Professional background

MBChB, University of Dundee 1991.

My initial training was in general adult medicine gaining membership of the Royal College of Physicians in 1995. I spent two and a half years as clinical fellow in bone marrow transplantation at the Royal Hospital for Sick Children in Bristol, where I also undertook a period of research in minimal residual disease in acute lymphoblastic leukaemia.

My general haematology training (MRCPath 2005, FRCPath 2008) was predominantly gained at UCLH and Great Ormond Street Hospital and included a further period of training in bone marrow transplantation. During this time I undertook a period of research (2001-2004) gaining a PhD in signal transduction in acute myeloid leukaemia (2001).

My training in paediatric and adult haematology led me to develop an interest in adolescent haematology, and I was appointed as consultant haematologist for the children and young people’s cancer service at UCLH in April 2007.

Research interests

Acute myeloid leukaemia, non-malignant haematology, bone marrow transplantation, late effects of cancer treatment


  • Fertility Among Female Survivors of Childhood, Adolescent, and Young Adult Cancer: Protocol for Two Pan-European Studies (PanCareLIFE). van den Berg M, van Dijk M, Byrne J, Campbell H, Berger C, Borgmann-Staudt A, Calaminus G, Dirksen U, Winther JF, Fossa SD, Grabow D, Grandage VL, van den Heuvel-Eibrink MM, Kaiser M, Kepak T, Kremer LC, Kruseova J, Kuehni CE, Lambalk CB, van Leeuwen FE, Leiper A, Modan-Moses D, Morsellino V, Spix C, Kaatsch P, van Dulmen-den Broeder E; PanCareLIFE Consortium. JMIR Res Protoc. 2018 Sep 14;7(9):e10824. doi: 10.2196/10824. PMID: 30215599 Free PMC article.
  • PanCareLIFE: The scientific basis for a European project to improve long-term care regarding fertility, ototoxicity and health-related quality of life after cancer occurring among children and adolescents. Byrne J, Grabow D, Campbell H, O'Brien K, Bielack S, Am Zehnhoff-Dinnesen A, Calaminus G, Kremer L, Langer T, van den Heuvel-Eibrink MM, van Dulmen-den Broeder E, Baust K, Bautz A, Beck JD, Berger C, Binder H, Borgmann-Staudt A, Broer L, Cario H, Casagranda L, Clemens E, Deuster D, de Vries A, Dirksen U, Winther JF, Fosså S, Font-Gonzalez A, Grandage V, Haupt R, Hecker-Nolting S, Hjorth L, Kaiser M, Kenborg L, Kepak T, Kepáková K, Knudsen LE, Krawczuk-Rybak M, Kruseova J, Kuehni CE, Kunstreich M, Kuonen R, Lackner H, Leiper A, Loeffen EAH, Luks A, Modan-Moses D, Mulder R, Parfitt R, Paul NW, Ranft A, Ruud E, Schilling R, Spix C, Stefanowicz J, Strau? G, Uitterlinden AG, van den Berg M, van der Kooi AL, van Dijk M, van Leeuwen F, Zolk O, Zöller D, Kaatsch P; PanCareLIFE consortium. Eur J Cancer. 2018 Nov;103:227-237. doi: 10.1016/j.ejca.2018.08.007. Epub 2018 Sep 29. PMID: 30273888
  • Genetic variation in gonadal impairment in female survivors of childhood cancer: a PanCareLIFE study protocol. van der Kooi ALF, Clemens E, Broer L, Zolk O, Byrne J, Campbell H, van den Berg M, Berger C, Calaminus G, Dirksen U, Winther JF, Fosså SD, Grabow D, Haupt R, Kaiser M, Kepak T, Kremer L, Kruseova J, Modan-Moses D, Ranft A, Spix C, Kaatsch P, Laven JSE, van Dulmen-den Broeder E, Uitterlinden AG, van den Heuvel-Eibrink MM; PanCareLIFE Consortium. BMC Cancer. 2018 Sep 26;18(1):930. doi: 10.1186/s12885-018-4834-3. PMID: 30257669 Free PMC article. Clinical Trial.
  • Rapid clinical response to adjuvant corticosteroids in chronic disseminated candidiasis complicated by granulomas and persistent fever in acute leukemia patients. Fox TA, Halsey R, Pomplun S, Gant V, Grandage V, Mansour MR, Hough R, Khwaja A. Leuk Lymphoma. 2020 Apr;61(4):944-949. doi: 10.1080/10428194.2019.1691198. Epub 2019 Nov 22. PMID: 31755343 No abstract available.
  • Intensive Chemotherapy Is Associated With Poor Overall Survival in Autoimmune Disease-associated Myeloid Malignancies. Richardson SE, Brian D, Grandage V, Hough R, Kottaridis P, Mansour MR, Payne EM, Khwaja A. Hemasphere. 2018 Dec 21;3(1):e164. doi: 10.1097/HS9.0000000000000164. eCollection 2019 Feb. PMID: 31723803 Free PMC article. No abstract available.
  • The incidence of invasive fungal infections in children, adolescents and young adults with acute lymphoblastic leukaemia/lymphoma treated with the UKALL2011 protocol: a multicentre retrospective study. O'Reilly MA, Govender D, Kirkwood AA, Vora A, Samarasinghe S, Khwaja A, Grandage V, Rao A, Ancliff P, Pavasovic V, Cheng D, Carpenter B, Daw S, Hough R, O'Connor D. Br J Haematol. 2019 Jul;186(2):327-329. doi: 10.1111/bjh.15798. Epub 2019 Feb 15. PMID: 30768682 Clinical Trial. No abstract available.
  • Successful outcome following allogeneic hematopoietic stem cell transplantation in adults with primary immunodeficiency. Fox TA, Chakraverty R, Burns S, Carpenter B, Thomson K, Lowe D, Fielding A, Peggs K, Kottaridis P, Uttenthal B, Bigley V, Buckland M, Grandage V, Denovan S, Grace S, Dahlstrom J, Workman S, Symes A, Mackinnon S, Hough R, Morris E. Blood. 2018 Feb 22;131(8):917-931. doi: 10.1182/blood-2017-09-807487. Epub 2017 Dec 26. PMID: 29279357 Free PMC article.
  • Late onset cytopenias following haematopoietic stem cell transplant associated with viral infection and cell specific antibodies. Lucas G, Culliford S, Bendukidze N, Dahlstrom J, Grandage V, Carpenter B, Hough R. Transpl Immunol. 2017 Mar;41:32-36. doi: 10.1016/j.trim.2017.02.002. Epub 2017 Feb 4. PMID: 28167271