Professional background

Qualified from Cambridge and St Bartholomew's Hospital 1971.

Postgrad posts at UCLH, St Barts, Harvard Med School, Hammersmith Hospital and the Royal Marsden.  A consultant at UCLH since 1981 and professor of cancer medicine since 2002. MD Thesis (Cantab)1977.  

Author of "Cancer and its Management", a standard international text, now in its 6th Edn, and six other books, two for the general public. 

Board member of Cancer Research UK since 1991.  Previous member of the BMJ ethics committee and previous clinical director of oncology at UCLH, 1992- 1998. 

Past president of the British Association for Head and Neck Oncology


Research interests

Breast cancer, myeloma, gynaecological and upper gastro-enterological cancers.


Multiple papers on innovative techniques of treatment for breast cancer, lung, head and neck and g-i cancers,  ethics of innovative treatments.  Various textbooks.   Fuller listing in " Who's Who "  2010.

Most recent original research papers include :

1.Long-term Results of Targeted Intraoperative Radiotherapy (Targit) Boost during Breast-conserving Surgery.
Vaidya JS, Baum M, Tobias JS,  et al.   Int J Radiat Oncol Biol Phys. 2010 Oct 15. [Epub ahead of print]

2.The ATAC adjuvant breast-cancer trial: six-year results of the endometrial subprotocol.
Duffy S, Jackson TL, Lansdown M, Philips K, Wells M, Clack G, Bianco AR et al, for the ATAC Trialists' Group.
J Obstet Gynaecol. 2010;30(6):596-604.

3.Targeted Intraoperative Radiotherapy for Breast Cancer in Patients in Whom External Beam Radiation Is Not Possible.
Keshtgar MR, Vaidya JS, Tobias JS, et al.  Int J Radiat Oncol Biol Phys. 2010 Jun 18. [Epub ahead of print]

4.Response to "Intraoperative radiotherapy in early-stage breast cancer: results of the Montpellier phase II trial."(Int J Radiat Oncol Biol Phys May 2009).
Vaidya JS, Tobias JS, Baum M, Keshtgar M, Williams N, Wenz F, Joseph D.
Int J Radiat Oncol Biol Phys. 2010 Jul 15;77(4):1289; author reply 1289.

5.Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial.
Vaidya JS, Joseph DJ, Tobias JS,  et al.  Lancet. 2010 Jul 10;376(9735):91-102.

6.Chemoradiotherapy for locally advanced head and neck cancer: 10-year follow-up of the UK Head and Neck (UKHAN1) trial.
Tobias JS, Monson K, Gupta N, Macdougall H, Glaholm J, Hutchison I, Kadalayil L, Hackshaw A; UK Head and Neck Cancer Trialists' Group.
Lancet Oncol. 2010 Jan;11(1):66-74. Epub 2009 Oct 29.

7.Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients.
Pignon JP, le Maître A, Maillard E, Bourhis J et al for the MACH-NC Collaborative Head and Neck Cancer Group.
Radiother Oncol. 2009 Jul;92(1):4-14. Epub 2009 May 14.