Photo of Mr Patrick Grover

Mr Patrick Grover

Telephone:

Email:

Location:

  • National Hospital for Neurology and Neurosurgery

GMC/GDC number:

7016149

Professional background

Mr Grover is the clinical director of neurosurgery at the National Hospital for Neurology and Neurosurgery (NHNN). He is specialised in skull base and vascular neurosurgery. He has particular expertise in the management of tumours of the skull base such as vestibular schwannomas and meningiomas, as well as cerebral aneurysms, AVMs and cavernomas. He is also a practitioner of gamma knife radiosurgery for the minimally invasive treatment of these pathologies.

He undertook undergraduate and postgraduate degrees at Oxford University in Biology, Medicine and Neurosciences. His medical and neurosurgical training was across North London with higher surgical fellowship training at NHNN.

His academic interests are in artificial intelligence and technology applications in surgery, unruptured aneurysm management (the ROAR study), Cavernomas (the CARE trial) and multimodal AVM management. He is co-investigator in the Queen Square TeQ group.

He is a director of the Queen Square simulation centre and the Queen Square review course.

Specialties

Research interests

  • Unruptured aneurysm management
  • AVM registries and biology
  • Artificial intelligence and technology applications in skull base tumour surgery

Publications

Senior author

  • Lasica AB, Tancu C, Abussuud ZA, Watkins LD, Grover PJ. Communicating hydrocephalus following stereotactic radiosurgery for periventricular meningiomas: illustrative cases. J Neurosurg Case Lessons 2025 Jan 20;9(3):CASE24722. doi: 10.3171/CASE24722. PMID: 39832307.
  • Williams, S.C., Noor, K., Sinha, S., Dobson, R.J., Searle, T., Funnell, J.P., Hanrahan, J.G., Muirhead, W.R., Kitchen, N., Kanona, H., Khalil, S., Saeed, S.R., Marcus, H.J., & Grover, P. (2023). Concept Recognition and Characterization of Patients Undergoing Resection of Vestibular Schwannoma Using Natural Language Processing. Journal of Neurological Surgery Part B: Skull Base.
  • Sinha S, Williams SC, Hanrahan JG, Muirhead WR, Booker J, Khalil S, Kitchen N, Newall N, Obholzer R, Saeed SR, Marcus HJ, Grover P. Mapping the Clinical Pathway for Patients Undergoing Vestibular Schwannoma Resection. World Neurosurg. 2024 27:S1878-8750(24)01297-X. doi: 10.1016/j.wneu.2024.07.157. PMID: 39074584.
  • Starup-Hansen J, Williams SC, Valetopoulou A, Khan DZ, Horsfall HL, Moudgil-Joshi J, Burton O, Kanona H, Saeed SR, Muirhead W, Marcus HJ, Grover P. Skull Base Repair following Resection of Vestibular Schwannoma: A Systematic Review (Part 1: The Retrosigmoid Approach). J Neurol Surg B Skull Base. 2024 Jan 22;85(Suppl 2):e117-e130. doi: 10.1055/a-2222- 0184. PMID: 39444767; PMCID: PMC11495915.
  • Starup-Hansen J, Williams SC, Valetopoulou A, Khan DZ, Horsfall HL, Moudgil-Joshi J, Burton O, Kanona H, Saeed SR, Muirhead W, Marcus HJ, Grover P. Skull Base Repair following Resection of Vestibular Schwannoma: A Systematic Review (Part 2: The Translabyrinthine Approach). J Neurol Surg B Skull Base. 2024 Jan 22;85(Suppl 2):e131-e144. doi: 10.1055/a2222-0016. PMID: 39444760; PMCID: PMC11495917.
  • Layard Horsfall H, Khan DZ, Collins J, Cooke S, Freeman SR, Gurusinghe N, Hampton S, Hardwidge C, Irving R, Kitchen N, King A, Khalil S, Koh CH, Leonard C, Marcus HJ, Muirhead W, Obholzer R, Pathmanaban O, Robertson IJA, Shapey J, Stoyanov D, Teo M, Tysome JR, Saeed SR, Grover P. Generating Operative Workflows for Vestibular Schwannoma Resection: A TwoStage Delphi's Consensus in Collaboration with the British Skull Base Society. Part 1: The Retrosigmoid Approach. J Neurol Surg B Skull Base. 2022 Oct 10;84(5):423-432. doi: 10.1055/a-1886-5500. PMID: 37671298; PMCID: PMC10477012.
  • Horsfall HL, Khan DZ, Collins J, Cooke S, Freeman SR, Gurusinghe N, Hampton S, Hardwidge C, Irving R, Kitchen N, King A, Khalil S, Koh CH, Leonard C, Marcus HJ, Muirhead W, Obholzer R, Pathmanaban O, Robertson IJA, Shapey J, Stoyanov D, Teo M, Tysome JR, Grover P, Saeed SR. Generating Operative Workflows for Vestibular Schwannoma Resection: A Two-Stage Delphi's Consensus in Collaboration with the British Skull Base Society. Part 2: The Translabyrinthine Approach. J Neurol Surg B Skull Base. 2022 Oct 10;84(5):433-443. doi: 10.1055/s-0042-1755578. PMID: 37671296; PMCID: PMC10477015.
  • Williams SC, Ahmed R, Davids JD, Funnell JP, Hanrahan JG, Layard Horsfall H, Muirhead W, Nicolosi F, Thorne L, Marcus HJ, Grover P. Benchtop simulation of the retrosigmoid approach: Validation of a surgical simulator and development of a taskspecific outcome measure score. World Neurosurg X. 2023 Jun 24;20:100230. doi: 10.1016/j.wnsx.2023.100230. PMID: 37456690; PMCID: PMC10344945
  • China M, Vastani A, Hill CS, Tancu C, Grover PJ. Gamma Knife radiosurgery for cerebral arteriovenous malformations: a systematic review and meta-analysis. Neurosurg Rev. 2022 Jun;45(3):1987-2004. doi: 10.1007/s10143-022-01751-1. Epub 2022 Feb 18. PMID: 35178626; PMCID: PMC9160151.

