Professor Thomas Warner
Telephone:
Location:
- National Hospital for Neurology and Neurosurgery
GMC/GDC number:
3202403
Professional background
Professor Tom Warner graduated from the University of Oxford in 1984 with a BA in physiological sciences, and qualified as a medical practitioner in 1987 from the University of Oxford School of Medicine.
His higher neurological training was at the Royal Free Hospital, the National Hospital for Neurology and Neurosurgery, Queen Square, London and King’s College Hospital, London. He was appointed lecturer in neurogenetics at the Institute of Neurology and obtained his PhD at the University of London. In 2011 he was promoted to professor of clinical neurology at UCL Queen Square Institute of Neurology and the National Hospital for Neurology and Neurosurgery, London. Since 2012 he has been director of the Reta Lila Weston Institute at UCL Institute of Neurology and head of the Queen Square Brain Bank.
He specialises in disorders of movement and has particular expertise in Parkinson’s disease and allied conditions, dystonia, chorea, familial spasticity, Wilson’s disease and tremor.
Professor Warner is currently president elect of the Association of British Neurologists and will take up the role of President from 2021-2023.
His major research interests are in Parkinson’s disease and dystonia both with clinical studies and trials and investigating the cellular pathogenesis of these conditions.
Research interests
His major research interests are into the cellular pathogenesis of hereditary movement disorders including dystonia and parkinsonism as well as clinical studies in Huntington’s disease and experimental therapeutic trials in Parkinson’s disease and other movement disorders.
Publications
Selected Recent Publications
1. De Pablo-Fernandez E, Tur C, Revesz T, Lees AJ, Holton JL, Warner TT. Association of autonomic dysfunction with disease progression and survival in Parkinson disease. JAMA Neurol 2017;74:970-976
2. De Pablo-Fernández E, Warner T. Association between diabetes and subsequent Parkinson disease: A record-linkage cohort study. Neurology. 2019 May 7;92(19):925-926.
3. Barbosa PM, Djamshidian A, O'Sullivan SS, de Pablo-Fernandez E, Korlipara P,Morris HR, Bhatia KP, Limousin P, Foltynie T, Lees AJ, Warner TT. The long-term outcome of impulsive compulsive behaviours in Parkinson's disease. J Neurol Neurosurg Psychiatry. 2019 Nov;90(11):1288-1289
4. De Pablo-Fernández E, Lees AJ, Holton JL, Warner TT. Prognosis and Neuropathologic Correlation of Clinical Subtypes of Parkinson Disease. JAMA Neurol. 2019 Apr 1;76(4):470-479.
5. Shribman S, Reid E, Crosby AH, Houlden H, Warner TT. Hereditary spastic paraplegia: from diagnosis to emerging therapeutic approaches. Lancet Neurol. 2019 Jul 31. pii: S1474-4422(19)30235-2. doi: 10.1016/S1474-4422(19)30235-2
6. Barbosa P, Hapuarachchi B, Djamshidian A, Strand K, Lees AJ, de Silva R,Holton JL, Warner TT. Lower nucleus accumbens ?-synuclein load and D3 receptor levels in Parkinson's disease with impulsive compulsive behaviours. Brain. 2019 Nov 1;142(11):3580-3591.
7. Bettencourt C, Piras IS, Foti SC, Talboom J, Miki Y, Lashley T, Balazs R, ViréE, Warner TT, Huentelman MJ, Holton JL. Epigenomics and transcriptomics analyses of multiple system atrophy brain tissue supports a role for inflammatory processes in disease pathogenesis. Acta Neuropathol Commun. 2020 May 14;8(1):71.
8. Miki Y, Foti SC, Hansen D, Strand KM, Asi YT, Tsushima E, Jaunmuktane Z, LeesAJ, Warner TT, Quinn N, Ling H, Holton JL. Hippocampal ?-synuclein pathologycorrelates with memory impairment in multiple system atrophy. Brain. 2020 Jun1;143(6):1798-1810.
9. Hansen D, Ling H, Lashley T, Foley JA, Strand C, Eid TM, Holton JL, Warner TT. Novel clinicopathological characteristics differentiate dementia with Lewy bodies from Parkinson's disease dementia. Neuropathol Appl Neurobiol. 2020 Jul 27.
10. Shribman S, Heller C, Burrows M, Heslegrave A, Swift I, Foiani MS, Gillett GT, Tsochatzis EA, Rowe JB, Gerhard A, Butler CR, Masellis M, Bremner F, Martin A, Jung L, Cook P, Zetterberg H, Bandmann O, Rohrer JD, Warner TT. Plasma Neurofilament Light as a Biomarker of Neurological Involvement in Wilson's Disease. Mov Disord. 2020 Oct 20. doi: 10.1002/mds.28333.
11. Warner TT. Clinical and pathogenic themes in hereditary spastic paraplegia. Brain. 2020 Oct 1;143(10):2864-2866
12. de Pablo-Fernández E, González-Herrero B, Cerdán Santacruz D, Rossor MN, Schott JM, Lashley T, Holton JL, Fox NC, Revesz T, Warren JD, Jaunmuktane Z, Rohrer JD, Warner TT. A clinicopathological study of Movement Disorders in Frontotemporal Lobar Degeneration. Mov Disord Nov 2020