Professional background

Huw Morris is consultant neurologist and professor of clinical neuroscience at the Royal Free Hospital, National Hospital for Neurology and Neurosurgery and UCL Institute of Neurology.

His main clinical and research interests are in movement disorders and neurogenetics, particularly early onset, genetic and familial Parkinson's disease and atypical Parkinsonian disorders such as progressive supranuclear palsy, cortico-basal degneration and fronto-temporal dementia with Parkinsonism.

His clinical and research training took place at the National Hospital, Queen Square, the Mayo Clinic and the Western Pacific island of Guam. He sees patients on an NHS and research basis. His research is funded by Parkinson's UK, the Medical Research Council, the PSP Association and the Motor Neuron Disease Association.

Research interests

  • Neurogenetics
  • Familial and genetic movement disorders
  • Early onset Parkinson’s
  • Progressive supranuclear palsy (PSP)/corticobasal syndrome (CBS)

Publications

Herbst, S., Campbell, P., Harvey, J., Bernard, E. M., Papayannopoulos, V., Wood, N. W., Morris, H. R., & Gutierrez, M. G. (2020). LRRK2 activation controls the repair of damaged endomembranes in macrophages. The EMBO Journal, e104494.

Schapira, A. H. V., & Morris, H. R. (2020). Pathogenetic insights into young-onset Parkinson disease. Nature Reviews. Neurology, 16(5), 245–246.

Jabbari, E., Holland, N., Chelban, V., Jones, P. S., Lamb, R., Rawlinson, C., Guo, T., Costantini, A. A., Tan, M. M. X., Heslegrave, A. J., Roncaroli, F., Klein, J. C., Ansorge, O., Allinson, K. S. J., Jaunmuktane, Z., Holton, J. L., Revesz, T., Warner, T. T., Lees, A. J., … Morris, H. R. (2020). Diagnosis Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Syndrome. JAMA Neurology, 77(3), 377–387.

Schapira, A. H. V., & Morris, H. R. (2020). Pathogenetic insights into young-onset Parkinson disease. Nature Reviews. Neurology, 16(5), 245–246.
Blauwendraat, C., Reed, X., Krohn, L., Heilbron, K., Bandres-Ciga, S., Tan, M., Gibbs, J. R., Hernandez, D. G., Kumaran, R., Langston, R., Bonet-Ponce, L., Alcalay, R. N., Hassin-Baer, S., Greenbaum, L., Iwaki, H., Leonard, H. L., Grenn, F. P., Ruskey, J. A., Sabir, M., … Singleton, A. B. (2020). Genetic modifiers of risk and age at onset in GBA associated Parkinson’s disease and Lewy body dementia. Brain: A Journal of Neurology, 143(1), 234–248.

Jabbari, E., Tan, M. M. X., Reynolds, R. H., Mok, K. Y., Ferrari, R., Murphy, D. P., Valentino, R. R., Ross, O. A., Dickson, D. W., Al-Sarraj, S., Gentleman, S. M., Allinson, K. S. J., Jaunmuktane, Z., Holton, J. L., Revesz, T., Warner, T. T., Lees, A. J., Cookson, M. R., Raphael Gibbs, J., … Morris, H. R. (2020). Common variation at the LRRK2 locus is associated with survival in the primary tauopathy progressive supranuclear palsy. In bioRxiv (p. 2020.02.04.932335). https://doi.org/10.1101/2020.02.04.932335

Jabbari, E., Woodside, J., Tan, M. M. X., Pavese, N., Bandmann, O., Ghosh, B. C. P., Massey, L. A., Capps, E., Warner, T. T., Lees, A. J., Revesz, T., Holton, J. L., Williams, N. M., Grosset, D. G., & Morris, H. R. (2019). The genetic and clinico-pathological profile of early-onset progressive supranuclear palsy. Movement Disorders: Official Journal of the Movement Disorder Society, 34(9), 1307–1314.

Jabbari, E., Woodside, J., Tan, M. M. X., Shoai, M., Pittman, A., Ferrari, R., Mok, K. Y., Zhang, D., Reynolds, R. H., de Silva, R., Grimm, M.-J., Respondek, G., Müller, U., Al-Sarraj, S., Gentleman, S. M., Lees, A. J., Warner, T. T., Hardy, J., Revesz, T., … Morris, H. R. (2018). Variation at the TRIM11 locus modifies progressive supranuclear palsy phenotype. Annals of Neurology, 84(4), 485–496.

Malek, N., Weil, R. S., Bresner, C., Lawton, M. A., Grosset, K. A., Tan, M., Bajaj, N., Barker, R. A., Burn, D. J., Foltynie, T., Hardy, J., Wood, N. W., Ben-Shlomo, Y., Williams, N., Grosset, D. G., & Morris, H. R. (2018). Features of GBA-associated Parkinson’s disease at presentation in the UK Tracking Parkinson's study. Journal of Neurology, Neurosurgery, and Psychiatry, 89(7), 702–709.

Revesz, T., Holton, J. L., & Morris, H. R. (2019). A novel TBK1 mutation in a family with diverse frontotemporal dementia spectrum disorders. Molecular. http://molecularcasestudies.cshlp.org/content/5/3/a003913.short

Schapira, A. H. V., & Morris, H. R. (2020). Pathogenetic insights into young-onset Parkinson disease. Nature Reviews. Neurology, 16(5), 245–246.

Weil, R. S., & Morris, H. R. (2019). REM sleep behaviour disorder: an early window for prevention in neurodegeneration? Brain: A Journal of Neurology, 142(3), 498–501.