First author

  • Grover PJ, Harris LS, Qureshi AM, Rennie A, Robertson F, James G. Occult posterior inferior cerebellar artery dissection requiring endovascular treatment following pediatric head trauma: case report. J Neurosurg Pediatr (2021). Doi: 10.3171/2020.11.PEDS18324. PMID 33836497.
  • Grover PJ, Harris LS, Thompson DNP. Craniocervical junction fixation in children less than 5 years. Eur Spine J (2020). doi: 10.1007/s00586-020-06313-x. PMID: 32016540.
  • Grover PJ, Pushpananthan S, Samarage HM, Mendoza, ND. Obesity and posterior spinal fat content: impact on complications in non-complex lumbar spine surgery. Br J Neurosurg (2017). doi: 10.1080/02688697.2016.1220502. PMID: 27550527.
  • Grover PJ*, De Simoni S*, Jenkins P, Scott G, Ross E, Honeyfield L, Waldman A, Patel M, Wilson M, Sharp, DJ. Disconnection between the Default Mode Network and Medial Temporal Lobes in Post-Traumatic Amnesia. Brain (2016). doi 10.1093/brain/aww241. PMID: 27797805. * (joint first authorship)
  • Grover PJ, Bradford R, Saeed S. Bilateral Vestibular Schwannomas associated with Neurofibromatosis Type 2. Challenging Concepts in Neurosurgery. Eds Bhatia R, Sabin I. 2015. Grover PJ, Jayaram R, Madder H. Management of cerebral venous thrombosis in a patient with Lane-Hamilton syndrome and CEC syndrome. Br J Neurosurg (2010). doi: 10.3109/02688697.2010.500412. PMID: 21070152
  • Grover PJ, Pereira EA, Peterson D. Neurosurgery as a first foundation year post. Br J Neurosurg (2010). doi: 10.3109/02688697.2010.487382. PMID: 20465464. Article commentary by Richard Nelson. 2010; 24(3): 314.
  • Grover PJ. Thalamic tumour presenting with tremor: diagnostic difficulties. BMJ case reports (2010). doi: 10.1136/bcr.11.2009.2432. PMID: 22736217. (Editor’s choice of the week Sept 2010).
  • Grover PJ, Pereira EA, Green AL, Brittain JS, Owen SL, Schweder P, Kringelbach ML, Davies PT, Aziz TZ. Deep brain stimulation for cluster headache. J Clin Neurosci (2009). doi: 10.1016/j.jocn.2008.10.012. PMID: 19398342

