Professional background

Professor Nick Fox's first degree was in Physics and Physiology from Cambridge. He subsequently graduated with honours in medicine from the University of London and then specialised in cognitive neurology. He held research fellowships from the Alzheimer's Society and the Medical Research Council (MRC).

He is currently professor of neurology and director of the Dementia Research Centre at the UCL Insitute of Neurology, Queen Square, London, and a consultant neurologist in the Cognitive Disorders Clinic. He co-leads Rare Dementia Support which provides support, help and advice on less common, young onset and inherited dementias.

He is a member of the Research Strategy Council of the Alzheimer’s Society.

His clinical interests are focused on young onset and familial dementias. His research is aimed at improving diagnosis and treatment of cognitive problems.

Research interests

Young onset dementia, familial Alzheimer's disease, inherited dementias, imaging, diagnosis


  • Ryan NS, Nicholas JM, Weston PS, Liang Y, Lashley T, Guerreiro R, Adamson G, Kenny J, Beck J, Chavez-Gutierrez L, de Strooper B, Revesz T, Holton J, Mead S, Rossor MN, Fox NC. Clinical phenotype and genetic associations in autosomal dominant familial AD. Lancet Neurology. 2016;15(13):1326-1335.
  • Crutch SJ, Lehamnn M, Schott JM, Rabinovici GD, Rossor MN, Fox NC. Posterior cortical atrophy. Lancet Neurol 2012 Feb;11(2):170-8. PMID: 22265212
  • Seelaar H, Rohrer JD, Pijnenburg YA, Fox NC, van Swieten Jc. Clinical genetic and pathological heterogeneity of frontotemporal dementia: a review. J Neurol Neurosurg Psychiatry. 2011 May;82(5):476-86. PMID: 20971753
  • Dubois B, Feldman HH, Jacova C, Cummings JL, Dekosky ST, Barberger-Gateau P, Delacourte A, Frisoni G, Fox NC, Galasko D, Gauthier S, Hampel H, Jicha GA, Meguro K, O'Brien J, Pasquier F, Robert P, Rossor M, Salloway S, Sarazin M, de Souza LC, Stern Y, Visser PJ, Scheltens P. Revising the definition of Alzheimer's disease: a new lexicon. Lancet Neurol. 2010 Nov;9(11):1118-27. PMID: 20934914
  • Rossor MN, Fox NC, Mummery CJ, Schott JM, Warren JD. The diagnosis of young-onset dementia. Lancet Neurol 2010 Aug 9(8):793-806. PMID: 20650401
  • Ridha BH, Barnes J, Bartlett JW, Godbolt A, Pepple T, Rossor MN, Fox NC. Tracking atrophy progression in familial Alzheimer’s disease: a serial MRI study. Lancet Neurology 2006 Oct;5(10):828-34. PMID: 16987729
  • Chan D, Janssen JC, Whitwell JL, Watt HC, Jenkins R, Frost C, Rossor MN, Fox NC. Change in rates of cerebral atrophy over time in early-onset Alzheimer’s disease: longitudinal MRI study. Lancet 2003 Oct 4;362:1121-1122. PMID: 14550701
  • Fox NC, Black RS, Gilman S, Rossor MN, Griffith SG, Jenkins L, Koller M. Effects of A? immunization (AN1792) on MRI measures of cerebral volume in Alzheimer’s disease. Neurology 2005 May;64(9):1563-72. PMID: 15883317
  • Schott JM, Fox NC, Frost C, Scahill RI, Janssen JC, Chan D, Jenkins R, Rossor MN. Assessing the onset of structural change in familial Alzheimer’s disease. Annals of Neurology 2003 Feb;53(2):181-8. PMID: 12557284
  • Longitudinal measurement of serum neurofilament light in presymptomatic familial Alzheimer's disease. Weston PSJ, Poole T, O'Connor A, Heslegrave A, Ryan NS, Liang Y, Druyeh R, Mead S, Blennow K, Schott JM, Frost C, Zetterberg H, Fox NC. Alzheimers Res Ther. 2019 Feb 20;11(1):19. doi: 10.1186/s13195-019-0472-5.PMID: 30786919
  • Plasma phospho-tau181 in presymptomatic and symptomatic familial Alzheimer's disease: a longitudinal cohort study. O'Connor A, Karikari TK, Poole T, Ashton NJ, Lantero Rodriguez J, Khatun A, Swift I, Heslegrave AJ, Abel E, Chung E, Weston PSJ, Pavisic IM, Ryan NS, Barker S, Rossor MN, Polke JM, Frost C, Mead S, Blennow K, Zetterberg H, Fox NC.Mol Psychiatry. 2020 Jul 14. doi: 10.1038/s41380-020-0838-x. Online ahead of print. PMID: 32665603