Professor Shakeel Saeed
Telephone:
Email:
Location:
- University College Hospital
- National Hospital for Neurology and Neurosurgery
- Royal National ENT and Eastman Dental Hospitals
GMC/GDC number:
3097663
Professional background
Graduated from King’s College, London 1985.
Doctorate thesis awarded in 2003.
Previous consultant ENT and skullbase surgeon in Manchester 1999-2008.
Professorial appointment in London since 2008.
Extensive experience in lateral skullbase surgery and implantation otology – leading UK opinion in this field.
- Over 2000 complex ear surgeries
- Over 450 cochlear implant surgeries
- Over 500 vestibular schwannoma (acoustic neuroma) and other skullbase surgeries
- 26 auditory brainstem implant surgeries (adults and children)
President of the European Academy of Otology and Neurotology 2018-2021
President of the Royal Society of Medicine, Section of Otology 2013-2014
President of the British Skullbase Society 2013-2015
President of the British Society of Academic Otorhinolaryngology 2011-2016
Vice-President of the British Cochlear Implant Group 2011-2015
Chairman of the BACO 2015 Academic committee
Collegium Oto-Rhino-Laryngologicum Amicitiae Sacrum (by nomination)
Administrative Advisory Board of JIAO
Medicine and Clinical Trials Group lead, UCL Ear Institute.
Active in otological research and peer review
- Over 120 peer-reviewed publications
- Over 250 presentations and scientific meetings nationally and internationally
Professor Saeed is currently a leading surgeon and researcher in disorders of the ear, hearing, balance, facial nerve and skullbase. He manages patients from all over the UK as well as internationally. This includes adults, children or infants with:
- Hearing loss
- Dizziness
- Tinnitus
- Facial palsy
- Vestibular schwannoma (acoustic neuroma)
- Glomus tumour
- Cholesteatoma
- Otosclerosis
- Facial nerve tumours
- Superior semicircular canal dehiscence
- Meniere’s Disease
- Benign Positional Vertigo
- Hearing loss requiring cochlear implantation
- Hearing loss requiring middle ear implants
Research interests
Outcomes in lateral skullbase surgery and cochlear implantation
Discovery science in cochlear implants, vestibular regeneration, facial palsy and enhancing outcomes of surgery.
Publications
Manual segmentation versus semi-automated segmentation for quantifying vestibular schwannoma volume on MRI.McGrath H, Li P, Dorent R, Bradford R, Saeed S, Bisdas S, Ourselin S, Shapey J, Vercauteren T.Int J Comput Assist Radiol Surg. 2020 Sep;15(9):1445-1455
Unilateral Cochlear Implants for Severe, Profound, or Moderate Sloping to Profound Bilateral Sensorineural Hearing Loss: A Systematic Review and Consensus Statements. Buchman CA, Gifford RH, Haynes DS, Lenarz T, O'Donoghue G, Adunka O, Biever A, Briggs RJ, Carlson ML, Dai P, Driscoll CL, Francis HW, Gantz BJ, Gurgel RK, Hansen MR, Holcomb M, Karltorp E, Kirtane M, Larky J, Mylanus EAM, Roland JT Jr, Saeed SR, Skarzynski H, Skarzynski PH, Syms M, Teagle H, Van de Heyning PH, Vincent C, Wu H, Yamasoba T, Zwolan , JAMA Otolaryngol Head Neck Surg. 2020 Aug 27
Squamous cell cancer of the temporal bone: a review of the literature.Lechner M, Sutton L, Murkin C, Masterson L, O'Flynn P, Wareing MJ, Tatla T, Saeed S.Eur Arch Otorhinolaryngol. 2020 Aug 31
Bioinspired Multiresonant Acoustic Devices Based on Electrospun Piezoelectric Polymeric Nanofibers.
Viola G, Chang J, Maltby T, Steckler F, Jomaa M, Sun J, Edusei J, Zhang D, Vilches A, Gao S, Liu X,Saeed S, Zabalawi H, Gale J, Song W.ACS Appl Mater Interfaces. 2020 Aug 5;12(31):34643-34657
Patient-Specific Polyvinyl Alcohol Phantom Fabrication with Ultrasound and X-Ray Contrast for Brain Tumor Surgery Planning. Mackle EC, Shapey J, Maneas E, Saeed SR, Bradford R, Ourselin S, Vercauteren T, Desjardins AE.J Vis Exp. 2020 Jul 14;(161)
A narrative review of the logistic and economic feasibility of cochlear implants in lower-income countries.
Bodington E, Saeed SR, Smith MCF, Stocks NG, Morse RP.Cochlear Implants Int. 2020 Jul 16:1-10
Hearing Preservation Outcomes With Standard Length Electrodes in Adult Cochlear Implantation and the Uptake of Electroacoustic Stimulation. Harrison L, Manjaly JG, Ellis W, Lavy JA, Shaida A, Khalil SS, Saeed SR.Otol Neurotol. 2020 Jun 19
An artificial intelligence framework for automatic segmentation and volumetry of vestibular schwannomas from contrast-enhanced T1-weighted and high-resolution T2-weighted MRI. Shapey J, Wang G, Dorent R, Dimitriadis A, Li W, Paddick I, Kitchen N, Bisdas S, Saeed SR, Ourselin S, Bradford R, Vercauteren T.J Neurosurg. 2019 Dec 6:1-9.
