Ed Seward trained in Edinburgh for six years before moving first to Liverpool and then London, where he worked as a registrar and gained his MD. His first consultant’s post was at Whipps Cross Hospital – now part of Barts Health NHS Trust. Situated in the diverse area of Waltham Forest, this enabled him to develop a broad experience in Gastroenterology.
As Endoscopy Lead he developed a sub-specialist interest in therapeutic endoscopy with particular expertise in colonoscopy and colonic stenting, and ERCP. It also allowed him to pursue a passion for service improvement and redesign, which culminated in his appointment as a National Clinical Advisor for Endoscopy. More recently, he has been responsible for piloting a pathway to shorten diagnostic waits in colorectal cancer which was shortlisted for a prestigious BMJ award, has now been adopted nationally through Cancer Research UK’s ACE programme.
Ed was appointed to UCLH in 2014 to deliver ‘Bowel Scope’ for the North central area of London – the national plan to provide screening for bowel cancer and polyps to all 55 year olds. He is also tasked with helping to deliver an interventional colonoscopy service, and to improve the colonoscopy teaching and research brief at UCLH. Alongside this, he also works as a ‘Vanguard’ early diagnosis lead for colorectal cancer and is involved in a critical piece of research to introduce Faecal Immunochemical Testing (FIT) to primary care across North London and Essex to optimise the pathway for people with bowel symptoms. He was appointed Director of Endoscopy at UCLH in 2019 and contributes towards research into use of Artificial Intelligence in endoscopy.
MD in the pathogenesis of pancreatitis and clinical studies on biliary dyskinesia.
Shortening diagnostic pathways for colorectal cancer.
Service redesign in Endoscopy.
Use of Artificial Intelligence for polyp detection in the colon.
Seward E. Medicine and Malaria in Rural India. Proceedings of the Royal College of Physicians of Edinburgh 1996; 26: 500-501 Seward EW, Rustom R, Nye FJ, Bone JM. Haemolytic-uraemic syndrome following human parvovirus infection in a previously fit adult Nephrology, Dialysis and Transplantation 1999; 14 (10): 2472-3
Seward E, Greig E, Preston S, Harris RA, Borrill Z, Wardle TD, Burnham R, Driscoll P, Harrison BDW, Lowe D, Pearson MG. A Confidential Study of Deaths after Emergency Medical Admission: Issues Relating to Quality of Care. Clinical Medicine 2003;3: 425-34
Deheragoda MG, Church NI, Rodriguez-Justo M, Munson P, Sandanayake N, Seward EW, Miller K, Novelli M, Hatfield AR, Pereira SP, Webster GJ.The use of immunoglobulin g4 immunostaining in diagnosing pancreatic and extrapancreatic involvement in autoimmune pancreatitis. Clin Gastroenterol Hepatol. 2007 Oct;5(10):1229-34.
Church NI, Pereira SP, Deheragoda MG, Sandanayake N, Amin Z, Lees WR, Gillams A, Rodriguez-Justo M, Novelli M, Seward EW, Hatfield AR, Webster GJ Autoimmune pancreatitis: clinical and radiological features and objective response to steroid therapy in a UK series Am J Gastroenterol. 2007 Nov;102(11):2417-25.
Makins R, Seward E Small bowel cancer: should relatives be screened for Lynch syndrome? 2008 Gut 57(1): 140 Jawad N, Bhagat T, Murray S, Jawad F, Makins RJ, Seward EW. Do endoscopy audit tools overestimate polyp detection rates? Gut 2008; 57 A97
Paranandi B, Anglim N, Sawyerr A, Carty E, Seward E. Caecal intubation with a gastroscope following an incomplete colonoscopy - is it feasible? Gut 2009; 58 A53
Anglim NS, Seward EW, Sawyerr AM, Carty E Can colonoscopists size colonic polyps accurately and does it matter? Gut 2009; 58 A89
Murray S, Nizamuddin M, Raj A, Seward E. Gatrointestinal cancer: an opportunity missed Gut 2009; 58 A133
Siaw YH, Joshi N, Selveraj E, Steward L, Greaves R, Watson A, Hoque S, Seward E Providing a colonic stenting service for malignant bowel obstruction: a district general hospital experience Gut 2012; 61(suppl 2) A294
Macdonald S, Radhakrishnan S, Seward E Is flexible sigmoidoscopy ever enough? An audit of rates of proximal disease during colonoscopy. Gut 2013; A34
Tai FWD, Selveraj E, Siaw YH, Seward E Risk stratification of upper gastrointestinal bleeding with the Glasgow-Blatchford score: experience of a district general hospital in East London, United Kingdom Gut 2013; A78
Andrews P, Watson H, Mistry M, Machesney M, Seward E Straight to test colonoscopy - a viable means of shortening time to a definitive diagnosis Gut 2014; 63 (suppl 1) A27
Wadsworth CA, Dwyer LK, Paranandi B, Philips N, Mahmood S, Krishnan B, Taylor TL, Seward E, Wilson P, Singhal A, Williams E, Westaby D, Webster GJ, Sturgess RP Current performance of ERCP in the clearance of bile duct stones in UK centres - working towards robust key performance indicators Gut 2014; 63 (suppl 1) A210
Chung D, Matoo K, Seward E et al. The First UK Multidisciplinary Diagnostic Centre: A Novel Cancer Diagnostic Service Gut 2016;65(1):A1–A310
Samaan MA, Seward E et al. Current Practices in Ileal Pouch Surveillance for Ulcerative Colitis Patients in Three London IBD Referral Centres Gastroenterology 2017 Volume 152, Issue 5, S377
Fawkes, J; Corpus, M; Seward E et al. Colonoscopy versus CTC in the North Central London bowel cancer screening programme. Gut 2017 Supp 2;66
Seward E, Lumley S. Endoscopy provision: meeting the challenges Frontline Gastroenterology 2017;8:90–93.
Alexander J, Johnston B, Seward E, et al. OWE-25 Patients with multiple adenomas in bowel cancer screening program are not referred for genetic testing. Gut 2019;68:A188.
Samaan MA, Seward E et al. Current Practices in Ileal Pouch Surveillance for Patients With Ulcerative Colitis: A Multinational, Retrospective Cohort Study, Journal of Crohn's and Colitis, Volume 13, Issue 6, June 2019, Pages 735–743
Calderbank T, Black G, Theaker H, Seward E et al. PTH-008 Endoscopy reporting in ulcerative colitis: identifying areas of suboptimal practice to define an intervention bundle. Gut 2019;68:A17-A18.
Gadhok R, Rao R, Honap S, Seward E et al. PTH-084 Ustekinumab: Early experience and medium-term outcomes from a UK multi-centre real-world cohort. Gut 2019;68:A74-A75.
Fawkes J, Seward E In-house training for clinical endoscopists:
a personal account Gastrointestinal Nursing 2019; 17(1) S24
Sehgal V, Yearwood A, Chaudhry M, Seward E et al. OTH-01 A complex lower gastrointestinal polyp MDT improves evidence-based decision making and efficiency of endoscopy scheduling. Gut 2019;68:A220-A221
Seward E Recent Advances In Colonoscopy F1000Res. 2019; 8: F1000 Faculty Rev-1028.
Ahmad FA, Soares AS, Mazomenos E, Seward E et al Artificial intelligence and computer-aided diagnosis in colonoscopy: current evidence and future directions Lancet Gastroenterol Hepatol 2019; 4: 71–80