Professional background

  • Degree (ptychio) in medicine, Aristotle University of Thessaloniki, Greece (2005).
  • Specialty Training Post in General Surgery (part of the obstetrics & gynaecology training programme) at the General Hospital of Florina, Greece (2007-2008).
  • Specialty training post in Gynaecology in the gynaecological oncology Department of the “Theagenio” Cancer Hospital in Thessaloniki, Greece (2009-2011).
  • Visiting research scholar, Drexel University College of Medicine, Philadelphia, PA, USA & Sbarro institute for Cancer Research and Molecular Medicine, Center for Biotechnology, Temple University, Philadelphia, PA, USA - The dynamics of the microtubule cytoskeleton in ovarian cancer. (August 2010 – September 2010).
  • Specialty training post in obstetrics & gynaecology in the obstetrics & gynaecology department (Medical School, University of Patras) at the General University Hospital of Patras, Greece (2011-2013).
  • PhD in Medicine, Medical School, Aristotle University of Thessaloniki, Greece (2015). Notch receptors in ovarian cancer.
  • Clinical research fellow in gynaecological oncology. Northern Gynaecological Oncology Centre. Queen Elizabeth Hospital. Gateshead NHS Foundation Trust. Gateshead. UK (2014-2017).
  • MPhil in gynaecological oncology, Northern Institute for Cancer Research, Medical School, Newcastle University, United Kingdom (2018). The role of PARP in the chemo-radiation response in cervical cancer.
  • RCOG/BSCCP accreditation in diagnostic and treatment colposcopy (2019).
  • RCOG subspecialty trainee in gynaecology oncology. University College London Hospital (UCLH). University College London Hospitals NHS Foundation Trust. London. United Kingdom (2017-2019).
  • Fellow in radical hysterectomy and HIPEC. 1st Gynaecological Oncology Department, Hunan Cancer Hospital, Changsha, Hunan Province, People’s Republic of China. (July 2019 – August 2019).

Research interests

Gynaecological oncology

Involvement into clinical trials & studies

  • VULCAN study: PI for Theagenio Cancer Hospital
  • STATEC: Sub-investigator for UCLH
  • 100,000 Genome Project
  • UKCOGS (phase I): PI for UCLH


Publications in International peer-review journals: 27

Author in book chapters: 2

Reviewer in peer-review journals: BJOG, Journal of Experimental & Clinical Cancer Research

Selected publications:

  • Kasivisvanathan V, Lindsay J, Rakshani-Moghadam S, Elhamshary A, Kapriniotis K, at al. & UCLH study group collaborators A cohort study of 30 day mortality after NON-EMERGENCY surgery in a COVID-19 cold site. Int J Surg. 2020 Oct 24;84:57-65.
  • Zapardiel I , Gracia M , Díez J , Buda A, Noya MC, De Iaco P, Vieira-Baptista P, Iacoponi S, & VULCAN Study Collaborative group Prognostic factors for recurrence and survival in uncommon variants of vulvar cancer. Arch Gynecol Obstet. 2020 Oct 16. 
  • Chiva L, Zanagnolo V, Querleu D, et al.; SUCCOR study Group.

SUCCOR study: an international European cohort observational study comparing minimally invasive surgery versus open abdominal radical hysterectomy in patients with stage IB1 cervical cancer Int J Gynecol Cancer 2020 Sep;30(9):1269-1277.


