Photo of Dr Shah Islam

Dr Shah Islam

Telephone:

Email:

Location:

  • National Hospital for Neurology and Neurosurgery

GMC/GDC number:

7084947

Professional background

Dr Shah Islam graduated in 2010 from Barts and The London School of Medicine with Distinction.  He immediately entered combined clinical academic training, followed by being awarded an NIHR clinical academic fellowship in Radiology between St. Georges Hospital, London and The Institute of Cancer Research.  Following completion of his FRCR in 2016, he undertook formal research in advanced brain tumour imaging under Prof. Adam Waldman and Prof. Eric Aboagye at Imperial College London.  He led a number of clinical trials including the multicentre ‘Diffusion in Glioma’ study’ and the first in brain tumour studies using a novel PET tracer (18F- FPIA).

His interventional neuroradiology training in adult and paediatric neurointervention was exclusively between London, UK (Queen Square and Great Ormond Street for Children) and Toronto, Canada (Toronto Western Hospital and The Hospital for Sick Children, 'SickKids'). In Toronto he was trained by Prof. Pascal Mosimann, and Dr Prakash Muthusami with a focus on endovascular cerebral AVM treatments using both trans-arterial and trans-venous approaches.  He has also trained extensively in image guided spine interventions e.g. Vertebroplasty, Kyphoplasty and Radiofrequency nerve ablations under the mentorship of Prof Kieran Murphy (Toronto Western Hospital).

He has a strong commitment to delivering high quality teaching through innovation having worked closely with engineers to fabricate 3D printed models of neurovascular lesions, enabling trainees to practise skills in a simulated environment.  In addition, he is the co-founder of the Queen Square Interventional Neuroradiology Symposium, a non-profit educational platform delivered by an international faculty of key opinion leaders with a goal to improve patient outcomes through knowledge dissemination. Furthermore he has recently been elected as President of the UK largest radiology and oncology multidisciplinary congress and exhibition, UKIO.

Specialties

Research interests

  • Development of imaging biomarkers for brain tumours using computation imaging techniques.  
  • Treatment of high and low CSF pressure disorders using endovascular techniques. 

Publications

Original Research Articles

 Islam S, Inglese M, Aravind P, Barwick TD, Mauri F, McLeavy L, Årstad E, Wang J, Puccio I, Hung L, Lu H, O'Neill K, Waldman AD, Williams M, Aboagye EO. A hybrid [18F]fluoropivalate PET-multiparametric MRI to detect and characterise brain tumour metastases based on a permissive environment for monocarboxylate transport. Eur J Nucl Med Mol Imaging. 2025 Feb 7. doi: 10.1007/s00259-025-07118-0. Epub ahead of print. PMID: 39915301.
 
Nasralla M, Islam S, Vucevic D, Murphy K. Novel use of fractal analysis for quantifying polymethylmethacrylate distribution patterns in osteoporotic and malignant vertebral compression fractures following vertebroplasty, Accepted for publication in Canadian Association of Radiologists Journal, May 2024         
Islam S et al. Feasibility of [18F]fluoropivalate hybrid PET/MRI for imaging lower and higher grade glioma: a prospective first-in-patient pilot study. Eur J Nucl Med Mol Imaging. 2023 Jul 25. doi: 10.1007/s00259-023-06330-0. Epub ahead of print. PMID: 37490079.

Starup-Hansen J, Williams SC, Funnell JP, Hanrahan JG, Islam S, Al-Mohammad A, Hill CS. Optimising trajectory planning for stereotactic brain tumour biopsy using artificial intelligence: a systematic review of the literature. Br J Neurosurg. 2023 May 13:1-10. doi: 10.1080/02688697.2023.2210225. Epub ahead of print. PMID: 37177983.

Islam S, Kanavati F, Arain Z, Da Costa OF, Crum W, Aboagye EO, Rockall AG. Fully automated deep-learning section-based muscle segmentation from CT images for sarcopenia assessment. Clin Radiol. 2022 May;77(5):e363-e371. doi: 10.1016/j.crad.2022.01.036. Epub 2022 Mar 5. PMID: 35260232.