National collaboratives

  • CARE pilot trial collaboration. Medical management and surgery versus medical management alone for symptomatic cerebral cavernous malformation (CARE): a feasibility study and randomised, open, pragmatic, pilot phase trial. Lancet Neurol. 2024 Jun;23(6):565-576. doi: 10.1016/S1474-4422(24)00096-6. Epub 2024 Apr 18. PMID: 38643777.
  • Loan JJM, Bacon A, van Beijnum J, Bhatt P, Bjornson A, Broomes N, Bullen A, Bulters D, Cahill J, Chavredakis E, Colombo F, Danciut M, Digpal R, Edwards RJ, Ferguson L, Forsyth L, Fouyas I, Ganesan V, Grover P, Gurusinghe N, Hall PS, Harkness K, Harris LS, Hayton T, Helmy A, Holsgrove D, Hutchinson PJ, Israni A, Kinsella E, Lewis S, Majeed S, Mallucci C, Mukerji N, Nair R, Neilson AR, Papadopoulos MC, Radatz M, Rossdeutsch A, Raza-Knight S, Stephen J, Stoddart A, Teo M, Turner C, Wade J, Walsh D, White D, White P, Wildman J, Wroe Wright O, Uff C, Ushewokunze S, Vindlacheruvu R, Kitchen N, Al-Shahi Salman R; Cavernomas A Randomised Effectiveness (CARE) pilot trial collaborators. Feasibility of comparing medical management and surgery (with neurosurgery or stereotactic radiosurgery) with medical management alone in people with symptomatic brain cavernoma - protocol for the Cavernomas: A Randomised Effectiveness (CARE) pilot trial. BMJ Open. 2023 Aug 9;13(8):e075187. doi: 10.1136/bmjopen-2023-075187. PMID: 37558454; PMCID: PMC10414059.
  • Galea I, Bandyopadhyay S, Bulters D, Humar R, Hugelshofer M, Schaer DJ; SAH Delphi Group. Haptoglobin Treatment for Aneurysmal Subarachnoid Hemorrhage: Review and Expert Consensus on Clinical Translation. Stroke. 2023 Jul;54(7):1930- 1942. doi: 10.1161/STROKEAHA.123.040205. Epub 2023 May 26. PMID: 37232189; PMCID: PMC10289236.
  • Hall S, Birks J, Anderson I, Bacon A, Brennan PM, Bennett D, Chavredakis E, Critchley G, Dow G, Downer J, Galea J, Grover P, Gurusinghe N, Helmy A, Kounin G, Mukerji N, Patel H, Patel J, Ross N, St George J, Teo M, Tolias CM, Tzerakis N, Uff C, van Beijum J, Veighey K, White E, Whitfield P, Bulters DO; ROAR Investigators. Risk of Aneurysm Rupture (ROAR) study: protocol for a long-term, longitudinal, UK multicentre study of unruptured intracranial aneurysms. BMJ Open. 2023 Mar 16;13(3):e070504. doi: 10.1136/bmjopen-2022-070504. PMID: 36927598; PMCID: PMC10030903.
  • Hannan CJ, Islim AI, Alalade AF, Bacon A, Ghosh A, Dalton A, Abouharb A, Walsh DC, Bulters D, White E, Chavredakis E, Kounin G, Critchley G, Dow G, Patel HC, Brydon H, Anderson IA, Fouyas I, Galea J, St George J, Bal J, Patel K, Kamel M, Teo M, Fanning N, Mukerji N, Grover P, Mitchell P, Whitfield PC, Trivedi R, Crockett MT, Brennan P, Javadpour M. Radiological follow-up of endovascularly treated intracranial aneurysms: a survey of current practice in the UK and Ireland. Acta Neurochir (Wien). 2023 Feb;165(2):451-459. doi: 10.1007/s00701-022-05379-4. Epub 2022 Oct 11. PMID: 36220949.

