomery HE, Grocott MP, Imray CH; Caudwell Xtreme Everest Research Group. Cerebral artery dilatation maintains cerebral oxygenation at extreme altitude and in acute hypoxia--an ultrasound and MRI study. J Cereb Blood Flow Metab. 2011 Oct;31(10):2019-29.
  • Chaudhary N, Davagnanam I, Ansari SA, Pandey A, Thompson BG, Gemmete JJ. Imaging of intracranial aneurysms causing isolated third cranial nerve palsy. J Neuroophthalmol. 2009 Sep;29(3):238-44. doi: 10.1097/WNO.0b013e3181b415f4. Review. PubMed PMID: 19726948.
  • Davagnanam I, Chavda SV. Identification of the normal jugular foramen and lower cranial nerve anatomy: contrast-enhanced 3D fast imaging employing steady-state acquisition MR imaging. AJNR Am J Neuroradiol. 2008 Mar;29(3):574-6.
  • Blann AD, Tan KT, Tayebjee MH, Davagnanam I, Moss M, Lip GY. Soluble CD40L in peripheral artery disease. Relationship with disease severity, platelet markers and the effects of angioplasty. Thromb Haemost. 2005 Mar;93(3):578-83.