Kelly BS, Judge C, Bollard SM, Clifford SM, Healy GM, Aziz A, Mathur P, Islam S, Yeom KW, Lawlor A, Killeen RP. Radiology artificial intelligence: a systematic review and evaluation of methods (RAISE). Eur Radiol. 2022 Nov;32(11):7998-8007. doi: 10.1007/s00330-022-08784-6. Epub 2022 Apr 14. Erratum in: Eur Radiol. 2022 May 20; PMID: 35420305; PMCID: PMC9668941.                 
                                                                                                                                                    
Papastenafou V, Islam S, Szyszko T, Cohen V. Metabolic activity of primary uveal melanoma on PET/CT scan and its relationship with Monosomy 3 and other prognostic factors. British Journal of Ophthalmology. 2014 Dec;98(12):1659-65
                                                                                                                                                                      
Fellous TG, Islam S, Tadrous PJ, Elia G, Kocher HM, Bhattacharya S, Mears L, Turnbull DM, Taylor RW, Greaves LC, Chinnery PF, Taylor G, McDonald SA, Wright NA, Alison MR. Locating the Stem Cell Niche and Tracing Hepatocyte Lineages in Human Liver. Hepatology 2009; 49(5):1655-63.                                                                                                                                    
Fellous TG, McDonald SA, Burket J, Humphries A, Islam S, De-Alwis N, Gutierrez L, Tadrous, PJ, Elia, G, Kocher HM, Battacharya S, Mears L, El-Baharwy, Turnbull DM, Taylor RW, Greaves LC, Chinnery PF, Taylor G, Day C, Wright NA, Alison MR. A methodological approach to tracing cell lineage in human epithelial tissues. Stem Cells 2009; Jun; 27(6):1410-20.

Review 

Islam S, Parra-Farinas C, Muthusami P, Shroff M. Image-guided Access to the Spinal Subarachnoid Space in Children. Neuroimaging Clin N Am. 2025 Feb;35(1):155-165. doi: 10.1016/j.nic.2024.08.007. Epub 2024 Sep 23. PMID: 39521524.                                          

Islam S. Commentary on: diagnostic accuracy of a decision-support software for the detection of intracranial large vessel occlusion in CT angiography. Clin Radiol. 2023 Apr;78(4):e311-e312. doi: 10.1016/j.crad.2022.12.012. Epub 2023 Jan 12. PMID: 36710121.                                                              

Alison MR, Islam S, Wright NA. Stem cells in cancer: instigators and propagators? Journal of Cell Science 2010 Jul 15;123(Pt 14):2357-68.                                                                                                                                        

Alison MR, Islam S. Stem cells and lung cancer: future therapeutic targets? Expert Opinion in Biological Therapy 2009 Sep;9(9):1127-41.                                                                              

Alison MR, Islam S, Lim S. Cell Therapy for Liver Disease. Current Opinion in Molecular Therapeutics 2009; Jan;217(2):282-98.
                                                                                    
Alison MR, Islam S, Lim S. Number Crunching in the Cancer Stem Cells Market. Breast Cancer Research 2009;11:302.

Alison MR, Islam S. Attributes of adult stem cells. Journal of Pathology 2009; 217: 144–160.
                                                                                                                                    
Alison MR, Islam S, Lim S. Stem cells in liver regeneration, fibrosis and cancer: the good, 
the bad and the ugly. Journal of Pathology 2009; 217(2):282-98.

Book Chapters

Islam S, Robertson F. Treatment of paediatric cerebral aneurysms. Accepted for publication in Oxford Handbook of Interventional Neuroradiology. (1st Edition) Oxford University Press. 2025.
                        
Islam S, Robertson F. Paediatric cerebral angiography. (1st Edition) Accepted for publication in Oxford Handbook of Interventional Neuroradiology. (1st Edition) Oxford University Press. 2025.
            
Islam S, Qureshi. Inferior Petrosal Sinus Sampling. Accepted for publication in Oxford Handbook of Interventional Neuroradiology. (1st Edition) Oxford University Press. 2025.
                        
Islam S, Morrison M, Waldman AD. Quantitative and Physiological Magnetic resonance imaging in glioma. Functional Neuroradiology (2nd Edition) Springer May 2023

Islam S and Riddell AM. PET/CT in Oesophageal Cancer, In Pocket Guide to Science & practice of PET/CT Imaging. Elsevier 2015.
                                                                                                                                                                            
Alison MR and Islam S. (2013) Liver regeneration in health and disease. In 'Stem Cells Handbook', 2nd edition. Sell S (editor), Springer.
                                                                                                                                                                                    
Alison MR, Islam S. (2011). Stem cells of the human liver: basic science and clinical applications. In: Bongso, A and Lee, EH Stem Cells: From Bench to Bedside . 2nd ed. Singapore: World Scientific Publisher. 409-425.
                        
Lebrenne AC, Islam S, Alison MR. (2009). Stem cells and lung cancer. In: Polak J CELL THERAPY FOR LUNG DISEASE. London: Imperial College Press. 34-35.