Professional background

Farooq Rahman is a consultant gastroenterologist at University College Hospital and honorary associate professor at University College London.

He studied medicine at The Royal Free Hospital School of Medicine in London and completed his specialist training on the North East London rotation. He obtained his PhD from UCL studying the immunopathogenesis of inflammatory bowel disease.

He is a luminal gastroenterologist with subspecialty interests in inflammatory bowel disease, clinical nutrition & intestinal failure and radiation enteropathy. He also maintains a busy clinical practice and has extensive experience in general gastroenterology and colonoscopy. He maintains a strong commitment to undergraduate/postgraduate teaching and training and training and remains actively involved in clinical and translational research.

Research interests

  • Inflammatory bowel disease: immunopathogenesis
  • Intestinal failure
  • Clinical nutrition
  • Radiation enteropathy


S DiCaro, K Fragkos, K Keetarut, HF Khoo, G Sebebos-Rogers, H Saravanapavan, J Barragry, J Rogers, S Mehta, F Rahman. Enteral nutrition in adult Crohn’s disease: toward a paradigm shift. 2019

S Burden, D Jones, M Gittins, J Ablett, M Taylor, C Moutford, J Tyrell-Price, C Donellan, F Leslie, T Bowling, S Gabe, F Rahman et al. Needs-based quality of life in adults dependent on HPN. Clin Nutr. 2019

K Fragkos, S DiCaro, S Mehta, F Rahman. Response to letter re: Refeeding syndrome in adults receiving total parenteral nutrition: An audit of practice at a tertiary UK centre. Clin Nutr. 2019: 38(2): 968

MA Samaan, K Forsyth, JP Segal, D de Jong, J Vleugels, S Elkady, M Kabir, S Campbell, K Kok, DG Armstrong, L Penez, AP Arenaza, E Seward, R Vega, S Mehta, F Rahman et al. Current Practices in Ileal Pouch Surveillance for Patients with UC: A Multinational, Retrospective Cohort Study. JCC. 2018

T Kumagai, F Rahman, A Smith. The microbiome and radiation-induced bowel injury: evidence for potential mechanistic role in disease pathogenesis. Nutrients 2018 Oct 2;10(10)A Miles & METRIC investigators. MRE, small bowel ultrasound and colonoscopy to diagnose and stage Crohn’s disease: patient acceptability and perceived burden. Eur Radiol. 2019:;29(3):1083-1093

Y Wouters, M Theilla, P Singer, S Tribler, P Jeppesen, L Pironi, L Vinter-Jensen, H Rasmussen, F Rahman, G Wanten. RCT of 2% taurolidine versus 0.9% saline locking in patients on HPN. 2018; 48(4): 410-422

F Pantoja, K Fragkos, P Patel, N Keane, M Samaan, I Barnova, S DiCaro, S Mehta, F Rahman. Refeeding syndrome in adults receiving total parenteral nutrition: An audit of practice at a tertiary UK centre. Clin Nutr. 2019; 38(3): 457–1463

SA Taylor & METRIC study investigators. Diagnostic accuracy of magnetic resonance enterography and small bowel ultrasound for the extent and activity of newly diagnosed and relapsed Crohn’s disease (METRIC): a multicentre trial. Lancet Gastroenterol Hepatol. 2018; 3(8): 548-558

N Keane, K Fragkos, P Patel, F Bertsch, S Mehta, S Di Caro, F Rahman. Performance status, prognostic scoring and PN requirements predict survival in patients with advanced cancer receiving HPN. Nutr Cancer. 2018; 70(1): 73-82

MA Samaan, D de Jong, S Sahami, S Morgan, K Fragkos, S Subramaniam, K Kok, J Makanyanga, I Barnova, H Saravanapavan, I Parisi, S Di Caro, R Vega, FZ Rahman, et al. Incidence and severity of pre-pouch ileitis: A distinct disease entity or a manifestation of refractory pouchitis. Inflamm Bowel Dis. 2016; 22(3): 662-8

Y Chen, M Ogundare, CM Williams, Y Wang, GW Sewell, PJ Smith, FZ Rahman, et al. Shotgun cholanomics of ileal fluid. Biochimie. 2013; 95(3): 461-3G