Physiology of cerebrospinal fluid circulation. Shapey J, Toma A, Saeed SR.Curr Opin Otolaryngol Head Neck Surg. 2019 Oct;27(5):326-333.
The potential for machine learning to improve precision medicine in cochlear implantation.Saeed HS, Stivaros SM, Saeed SR.Cochlear Implants Int. 2019 Sep;20(5):229-230.
Is There a Difference in Hospital Stay between Patients undergoing Translabyrinthine or Retrosigmoid Surgery for Vestibular Schwannoma Stratified by Tumor Size? Visagan R, Hall A, Bradford R, Khalil S, Saeed SR.J Neurol Surg B Skull Base. 2019 Jun;80(3):310-315
Intraoperative multispectral and hyperspectral label-free imaging: A systematic review of in vivo clinical studies.
Shapey J, Xie Y, Nabavi E, Bradford R, Saeed SR, Ourselin S, Vercauteren T.J Biophotonics. 2019 Sep;12(9):
Clinical Applications for Diffusion MRI and Tractography of Cranial Nerves Within the Posterior Fossa: A Systematic Review Shapey J, Vos SB, Vercauteren T, Bradford R, Saeed SR, Bisdas S, Ourselin S.Front Neurosci. 2019 Feb 7;13:23
The Epidemiology of Otosclerosis in a British Cohort. Crompton M, Cadge BA, Ziff JL, Mowat AJ, Nash R, Lavy JA, Powell HRF, Aldren CP, Saeed SR, Dawson SJ.Otol Neurotol. 2019 Jan;40(1):22-30
Evaluation of Possible Effects of a Potassium Channel Modulator on Temporal Processing by Cochlear Implant Listeners. Carlyon RP, Deeks JM, Guérit F, Lamping W, Billig AJ, Large CH, Saeed SR, Harris P.J Assoc Res Otolaryngol. 2018 Dec;19(6):669-680.
Hearing Preservation With Standard Length Electrodes in Pediatric Cochlear Implantation. Manjaly JG, Nash R, Ellis W, Britz A, Lavy JA, Shaida A, Saeed SR, Khalil SS.Otol Neurotol. 2018 Oct;39(9):1109-1114
The Future of Cochlear Implant Design. Mitchell-Innes A, Saeed SR, Irving R.Adv Otorhinolaryngol. 2018;81:105-113
Evidence of distinct RELN and TGFB1 genetic associations in familial and non-familial otosclerosis in a British population. Mowat AJ, Crompton M, Ziff JL, Aldren CP, Lavy JA, Saeed SR, Dawson SJ.Hum Genet. 2018 May;137(5):357-363.
Post-stapedectomy granuloma: a devastating complication. Watts E, Powell HRF, Saeed SR, Irving RM.J Laryngol Otol. 2017 Jun;131(6):557-560.
Outcomes of Transmastoid Surgery for Superior Semicircular Canal Dehiscence Syndrome. Powell HR, Khalil SS, Saeed SR.Otol Neurotol. 2016 Aug;37(7):e228-33
Cochlear implantation in X-linked deafness - How to manage the surgical challenges. Saeed H, Powell HR, Saeed SR.Cochlear Implants Int. 2016 Jul;17(4):178-183.
Mutations and altered expression of SERPINF1 in patients with familial otosclerosis. Ziff JL, Crompton M, Powell HR, Lavy JA, Aldren CP, Steel KP, Saeed SR, Dawson SJ.Hum Mol Genet. 2016 Jun 15;25(12):2393-2403.
Transoral orthodromic temporalis muscle transfer technique for dynamic reanimation of the paralysed face.
Leong SC, Lesser TH, Andrews P, Saeed SR.Clin Otolaryngol. 2016 Dec;41(6):831-833.
A prospective 4-year study of the objective and subjective outcomes of fifteen patients after dynamic facial reanimation surgery. Andrews P, Randhawa PS, Joseph J, Goh S, Li Q, Poirrier AL, Leong S, Lesser T, Saeed SR.Clin Otolaryngol. 2016 Dec;41(6):825-829
Characterizing human vestibular sensory epithelia for experimental studies: new hair bundles on old tissue and implications for therapeutic interventions in ageing. Taylor RR, Jagger DJ, Saeed SR, Axon P, Donnelly N, Tysome J, Moffatt D, Irving R, Monksfield P, Coulson C, Freeman SR, Lloyd SK, Forge A.Neurobiol Aging. 2015 Jun;36(6):2068-84.
Venous thromboembolism prophylaxis in ENT surgery: a survey of current practice. Nash R, Randhawa N, Saeed SR.J Laryngol Otol. 2015 Feb;129(2):164-7.
The use of cone-beam computed tomography to determine cochlear implant electrode position in human temporal bones. Saeed SR, Selvadurai D, Beale T, Biggs N, Murray B, Gibson P, Risi F, Boyd P.Otol Neurotol. 2014 Sep;35(8):1338-44
Cochlear implantation in the mouse via the round window: effects of array insertion. Mistry N, Nolan LS, Saeed SR, Forge A, Taylor RR.Hear Res. 2014 Jun;312:81-90.