Other

  • Williams SC, Zhou J, Muirhead WR, Khan DZ, Koh CH, Ahmed R, Funnell JP, Hanrahan JG, Ali AM, Ghosh S, Sarıdoğan T, Valetopoulou A, Grover P, Stoyanov D, Murphy M, Mazomenos EB, Marcus HJ. Artificial Intelligence Assisted Surgical Scene Recognition: A Comparative Study Amongst Healthcare Professionals. Ann Surg. 2024 Oct 30. doi: 10.1097/SLA. Epub ahead of print. PMID: 39474680.
  • Shapey J, Vos SB, Mancini L, Sanders B, Thornton JS, Tournier JD, Saeed SR, Kitchen N, Khalil S, Grover P, Bradford R, Dorent R, Sparks R, Vercauteren T, Yousry T, Bisdas S, Ourselin S. Diffusion MRI of the facial-vestibulocochlear nerve complex: a prospective clinical validation study. Eur Radiol. 2023 Nov;33(11):8067-8076. doi: 10.1007/s00330-023-09736-4. Epub 2023 Jun 17. PMID: 37328641; PMCID: PMC10598116.
  • Ahmed R, Muirhead W, Williams SC, Bagchi B, Datta P, Gupta P, Salvadores Fernandez C, Funnell JP, Hanrahan JG, Davids JD, Grover P, Tiwari MK, Murphy M, Marcus HJ. A synthetic model simulator for intracranial aneurysm clipping: validation of the UpSurgeOn AneurysmBox. Front Surg. 2023 May 31;10:1185516. doi: 10.3389/fsurg.2023.1185516. PMID: 37325417; PMCID: PMC10264641.
  • Hill CS, Borg A, Horsfall HL, Al-Mohammad A, Grover P, Kitchen N. Cerebral cavernous malformation: Management, outcomes, and surveillance strategies - A single centre retrospective cohort study. Clin Neurol Neurosurg. 2023 Feb;225:107576. doi: 10.1016/j.clineuro.2022.107576. Epub 2022 Dec 26. PMID: 36608471.
  • Harris PJ, Poorthuis M, Grover PJ, Kitchen N, Al-Shahi R. Surgery for cerebral cavernous malformations: A systematic review and meta-analysis. Neurosurg Rev. (2022).
  • Muirhead WR, Layard Horsfall H, Khan DZ, Koh C, Grover PJ, Toma AK, Castanho P, Stoyanov D, Marcus HJ, Murphy M. Microsurgery for intracranial aneurysms: A qualitative survey on technical challenges and technological solutions. Front Surg. 2022 Aug 4;9:957450. doi: 10.3389/fsurg.2022.957450. PMID: 35990100; PMCID: PMC9386123.
  • Shapey J, Xie Y, Nabavi E, Ebner M, Saeed SR, Kitchen N, Dorward N, Grieve J, McEvoy AW, Miserocchi A, Grover P, Bradford R, Lim YM, Ourselin S, Brandner S, Jaunmuktane Z, Vercauteren T. Optical properties of human brain and tumour tissue: An ex vivo study spanning the visible range to beyond the second near-infrared window. J Biophotonics. 2022 Apr;15(4):e202100072. doi: 10.1002/jbio.202100072. Epub 2022 Feb 12. PMID: 35048541.
  • Layard Horsfall H, Toescu SM, Grover PJ, Hassell J, Sayer C, Hemingway C, Harding B, Jacques TS, Aquilina K. The utility of brain biopsy in pediatric cryptogenic neurological disease. J Neurosurg Pediatr (2020). doi: 10.3171/2020.4.PEDS19783. PMID: 32619987.
  • Muirhead, W, Grover PJ, Toma A, Stoyanov D, Marcus H, Murphy M. Adverse intraoperative events during surgical repair of ruptured cerebral aneurysms. A systematic review. Neurosurg Rev (2020). doi: 10.1007/s10143-020-01312-4. PMID: 32542428.
  • Lo, WB, McAuley, CP, Gillies, MJ, Grover, PJ, Pereira, EAC. Consent: an event or a memory in lumbar spine surgery? A multicentre, multi-speciality prospective study of documentation and patient recall of consent content. Eur Spine J (2017). doi: 10.1007/s00586-017-5107-6. PMID 28528481.
  • Brennan PM, Kolias AG, Joannides AJ, Shapey J, Marcus HJ, Gregson BA, Grover P, Hutchinson PJ, Coulter IC. The management and outcome of patients with chronic subdural haematoma: a prospective, multi-centre observational cohort study in the United Kingdom. J Neurosurg (2017). doi: 10.3171/2016.8.JNS16134. PMID: 28306417.
  • Siddiqui J, Grover PJ, Makalanda HL, Campion T, Bull J, Adams A. The spectrum of traumatic injuries at the craniocervical junction: a review of imaging findings and management. Emerg Radiol (2017). doi: 10.1007/s10140-017-1490-x. PMID 28243764.
  • Hughes MA, Grover PJ, Butler CR, Elwell, VA, Mendoza, ND. A 5-Year retrospective study assessing the association between seasonal and meteorological change and incidence of aneurysmal subarachnoid haemorrhage. Br J Neurosurg (2010). doi: 10.3109/02688697.2010.499154. PMID: 20726749