  • Ioannis C Kotsopoulos, Clare L Newton, Timothy A Mould. Invasive Cervical Cancer Obstet Gynaecol Reprod Med, 2020;30(6):167-174
  • Zapardiel, Ignacio; Iacoponi, Sara; Coronado, Pluvio J.; Zalewski, Kamil; Chen, Frank; Fotopoulou, Christina; Dursum, Polat; Kotsopoulos, Ioannis C.; et al. on behalf of VULCAN Study collaborative group. Prognostic factors in patients with vulvar cancer: the VULCAN study. Int J Gynecol Cancer, 2020;30(9):1285-1291
  • Kotsopoulos IC, Papanikolaou A, Papazisis KT, Hadzidimitriou A, Touplikioti P, Tsolakidis D, Lambropoulos AF, Tarlatzis BC. The differential gene expression of Notch receptors in primary and metastatic epithelial ovarian cancer sites. Eur J Gynaecol Oncol, 2019;40(1):84-90
  • Iacoponi, Sara; Rubio, Patricia; Garcia, Enrique; Oehler, Martin K.; Diez, Javier; Diaz-De la Noval, Begoña; Mora, Pablo; Gardella, Barbara; Gomez, Ivan; Kotsopoulos, Ioannis C.; Zalewski, Kamil; Zapardiel, Ignacio; on behalf of VULCAN Study collaborative group. Prognostic Factors of Recurrence and Survival in Vulvar Melanoma: Subgroup Analysis of the VULvar CANcer Study. Int J Gynecol Cancer 2016 Sep;26(7):1307-1312
  • Kotsopoulos IC, Kucukmetin A, Mukhopadhyay A, Lunec J, Curtin NJ. Poly(ADP-Ribose) Polymerase in Cervical Cancer Pathogenesis: Mechanism and Potential Role for PARP Inhibitors. Int J Gynecol Cancer. 2016 May;26(4):763-9
  • Charatsi DI, Kotsopoulos IC, Xirou P, Valeri RM, Kaplanis K. Synchronous adenocarcinoma and echinococcosis in the same ovary: a rare clinical entity. Hippokratia, 2015 Jan-Mar;19(1):88-91
  • Kotsopoulos IC, Papanikolaou A, Lambropoulos AF, Papazisis KT, Tsolakidis D, Touplikioti P, Tarlatzis BC. Serous Ovarian Cancer Signalling Pathways. Int J Gynecol Cancer 2014 Mar;24(3):410-7
  • Zygouris D, Kotsopoulos IC, Chalvatzas N, Maltaris T, Kartsiounis V, Kavallaris A. Laparoscopic para-aortic and pelvic lymphadenectomy and radical hysterectomy in a patient with cervical cancer, six months after primary chemoradiation. Eur J Gynaecol Oncol 2013;34(5):484-486
  • Kotsopoulos IC, Xirou PA, Deligiannis DA, Tsapanos VS. Coexistence of three benign and a borderline tumour on the ovaries of a 52-year-old woman. Eur J Gynaecol Oncol 2013;34(2):186-188
  • Kotsopoulos IC, Barbetakis N, Asteriou C, Voutsas MG. Uterine smooth muscle tumour of uncertain malignant potential: A rare cause of multiple pulmonary nodules. Indian J Med Paediatr Oncol. 2012 Jul;33(3):176-8
  • Kotsopoulos IC, Tsapanos VS. Patient groups that fimbriectomy could reduce high grade serous ovarian cancer incidence. Gynecol Oncol. 2013 Jan;128(1):151-2
  • Kotsopoulos IC, Tampakoudis GP, Evaggelinos DG, Nikolaidou AI, Fytili PA, Kartsiounis VC, Gerasimidou DK. Implication of human papillomavirus-66 in vulvar carcinoma: a case report. J Med Case Reports. 2011 Jun 25;5:232
  • Ioannis Kotsopoulos, Dimitrios Evaggelinos, Paraskevi Skafida, Vasilios Kartsiounis, Nektarios Chalvatzas, Andreas Kavallaris. Excessive production of ascitic fluid after laparoscopic operation for early-stage ovarian cancer. Gynecol Surg (2011) 8:85-87
  • Barbetakis N, Asteriou C, Kleontas A, Kotsopoulos I. Incarcerated maternal diaphragmatic hernia mimics hyperemesis gravidarum. A difficult differential diagnosis. Interact Cardiovasc Thorac Surg. 2010 Nov;11(5):714-5