Research interests

  • Prevention of brain damage in vulnerable neonates
  • Pain processing in newborns on intensive care
  • Measurement of cerebral blood flow


Duncan A, Meek JH, Elwell CE, Tyscszuk L, Clemence M, Cope M, Wyatt JS, and Delpy DT.
Measurement of optical pathlength as a function of age using phase resolved near infrared spectroscopy. 1995. Ped Res 39:889-894

Meek JH, Elwell CE, Khan MJ, Romaya J, Wyatt JS, Delpy DT and Zeki S.
Regional changes in cerebral haemodynamics as a result of a visual stimulus measured by near infrared spectroscopy. 1995. Proc R Soc Lond B 261:351-356

Elwell CE, Matcher SJ, Tyszczuk L, Meek JH and Delpy DT.
Measurement of venous cerebral saturation in adults using near infrared spectroscopy. 1997. Adv Exp Med & Biol 411: 453-60

Meek JH, Tyszczuk LT, Elwell CE and Wyatt JS.
Cerebral blood flow increases over the first three days of life in extremely preterm neonates. 1998 Arch Dis Child 78:F33-F37

Amess PN, Baudin J, Townsend J, Meek J, Roth SC, Neville BGR, Wyatt JS, and Stewart A.
Epilepsy in very preterm infants: neonatal cranial ultrasound reveals a high risk subcategory. 1998 Dev Med Child Neurol. 40: 724-730

Tyszcsuk LT, Meek JH, Elwell C and Wyatt JS.
Cerebral blood flow is independent of mean arterial blood pressure in preterm infants undergoing intensive care. 1998  Pediatrics 102:337-341

Meek JH, Firbank M, Elwell CE, Atkinson J, Braddick O and Wyatt JS.
Regional haemodynamic responses to visual stimulation in awake infants. 1998 Ped Res (Rapid Communication) 43:840-843

Meek JH, Tyszczuk L, Elwell CE and Wyatt JS.
Low cerebral blood flow is a risk factor for severe intraventricular haemorrhage.1999 Arch Dis Child 81: F15 - F18

Meek JH, Elwell CE, McCormick DC, Edwards AD, Townsend JP, Stewart AL and Wyatt JS
Abnormal cerebral haemodynamics in perinatally asphyxiated neonates related to outcome. 1999 Arch Dis Child 81: F110 - F115

Wyatt JS, Meek J. Commentary on cerebral intravascular oxygenation correlates with mean arterial pressure in critically ill premature infants. Pediatrics 2000; 106: 828

Meek JH.
Basic principles of optical imaging, and its application to paediatrics. 2002
Developmental Science, "Imaging Techniques and their Application to
Developmental Science". 5.3: 371-380

Meek JH and Wyatt JS.
Near infrared spectroscopy in paediatrics. 2002. Book chapter in Guidebook to near infrared cerebral oxygen monitoring for clinicians. The Japan Society for the Monitoring of Cerebral Metabolism.

Vaithianathan T, Tullis IDC, Everdell N, Leung T, Meek J, Delpy DT. 2003. Functional imaging of the brain using a portable NIR instrument. Proc. of SPIE 4955: 96-102

Yusof R Md, Hebden JC, Gibson A, Everdell N, Austin T,
Meek JH, Arridge SH, Wyatt JS, and Delpy DT. 2003. Validation of the use of homogenous reference phantoms for optical tomography of the neonatal brain.
SPIE Proc. "Optical Tomography and Spectroscopy of Tissue V"  4955: 6-11.

Noone MA, Sellwood M, Meek JH and Wyatt JS. 2003. Postnatal adaptation of cerebral blood flow using near infrared spectroscoy in extremely preterm infants undergoing high-frequency oscillatory ventilation. Acta Paediatr 92: 1-7

Hebden JC, Gibson A, Austin T, Yusof R MD, Everdell N,
Delpy DT, Arridge AR, Meek JH, Wyatt JS.  2004
Imaging changes in blood volume and oxygenation in the
newborn infant brain using three-dimensional optical tomography. Physics in Medicine and Biology 49: 1117 - 1130.

Csibra G, Henty J, Volein A, Elwell C, Tucker L, Meek J, Johnson M.
Near infrared spectroscopy reveals neural activation during face perception in infants and adults. 2004 J Paed Neurology 2(2): 85-89

Vaithianathan T,  Tullis I, Everdell N, Leung T, Gibson A, Meek J, Delpy D. Design of a portable near infrared system for topographic imaging of the brain in babies.2004 Review of Scientific Instruments 75(10): 3276-3283

Elwell C.E., Henty J.H., Leung T.S., Austin T, Meek J., Delpy D.T., Wyatt J.S. 2005 Regional measurements of CMRO2 in neonates undergoing intensive care using near infrared spectroscopy. Adv. Exp. Med. & Biol. 566:263-268

Slater R, Cantarella A, Worley A, Boyd A, Meek J and Fitzgerald M. 2006 Cortical responses to noxious stimulation in preterm infants.
Proceedings of the 11th World Congress on Pain, 2006. Eds Herta Flor, Eija Kalso and Jonathan O. Dostrovsky. IASP Press
Gibson AP, Austin T, Everdell N, Schweiger M, Arridge SR, Meek JH, Wyatt JS, Delpy DT, Hebden JC. 2006. Three-dimensional whole-head optical tomography of passive motor evoked responses in the neonate. NeuroImage 30:521-528

Reynolds P, Bannerjee S, Meek J. 2005. Alcohol burns in extremely low birthweight infants: still occurring.  Arch. Dis. Child. Fetal Neonatal Ed; 90: 10

Austin T, Hebden JC, Gibson AP, Branco G, Yusof R Md, Arridge SR, Meek JH, Delpy DT, Wyatt JS. 2006. Three dimensional optical imaging of blood volume and oxygenation in the preterm brain. NeuroImage 31:1426-1433

Slater R, Cantarella A, Worley A, Boyd S, Meek J, Fitzgerald M.  2006. Cortical Responses to Noxious Stimulation in Preterm Infants. J. Neuroscience  26:3662-3666

Slater R, Fitzgerald M and Meek J. 2007 Can cortical responses following noxious stimulation inform us about pain processing in neonates? Semin Perinatol 31:298-302

Wong F, Leung T, Austin T, Wilkinson M, Meek J, Wyatt J, Walker A. 2008  Impaired autoregulation in preterm infants identified by using spatially resolved spectroscopy. Paediatrics 121; e604-e611

Colson S, Meek J, Hawdon J. 2008  Optimal positions for the release of primitive neonatal reflexes stimulating breastfeeding. Early Human Development 84:441-449

Slater R, Cantarella A, Franck L, Meek J, Fitzgerald M. 2008 How well do clinical pain assessment tools reflect pain in infants? 5:e129