Professional background

MA University of Cambridge

PhD University of Cambridge

MB BChir University of Cambridge

MRCP

FRCPsych

Professor Joyce trained in psychiatry at the Bethlem and Maudsley Hospitals. She spent several years as a research worker at the Institute of Psychiatry, where she was a Wellcome Trust Lecturer in Mental Health, and at the USA National Institutes of Health. Before moving to UCL/UCLH in 2005, she was Professor of Neuropsychiatry at Imperial College London. She has been Chair of The British Neuropsychiatry Association and The Faculty of Neuropsychiatry, Royal College of Psychiatrists. As well as accepting general neuropsychiatry referrals, she runs a specialist clinic for Tourette’s syndrome and provides internal neuropsychiatric opinions for patients with movement disorders such as Parkinson’s disease. She is a Trustee of Tourette’s Action.

Research interests

Psychosis, deep brain stimulation, Tourette’s syndrome, functional neurological disorder

Publications

Selected recent publications
Psychosis:

  • Barnes TR et al. Evidence-based guidelines for the pharmacological treatment of schizophrenia: Updated recommendations from the British Association for Psychopharmacology. J Psychopharmacol. 2020. 34(1):3-78.
  • Lennox B et al. Intravenous immunoglobulin and rituximab versus placebo treatment of antibody-associated psychosis: study protocol of a randomised phase IIa double-blinded placebo-controlled trial (SINAPPS2). Trials. 2019 Jun 7;20(1):331.
  • Deakin B at al. The benefit of minocycline on negative symptoms of schizophrenia in patients with recent-onset psychosis (BeneMin): a randomised, double-blind, placebo-controlled trial. Lancet Psychiatry. 2018. 5(11):885-894.
  • Wykes T, Joyce E et al. The CIRCuiTS study (Implementation of cognitive remediation in early intervention services): protocol for a randomised controlled trial. Trials. 2018 Mar 15;19(1):183.

Deep Brain Stimulation:

  • Li N et al. A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder Nature Communications. 2020. 11:3364; https://doi.org/10.1038/s41467-020-16734-3.
  • Tyagi H et al. A Randomized Trial Directly Comparing Ventral Capsule and Anteromedial Subthalamic Nucleus Stimulation in Obsessive-Compulsive Disorder: Clinical and Imaging Evidence for Dissociable Effects. Biol Psychiatry. 2019, 85(9):726-734
  • Johnson KA et al. Image-based analysis and long-term clinical outcomes of deep brain stimulation for Tourette syndrome: a multisite study. J Neurol Neurosurg Psychiatry. 2019 Oct;90(10):1078-1090.
  • Martinez-Ramirez D et al. Efficacy and Safety of Deep Brain Stimulation in Tourette Syndrome: The International Tourette Syndrome Deep Brain Stimulation Public Database and Registry. JAMA Neurol. 2018.75(3):353-359

Tourette’s syndrome:

  • Rawji V et al. Impaired automatic but intact volitional inhibition in primary tic disorders. Brain. 2020 Mar 1;143(3):906-919.
  • Zapparoli L et al., Voluntary tic suppression and the normalization of motor cortical beta power in Gilles de la Tourette syndrome: an EEG study. Eur J Neurosci. 2019 Dec;50(12):3944-3957.
  • Ganos C et al. Motor cortical excitability during voluntary inhibition of involuntary tic movements. Mov Disord. 2018 Nov;33(11):1804-1809.

Functional neurological disorder:

  • Pick et al. Outcome measurement in functional neurological disorder: a systematic review and recommendations. J Neurol Neurosurg Psychiatry. 2020. 91(6):638-649.
  • Nielsen G et al. Randomised feasibility study of physiotherapy for patients with functional motor symptoms.J Neurol Neurosurg Psychiatry. 2017 Jun;88(6):484-490.