Abstracts

  • Grover PJ, Kafai-Golahmadi A, Layard-Horsfall H, Toma, A, Grieve, J, Watkins, L, Kitchen, N, Murphy, M. Arteriovenous malformations (AVMs): changing practice over 10 years and a proposal for a national registry. JNNP. March 2019 vol 90-3.
  • Draz MS, Toma AK, Bezouich S, Grover, PJ. Endovascular versus surgical management of pericallosal artery aneurysms, single centre experience. JNNP. March 2019 vol 90-3.
  • Borg A, Schmitt A, Grover P, Toma A, Robertson F. Predictors of retreatment of anterior communicating artery aneurysms after endovascular embolisation. JNNP. March 2019 vol 90-3.
  • Jenkins P, De Simoni S, Grover P, Waldman A, Sharp D. Hippocampal connectivity and post traumatic amnesia. JNNP. Sep 2014; 85: e4. 7
  • Vivekanantham, S, Siddiqui A, Grover PJ, Mendoza N. Changing patterns in referral, bed state and length of stay. B J Neurosurg. Apr 2014; 28(2);153.
  • Grover PJ, Pushpananthan, S, Samarage, H, Mendoza ND. Does excess posterior spinal fat lead to more perioperative complications in lumbar spine surgery. Br J Neurosurg. 2012. 26 (5); 596.
  • Grover PJ, Lamb J, Pywell M, Thorne L. Preventing surgical site infection in neurosurgery: a four year audit. Intl J Surg. 2012. 10 (8), S51.
  • Grover PJ, Macgregor R, Metcalfe MJ, Franklin IJ, Davies AH. Blood product preparation and usage in EVAR. Intl J Surg. 2010. 8 (7), 545.
  • Grover PJ, Butler CR, Hughes MA, Peterson D. Head injury referral patterns to a UK neurosurgical unit. B J Neurosurg. Jan 2009, 23(2);136.