W Sewell, YA Hannun, X Han, G Koster, J Bielawski, V Goss, PJ Smith, FZ Rahman, et al. Lipidomic profiling in Crohn’s disease: abnormalities in phosphatidylinositols, with preservation of ceramide, phosphatidylcholine and phosphatidylserine composition. Int J Biochem Cell Biol. 2012; 44(11): 1839-46

FZ Rahman, GW Sewell, et al. Defective TNF release from Crohn’s disease macrophages in response to Toll-like receptor activation: relationship to phenotype and genome wide association susceptibility loci. Inflamm Bowel Dis. 2012; 18(11): 2120-7

B Hayee, A Antonopoulos, EJ Murphy, FZ Rahman, et al. G6PC3 mutations are associated with a major defect of glycosylation: a novel mechanism for neutrophil dysfunction. Glycobiology. 2011; 21(7): 914-924DJB Marks, PJ Smith, FZ Rahman, et al. Cryptogenic colitis due to occult cytomegalovirus infection. Frontline Gastroenterol. 2011; 2: 57-62

S Ghosh, FZ Rahman, et al. Survival following treatment of aorto-esophageal fistula with dual esophageal and aortic intervention. Case Reports in Gastroenterol. 2011; 5(1): 40-44

B Hayee, FZ Rahman, et al. The neutrophil respiratory burst and bacterial digestion in Crohn's disease. Dig Dis Sci. 2011; 56(5): 1482-1488FZ Rahman, et al. Henoch Schönlein Purpura complicating adalimumab therapy for Crohn’s disease. World J Gastrointest Pharmacol Ther. 2010; 1(5): 119-122

DJB Marks, CR Seymour, GW Sewell, FZ Rahman, et al. Do adaptive or complement immunodeficiencies predispose to inflammatory bowel disease? A critical review. Inflamm Bowel Dis. 2010; 16(11): 1984-1992B Hayee, FZ Rahman, et al. Perspective article: Crohn’s Disease as an Immunodeficiency. Expert Review of Clinical Immunology 2010; 6(4): 585-596

FZ Rahman, AM Smith, et al. Delayed resolution of acute inflammation in ulcerative colitis is associated with elevated cytokine release downstream of TLR4. PLoS One 2010; 5(3): e9891DJB Marks, FZ Rahman, GW Sewell, AW Segal. Crohn’s disease: an immune deficiency state. Crit Rev Allergy Immunol. 2010; 38(1): 20-31

CD Palmer, FZ Rahman, et al. Multiple PMA-induced macrophage PKC signalling abnormalities in Crohn’s disease. PLoS One 2009; 4(11): e7787

FZ Rahman, et al. Impaired macrophage function following bacterial stimulation in chronic granulomatous disease. Immunology 2009; 128(2): 253-259FZ Rahman, AM Smith, et al. Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn’s disease. J Exp Med. 2009; 206(9): 1883-1897

R Rajkariar, J. Newson, EK Jackson, P Sawmynaden, A Smith, FZ Rahman, MM Yaqoob, DW Gilroy. Non-resolving inflammation in gp91phox-/- mice, a model for human Chronic Granulomatous Disease, is associated with lower adenosine and cAMP levels. J Immunol. 2009; 182(5): 3262-3269

DJB Marks, K Miyagi, FZ Rahman, et al. Inflammatory bowel disease in CGD reproduces the clinicopathological features of Crohn’s disease. Am J Gastroenterol. 2009; 104(1): 117-124FZ Rahman, DJB Marks, et al. Phagocyte dysfunction and Inflammatory bowel disease. Inflamm Bowel Dis. 2008; 14(10): 1443-1452

DJ Marks, FZ Rahman, et al. An exuberant inflammatory response to E.coli: implications for the pathogenesis of ulcerative colitis and pyoderma gangrenosum. Gut 2006; 55(11): 1662-1663DJ Marks, M Harbord, R MacAllister, FZ Rahman, et al. Defective acute inflammation in Crohn's disease: a clinical investigation. Lancet 2006; 367(9511): 668-678