Professor Janes won an MRC Training fellowship to perform a PhD and then a post-doctoral period working in the CRUK Lincoln’s Inn Fields Institute with Fiona Watt working on integrin adhesion molecules and cancer cell survival. He then moved as an MRC Clinician Scientist to UCL leading a group interested in the role of stem cells in lung cancer pathogenesis and treatment of lung disease using cell therapies.
He was awarded a Wellcome Trust Senior Clinical fellowship in October 2010 to work on novel cell therapies for lung cancers resulting in a DPFS first-in-man award and recently won his Wellcome Senior fellowship renewal to study the genetic and cellular changes lung cancer pathogenesis. The ambition is that from this knowledge he can develop therapies detecting and targeting early lung cancers and thereby dramatically improve outcomes. He works as a respiratory consultant at UCLH with a particular interest in Lung Cancer, mesothelioma, interventional and diagnostic bronchoscopy and early lung cancer detection.
He is head of the respiratory research department at UCL, director of the Lung Cancer Board for London Cancer, lead for Pulmonary at the International Society of Cellular Therapies and Vice-Chair of the National ‘Clinical Expert Group’ on Lung Cancer.
Dr Janes runs the UCLH lung cancer team and has a clinic (SJ41A) on Monday afternoons. He has developed a new endobronchial ultrasound service and performs all the invasive bronchoscopic techniques. He is running several clinical trials aiming to improve the patient journey of diagnosis and staging of lung cancers. These trials include a number of innovative techniques. He works as a consultant for the NHS in respiratory and general medicine with a particular interest in lung cancer, mesothelioma, bronchoscopy and early lung cancer detection.
Over 150 publications including in Nature, Science, and the New England Journal