Professional background

Dr Paul Glynne has been consultant physician at UCLH since 2003. Paul studied medicine at University College London, and trained in general medicine, nephrology and critical care at The Hammersmith and University College Hospitals.

He was previously a Wellcome Trust Research fellow at Imperial College and was awarded a PhD for his work on the pathogenesis of acute renal failure in sepsis.

His key interests are in general internal medicine, and difficult diagnostic problems. He leads the acute and general medicine outpatient clinic at UCLH.

The COVID19 pandemic has stimulated a keen interest in post viral syndromes and long COVID. Paul has held a number of senior positions at UCLH including divisional director of emergency services and medical director, medicine board.

Research interests

  • General medicine
  • Difficult diagnostic problems

Publications

  • Long COVID following mild SARS-CoV-2 infection: characteristic T cell alterations and response to antihistamines. Glynne P, Tahmasebi N, Gant V, Gupta R. J Investig Med. 2022 Jan;70(1):61-67. doi:10.1136/jim-2021-002051. Epub 2021 Oct 5.
  • Draw on Expert Opinion to Optimise Care for Long COVID. Dr Harsha Master, Dr Ashish Chaudhry, Dr Nicholas Gall, Dr Louise Newson, Dr Sarah Glynne, and Dr Paul Glynne | 22 June 2022 https://www.medscape.co.uk/viewarticle/draw-expert-opinion-optimise-care-long-covid-2022a1001lla
  • Shamaila Z, Patel B, Glynne P, Vanderpump M, Alsafi A, Khan S, Flora R, Palazzo F and Wernig . A rare cause of severe Cushing’s syndrome. Endocrinology, diabetes and metabolism; 20-0011; March 2020
  • Ciurtin C, Pitiyage G, de Villiers P, Glynne P. Investigating Persistent Bilateral Ankle Swelling. International Archives of Medicine; 2015; 8(238)
  • Tully A, Mayer EK, Glynne P. et al. Bilateral adrenal haemorrhage following cysto-prostatectomy: a case report. Br J Med & Surg Urol 2008; vol1 p85-87. PMID: 34611034
  • A rare cause of severe Cushing's syndrome. Zaman S, Patel B, Glynne P, Vanderpump M, Alsafi A, Khan S, Flora R, Palazzo F, Wernig F. Endocrinol Diabetes Metab Case Rep. 2020 Mar 13;2020:20-0011. doi: 10.1530/EDM-20-0011.
  • Treating critical illness: the importance of first doing no harm. Singer M, Glynne P. PLoS Med. 2005 Jun;2(6):e167. doi: 10.1371/journal.pmed.0020167. Epub 2005 Jun 28. PMID: 15971943
  • Treatment of pulmonary hypertension in the general adult intensive care unit: a role for oral sildenafil? Ng J, Finney SJ, Shulman R, Bellingan GJ, Singer M, Glynne PA. Br J Anaesth. 2005 Jun;94(6):774-7. doi: 10.1093/bja/aei114. Epub 2005 Mar 11. PMID: 15764630
  • Role of the PDZ scaffolding protein in tubule cells in maintenance of polarised function. Glynne PA, Evans TJ. Exp Nephrol. 2002;10(5-6):307-12. doi: 10.1159/000065307. PMID: 12381914.
  • Primary culture of human proximal renal tubular epithelial cells. Glynne PA. Methods Mol Med. 2000;36:197-205. doi: 10.1385/1-59259-216-3:197. PMID: 21340976
  • Coexpressed nitric oxide synthase and apical beta(1) integrins influence tubule cell adhesion after cytokine-induced injury. Glynne PA, Picot J, Evans TJ. J Am Soc Nephrol. 2001 Nov;12(11):2370-2383. doi: 10.1681/ASN.V12112370. PMID: 11675413
  • Inflammatory cytokines induce apoptotic and necrotic cell shedding from human proximal tubular epithelial cell monolayers. Glynne PA, Evans TJ. Kidney Int. 1999 Jun;55(6):2573-97. doi: 10.1046/j.1523-1755.2002.t01-1-00456.x. PMID: 10354308
  • Epithelial inducible nitric-oxide synthase is an apical EBP50-binding protein that directs vectorial nitric oxide output. Glynne PA, Darling KE, Picot J, Evans TJ. J Biol Chem. 2002 Sep 6;277(36):33132-8. doi: 10.1074/jbc.M205764200. Epub 2002 Jun 21. PMID: 12080081
  • Bullous dermatoses in end-stage renal failure: porphyria or pseudoporphyria? Glynne P, Deacon A, Goldsmith D, Pusey C, Clutterbuck E. Am J Kidney Dis. 1999 Jul;34(1):155-60. doi: 10.1016/s0272-6386(99)70123-x.PMID: 10401031
  • Quinine-induced immune thrombocytopenic purpura followed by hemolytic uremic syndrome. Glynne P, Salama A, Chaudhry A, Swirsky D, Lightstone L. Am J Kidney Dis. 1999 Jan;33(1):133-7. doi: 10.1016/s0272-6386(99)70269-6. PMID: 9915279.